| scholarly article | Q13442814 |
| P2093 | author name string | Jean-Baptiste Guy | |
| Nicolas Magné | |||
| Chloé Rancoule | |||
| Alexis Vallard | |||
| Sophie Espenel | |||
| Jane-Chloé Trone | |||
| Julien Langrand-Escure | |||
| Amel Rehailia-Blanchard | |||
| Anis El Meddeb Hamrouni | |||
| Majed Ben-Mrad | |||
| Yaxiong Xia | |||
| P2860 | cites work | Blockade of lysophosphatidic acid receptors LPAR1/3 ameliorates lung fibrosis induced by irradiation | Q84044652 |
| Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells | Q44493287 | ||
| Lysophosphatidic acid interacts with transforming growth factor-beta signaling to mediate keratinocyte growth arrest and chemotaxis | Q45105317 | ||
| Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells. | Q45947801 | ||
| ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy | Q46843010 | ||
| The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak | Q46861210 | ||
| LPA1 receptor activation promotes renal interstitial fibrosis | Q46899860 | ||
| Cancer stem cells, cornerstone of radioresistance and perspectives for radiosensitization: glioblastoma as an example | Q53130086 | ||
| Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence. | Q54769190 | ||
| Radial Scars in Benign Breast-Biopsy Specimens and the Risk of Breast Cancer | Q57751053 | ||
| Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion | Q58665639 | ||
| Hypoxia Enhances Lysophosphatidic Acid Responsiveness in Ovarian Cancer Cells and Lysophosphatidic Acid Induces Ovarian Tumor MetastasisIn vivo | Q59210399 | ||
| Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis | Q59304976 | ||
| Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C | Q59939737 | ||
| Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity | Q59939744 | ||
| HMG-CoA Reductase Inhibitors Decrease Angiotensin II–Induced Vascular Fibrosis | Q61854913 | ||
| How does the extracellular matrix direct gene expression? | Q71846181 | ||
| Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells | Q73253526 | ||
| Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency | Q73430532 | ||
| [Reversibility of radiation-induced fibroatrophy] | Q77721569 | ||
| Dose response and latency for radiation-induced fibrosis, edema, and neuropathy in breast cancer patients | Q77947503 | ||
| Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal | Q80605710 | ||
| Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conserving surgery enhances late toxicities: long-term results of the ARCOSEIN multicenter randomized study | Q82856155 | ||
| Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds | Q21146433 | ||
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Mechanisms in the Pathogenesis of Asbestosis and Silicosis | Q22299314 | ||
| Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis | Q24297546 | ||
| Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo | Q26741062 | ||
| Wnt Signaling in Cancer Stem Cell Biology | Q26746101 | ||
| Radiation-induced neuropathy in cancer survivors | Q26822955 | ||
| Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy | Q27015257 | ||
| Lysophospholipid receptors in drug discovery | Q27692680 | ||
| Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy | Q28140319 | ||
| The emerging role of lysophosphatidic acid in cancer | Q28191543 | ||
| Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes | Q28237640 | ||
| Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate | Q28239967 | ||
| Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate | Q28260852 | ||
| LPA receptors: subtypes and biological actions | Q28269613 | ||
| Transforming growth factor-beta regulation of immune responses | Q28303115 | ||
| A molecular signature of metastasis in primary solid tumors | Q29614442 | ||
| Basement membranes: structure, assembly and role in tumour angiogenesis | Q29622882 | ||
| Molecular characterization of the tumor microenvironment in breast cancer | Q31095898 | ||
| Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood. | Q43945285 | ||
| Platelet-derived growth factor-BB and lysophosphatidic acid distinctly regulate hepatic myofibroblast migration through focal adhesion kinase | Q44222273 | ||
| Gene expression signatures of morphologically normal breast tissue identify basal-like tumors | Q33261032 | ||
| Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer | Q33326112 | ||
| Functional Wnt signaling is increased in idiopathic pulmonary fibrosis | Q33334369 | ||
| Gene expression profiling of the tumor microenvironment during breast cancer progression | Q33404889 | ||
| Autotaxin--an LPA producing enzyme with diverse functions | Q33584900 | ||
| Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma. | Q33842405 | ||
| Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature | Q33974891 | ||
| A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model | Q34116805 | ||
| Sphingosine 1-phosphate and cancer | Q34121255 | ||
| Lysophosphatidic acid is a bioactive mediator in ovarian cancer | Q34133820 | ||
| Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases | Q34148745 | ||
| Bioactive lipids, LPC and LPA, are novel prometastatic factors and their tissue levels increase in response to radio/chemotherapy | Q34518525 | ||
| Radiation and ceramide-induced apoptosis | Q35208833 | ||
| Effects of radiation on normal tissue: consequences and mechanisms. | Q35215796 | ||
| Apoptosis, Chemoresistance, and Breast Cancer: Insights From the MCF-7 Cell Model System | Q35552651 | ||
| Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid | Q35597324 | ||
