Metabolic control of myofibers: promising therapeutic target for obesity and type 2 diabetes

scientific article published on 9 April 2017

Metabolic control of myofibers: promising therapeutic target for obesity and type 2 diabetes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/OBR.12530
P698PubMed publication ID28391659

P2093author name stringKang Yao
Yulong Yin
Bie Tan
Fengna Li
Yehui Duan
P2860cites workSignal-dependent nuclear export of a histone deacetylase regulates muscle differentiationQ24290523
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5Q24561772
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotypeQ24563940
Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6Q24607540
A Foxo/Notch pathway controls myogenic differentiation and fiber type specificationQ24678520
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosisQ24798075
Regulation of muscle fiber type and running endurance by PPARdeltaQ24799428
Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblastsQ27499254
Altered myogenesis in Six1-deficient miceQ28187781
The AMP-activated protein kinase cascade--a unifying system for energy controlQ28239257
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathwayQ28364039
Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signalingQ28475601
Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expressionQ28505164
Wnt/Lef1 signaling acts via Pitx2 to regulate somite myogenesisQ28506761
Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotypeQ28507339
Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotypeQ28539038
Myogenin induces a shift of enzyme activity from glycolytic to oxidative metabolism in muscles of transgenic miceQ28583773
Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotomeQ28585316
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndromeQ28592809
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibresQ29555845
Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activationQ30416660
Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin SensitivityQ30429437
Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivityQ33419373
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.Q33582672
MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance.Q33798765
Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathyQ33853875
Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exerciseQ33913651
The muscle fiber type-fiber size paradox: hypertrophy or oxidative metabolism?Q34213640
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagyQ34357433
MyoD protein is differentially accumulated in fast and slow skeletal muscle fibres and required for normal fibre type balance in rodentsQ34419971
Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shiftQ34629944
Thyroid hormone regulates muscle fiber type conversion via miR-133a1Q34759387
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscleQ35163135
Excitation‐transcription coupling in skeletal muscle: the molecular pathways of exerciseQ35207442
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber typeQ35207780
Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistanceQ35574642
Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.Q36002900
Activity-dependent and -independent nuclear fluxes of HDAC4 mediated by different kinases in adult skeletal muscleQ36321466
Signaling pathways in skeletal muscle remodelingQ36498310
Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performanceQ36711254
Myostatin knockout drives browning of white adipose tissue through activating the AMPK‐PGC1α‐Fndc5 pathway in muscleQ36788726
Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activationQ36930240
Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistanceQ37163525
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.Q37232094
The effects of a soluble activin type IIB receptor on obesity and insulin sensitivityQ37440507
Chapter 2. Calcineurin signaling and the slow oxidative skeletal muscle fiber typeQ37600448
Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism.Q37625590
A second look into fibre typing--relation to meat qualityQ37726492
Fiber types in mammalian skeletal musclesQ37947567
Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.Q38321731
Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryoQ39045174
Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese miceQ39280475
Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblastsQ39926265
The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscleQ40190344
Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells.Q40328341
The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryoQ40424101
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathwayQ40446884
Exercise, Glucose Transport, and Insulin SensitivityQ41724116
Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for beta-cateninQ41769558
Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafishQ42156236
Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia.Q42657469
Sox6 is required for normal fiber type differentiation of fetal skeletal muscle in miceQ43767931
Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle cultureQ44239011
Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathwaysQ44564216
Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscleQ44756162
Retinoic acid activates myogenesis in vivo through Fgf8 signallingQ46826756
Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish.Q47073749
Pbx homeodomain proteins direct Myod activity to promote fast-muscle differentiationQ47074013
Six1a is required for the onset of fast muscle differentiation in zebrafishQ47074076
Muscle fiber type is associated with obesity and weight lossQ47186050
Regulation of the nuclear export of the transcription factor NFATc1 by protein kinases after slow fibre type electrical stimulation of adult mouse skeletal muscle fibres.Q50703706
Ras is involved in nerve-activity-dependent regulation of muscle genes.Q51413336
Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo.Q51791503
Specification of vertebrate slow-twitch muscle fiber fate by the transcriptional regulator Blimp1.Q51947553
MusTRD can regulate postnatal fiber-specific expressionQ52025298
Low muscle mass is associated with metabolic syndrome in Korean adolescents: the Korea National Health and Nutrition Examination Survey 2009-2011.Q53130780
Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in miceQ54034693
PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetesQ57848914
P433issue6
P921main subjecttype 2 diabetesQ3025883
P304page(s)647-659
P577publication date2017-04-09
P1433published inObesity ReviewsQ15716706
P1476titleMetabolic control of myofibers: promising therapeutic target for obesity and type 2 diabetes
P478volume18

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cites work (P2860)
Q47123305Alteration of muscle fiber characteristics and the AMPK-SIRT1-PGC-1α axis in skeletal muscle of growing pigs fed low-protein diets with varying branched-chain amino acid ratios.
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Q92967182ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity
Q57091823High-Intensity Interval Training Is Equivalent to Moderate-Intensity Continuous Training for Short- and Medium-Term Outcomes of Glucose Control, Cardiometabolic Risk, and Microvascular Complication Markers in Men With Type 2 Diabetes
Q38650511Interleukin-15 in obesity and metabolic dysfunction: current understanding and future perspectives.
Q47755607Key factors involved in obesity development
Q91787138Relationship between diet/exercise and pharmacotherapy to enhance the GLP-1 levels in type 2 diabetes

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