| P2093 | author name string | Kostas Pantopoulos | |
| | George Papanikolaou | |
| P2860 | cites work | Iron regulatory proteins control a mucosal block to intestinal iron absorption | Q42436152 |
| | Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis. | Q42913158 |
| | Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling | Q45234514 |
| | Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice | Q46475302 |
| | Hepcidin is decreased in TFR2 hemochromatosis | Q46624831 |
| | Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis | Q46902361 |
| | TfR2 links iron metabolism and erythropoiesis | Q48226439 |
| | Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis. | Q50530448 |
| | IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation. | Q50897468 |
| | Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. | Q52549517 |
| | STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo. | Q52576434 |
| | Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload. | Q52576436 |
| | Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin. | Q52613689 |
| | Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin. | Q52656784 |
| | Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia. | Q54091752 |
| | Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B. | Q54234772 |
| | Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. | Q54459192 |
| | High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin | Q56490134 |
| | Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2) | Q57397534 |
| | Hepcidin, a urinary antimicrobial peptide synthesized in the liver | Q24290609 |
| | Interleukin-6 induces hepcidin expression through STAT3 | Q24296906 |
| | HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression | Q24298843 |
| | STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation | Q24301291 |
| | Regulation of transferrin receptor 2 protein levels by transferrin | Q24301632 |
| | The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding | Q24309651 |
| | Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization | Q24310115 |
| | A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis | Q24310146 |
| | Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression | Q24316099 |
| | Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA) | Q24320295 |
| | Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis | Q24324055 |
| | Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor | Q24336313 |
| | Severe iron deficiency anemia in transgenic mice expressing liver hepcidin | Q24536163 |
| | Regulation of cellular iron metabolism | Q24610063 |
| | Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice | Q24617847 |
| | Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin | Q24632978 |
| | Pharmacological Targeting of the Hepcidin/Ferroportin Axis | Q26738350 |
| | Hepcidin in the diagnosis of iron disorders | Q26752500 |
| | Hepcidin: regulation of the master iron regulator | Q26800198 |
| | Primitive and definitive erythropoiesis in mammals | Q26851586 |
| | Regulation of Iron Metabolism by Hepcidin under Conditions of Inflammation | Q26852319 |
| | Mechanistic and regulatory aspects of intestinal iron absorption | Q26861531 |
| | Multi-copper oxidases and human iron metabolism | Q27002522 |
| | Iron homeostasis in host defence and inflammation | Q28083811 |
| | Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice | Q41028963 |
| | BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism | Q41871982 |
| | Regulation of hepcidin expression by inflammation-induced activin B. | Q41961541 |
| | Characterization of Putative Erythroid Regulators of Hepcidin in Mouse Models of Anemia. | Q41990428 |
| | HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. | Q42171228 |
| | The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin | Q28115763 |
| | Transferrin receptor is necessary for development of erythrocytes and the nervous system | Q28118509 |
| | A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload | Q28139987 |
| | Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis | Q28188379 |
| | Identification of erythroferrone as an erythroid regulator of iron metabolism | Q28240988 |
| | Regulation of iron transport and the role of transferrin | Q28253009 |
| | Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency | Q28297161 |
| | Lack of the bone morphogenetic protein BMP6 induces massive iron overload | Q28510138 |
| | Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype | Q28510894 |
| | Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis | Q28511505 |
| | Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein | Q28571434 |
| | Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice | Q28586797 |
| | Mitoferrin is essential for erythroid iron assimilation | Q28587125 |
| | Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2 | Q28587152 |
| | Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo | Q28591638 |
| | The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation | Q29620394 |
| | Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response | Q30418035 |
| | Iron control of erythroid development by a novel aconitase-associated regulatory pathway | Q30431455 |
| | Global transcriptome analyses of human and murine terminal erythroid differentiation | Q33697238 |
| | Regulation of ferritin genes and protein | Q34126332 |
| | Low hepcidin accounts for the proinflammatory status associated with iron deficiency. | Q34188665 |
| | Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I. | Q34197725 |
| | Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy | Q34267169 |
| | Systemic iron homeostasis | Q34378495 |
| | Anemia of chronic disease. | Q34401570 |
| | A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia. | Q34461765 |
| | Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia | Q34489655 |
| | Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution | Q34541622 |
| | Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression | Q34658174 |
| | Hfe acts in hepatocytes to prevent hemochromatosis. | Q34745897 |
| | Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice | Q34783878 |
| | In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact. | Q35025412 |
| | Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice | Q35027929 |
| | Regulation of TMPRSS6 by BMP6 and iron in human cells and mice | Q35125938 |
| | Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form. | Q35236046 |
| | The second transferrin receptor regulates red blood cell production in mice | Q35446281 |
| | Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload | Q35578602 |
| | SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis | Q35836771 |
| | Hepcidin in iron overload disorders | Q35847742 |
| | Suppression of hepcidin during anemia requires erythropoietic activity | Q35848905 |
| | Iron metabolism and toxicity | Q35998155 |
| | N- and C-terminal transactivation domains of GATA1 protein coordinate hematopoietic program | Q36033285 |
| | Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2. | Q36067487 |
| | Contributions of heme and nonheme iron to human nutrition | Q36089182 |
| | Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. | Q36119759 |
| | Isocitrate treatment of acute anemia of inflammation in a mouse model | Q36320635 |
| | The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression | Q36539421 |
| | Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. | Q36602744 |
| | Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice. | Q36625078 |
| | The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption | Q36728582 |
| | Erythropoietin and iron-restricted erythropoiesis | Q36767078 |
| | Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression | Q36843802 |
| | The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice. | Q36862425 |
| | Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice | Q36897141 |
| | Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency | Q37137793 |
| | Hepcidin regulation in the anemia of inflammation | Q37193954 |
| | Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes | Q37207754 |
| | Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells | Q37262477 |
| | Hypoxia-inducible factors link iron homeostasis and erythropoiesis | Q37620078 |
| | Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis | Q37624591 |
| | The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6. | Q37683823 |
| | Knockout mouse models of iron homeostasis | Q37872758 |
| | The IRP/IRE system in vivo: insights from mouse models | Q38239649 |
| | Beyond soluble transferrin receptor: old challenges and new horizons | Q38621816 |
| | NCOA4 Deficiency Impairs Systemic Iron Homeostasis | Q38802658 |
| | The mutual control of iron and erythropoiesis. | Q38830409 |
| | Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice | Q39173201 |
| | Diferric transferrin regulates transferrin receptor 2 protein stability | Q40524098 |
| | Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein | Q40979907 |
| P433 | issue | 6 | |
| P304 | page(s) | 399-413 | |
| P577 | publication date | 2017-04-06 | |
| P1433 | published in | IUBMB Life | Q15764029 |
| P1476 | title | Systemic iron homeostasis and erythropoiesis | |
| P478 | volume | 69 | |