| Regulation of PDGF and its receptors in fibrotic diseases | Q35811100 | ||
| Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity | Q35828524 | ||
| Cell surface receptors in lysophospholipid signaling | Q35844009 | ||
| Biology of LPA in health and disease | Q35844022 | ||
| Insights into the pharmacological relevance of lysophospholipid receptors | Q35853199 | ||
| The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair | Q35888752 | ||
| The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. | Q35948246 | ||
| Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis | Q36016449 | ||
| Radiation-induced fibrosis: mechanisms and implications for therapy | Q36070558 | ||
| The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury | Q36246898 | ||
| Mitigation of radiation injury by selective stimulation of the LPA2 receptor | Q36377955 | ||
| Influence of connective tissue diseases on the expression of radiation side effects: a systematic review | Q36381603 | ||
| The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival | Q36395318 | ||
| Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research | Q36663274 | ||
| Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis | Q36664243 | ||
| Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways | Q36682162 | ||
| The role of PDGF in radiation oncology | Q36705396 | ||
| Current management for late normal tissue injury: radiation-induced fibrosis and necrosis | Q36774557 | ||
| Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis | Q37012626 | ||
| Tumor stroma and regulation of cancer development | Q37014752 | ||
| Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis | Q37014825 | ||
| Role of transforming growth factor-beta superfamily signaling pathways in human disease | Q37099520 | ||
| Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines | Q37177631 | ||
| Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect | Q37194251 | ||
| Lysophosphatidic acid (LPA) and its receptors | Q37361117 | ||
| PDGF-D signaling: a novel target in cancer therapy | Q37370274 | ||
| Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. | Q37391105 | ||
| Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus | Q37437259 | ||
| Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression | Q37486804 | ||
| Hallmarks of cancer: interactions with the tumor stroma. | Q37704659 | ||
| Treatment for radiation-induced pulmonary late effects: spoiled for choice or looking in the wrong direction? | Q37768188 | ||
| Lysophosphatidic acid-1-receptor targeting agents for fibrosis. | Q37857284 | ||
| Radiation Fibrosis — Current Clinical and Therapeutic Perspectives | Q38011370 | ||
| New insights into the mechanism of notch signalling in fibrosis. | Q38026842 | ||
| Lysoglycerophospholipids in chronic inflammatory disorders: the PLA(2)/LPC and ATX/LPA axes | Q38032353 | ||
| Strategies for anti-fibrotic therapies | Q38069742 | ||
| Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer | Q38163204 | ||
| Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer | Q38212057 | ||
| Lysophosphatidic acid as a lipid mediator with multiple biological actions | Q38286968 | ||
| Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer | Q38364011 | ||
| Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-β pathways | Q38769001 | ||
| Towards a unified approach in the modeling of fibrosis: A review with research perspectives. | Q38808519 | ||
| Lysophosphatidic acid receptor‐3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells | Q39429482 | ||
| Pharmacokinetic and Pharmacodynamic Characterization of an Oral Lysophosphatidic Acid Type 1 Receptor-Selective Antagonist | Q39619856 | ||
| Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis. | Q39905542 | ||
| Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1alpha and the PI3K pathway | Q39938130 | ||
| Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression | Q40291669 | ||
| Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells | Q40608265 | ||
| LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway | Q40657618 | ||
| Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis | Q40720006 | ||
| Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells | Q40806084 | ||
| Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity | Q41272671 | ||
| Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts | Q41479857 | ||
| Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development | Q41490870 | ||
| Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis | Q41763814 | ||
| Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. | Q42555356 | ||
| Effects of lysophosphatidic acid and its receptors LPA⅓ on radiation pneumonitis | Q42839221 | ||
| ATX expression and LPA signalling are vital for the development of the nervous system. | Q43192412 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 26 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | dysplasia | Q1128996 |
| lipid | Q11367 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 43543-43554 | |
| P577 | publication date | 2017-03-29 | |
| 2017-06-27 | |||
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Oncotarget | Q1573155 |
| P1476 | title | Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index | |
| P478 | volume | 8 |
| Q52689639 | Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation |
| Q50094814 | Lysophosphatidate Signaling: The Tumor Microenvironment's New Nemesis |
| Q91565659 | Targeting Tumor Microenvironment by Small-Molecule Inhibitors |
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