Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors

scientific article published on January 1, 2013

Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/1440-1681.12026
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2F1440-1681.12026
https://onlinelibrary.wiley.com/doi/pdf/10.1111/1440-1681.12026
P698PubMed publication ID23110505

P2093author name stringYan Zou
Tao Jiang
Wen-Jing Xing
Huan Ren
Xiao-Hong Lv
Qing-Lian Han
Yu-Cui Dong
Zhen-Ling Deng
P2860cites workDisruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cellsQ24550891
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Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapyQ30437740
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Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and RadioresistanceQ34105339
mTor is required for hypertrophy of Pten-deficient neuronal soma in vivoQ34542438
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A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant gliomaQ37003323
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Long-term exposure to imatinib reduced cancer stem cell ability through induction of cell differentiation via activation of MAPK signaling in glioblastoma cellsQ39308739
The functional expression of calcium-sensing receptors in BRL cells and related signal transduction pathway responsible for intracellular calcium elevationQ39701651
Suppression of invasive properties of colorectal carcinoma SW480 cells by 15-hydroxyprostaglandin dehydrogenase geneQ39912197
Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cellsQ40243368
Effects of cotransfection of antisense-EGFR and wild-type PTEN cDNA on human glioblastoma cellsQ40268565
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinibQ43742602
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.Q46410598
Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosisQ46448054
Erlotinib in gliomas: should selection be based on EGFR and Akt analyses?Q46547355
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.Q48445523
Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomasQ48475005
Amplification and overexpression of epidermal growth factor receptor gene in glioblastomas of Chinese patients correlates with patient's age but not with tumor's clinicopathological pathwayQ48776725
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.Q55474170
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectglioblastomaQ282142
P304page(s)13-21
P577publication date2013-01-01
P1433published inClinical and Experimental Pharmacology and PhysiologyQ5133807
P1476titleEffects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors
P478volume40

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cites work (P2860)
Q35804765Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells
Q37362563Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes.
Q55456636Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.
Q33746514Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science
Q39136061Is Mda‐7/IL‐24 a Potential Target and Biomarker for Enhancing Drug Sensitivity in Human Glioma U87 Cell Line?
Q34062038JAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma
Q38102636Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding
Q38987085mTOR inhibition and levels of the DNA repair protein MGMT in T98G glioblastoma cells

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