Mutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle of phytochromes

scientific article

Mutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle of phytochromes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M709355200
P932PMC publication ID2431007
P698PubMed publication ID18192276

P50authorDavid von StettenQ47087372
Daniel H. MurgidaQ51273556
Katrina T. ForestQ89722501
Peter HildebrandtQ28735523
Maria Andrea MroginskiQ41660496
P2093author name stringRichard D Vierstra
Joseph M Walker
Junrui Zhang
Jeremiah R Wagner
Mina Günther
P2860cites workResonance raman analysis of chromophore structure in the lumi-R photoproduct of phytochromeQ46204706
Light-induced proton release of phytochrome is coupled to the transient deprotonation of the tetrapyrrole chromophoreQ46630021
A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochromeQ46808052
Assembly of synthetic locked chromophores with agrobacterium phytochromes Agp1 and Agp2.Q50730327
The chromophore structural changes during the photocycle of phytochrome: a combined resonance Raman and quantum chemical approach.Q51923431
Highly conserved residues Asp-197 and His-250 in Agp1 phytochrome control the proton affinity of the chromophore and Pfr formation.Q53511141
Resonance Raman spectroscopic study of the tryptic 39-kDa fragment of phytochromeQ57654221
Protonation State and Structural Changes of the Tetrapyrrole Chromophore during the Pr→ PfrPhototransformation of Phytochrome: A Resonance Raman Spectroscopic Study†Q57654232
Serine-to-alanine substitutions at the amino-terminal region of phytochrome A result in an increase in biological activityQ67599799
Resonance Raman spectra of the intermediates in phototransformation of large phytochrome: deprotonation of the chromophore in the bleached intermediateQ72719842
Bacteriophytochromes: phytochrome-like photoreceptors from nonphotosynthetic eubacteriaQ73316575
FTIR studies of phytochrome photoreactions reveal the C=O bands of the chromophore: consequences for its protonation states, conformation, and protein interactionQ77320727
High resolution structure of Deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolutionQ27643899
Crystal structure of the chromophore binding domain of an unusual bacteriophytochrome, RpBphP3, reveals residues that modulate photoconversionQ27646817
The biliverdin chromophore binds covalently to a conserved cysteine residue in the N-terminus of Agrobacterium phytochrome Agp1Q28492368
Phytochrome structure and signaling mechanisms.Q30486809
Probing protein-chromophore interactions in Cph1 phytochrome by mutagenesisQ30814602
First steps in the phytochrome phototransformation: a comparative femtosecond study on the forward (Pr --> Pfr) and back reaction (Pfr --> Pr).Q30977761
Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassaQ34232866
Multiple roles of a conserved GAF domain tyrosine residue in cyanobacterial and plant phytochromesQ34293819
Phytochrome photosensory signalling networksQ34522847
In vitro assembly of phytochrome B apoprotein with synthetic analogs of the phytochrome chromophoreQ34757212
C-type cytochrome formation: chemical and biological enigmasQ35989345
Eukaryotic phytochromes: light-regulated serine/threonine protein kinases with histidine kinase ancestryQ36817238
Chromophore structure of the physiologically active form (P(fr)) of phytochromeQ37617714
Harnessing phytochrome's glowing potentialQ37713921
Carboxy-terminal deletion analysis of oat phytochrome A reveals the presence of separate domains required for structure and biological activityQ38319463
Phylogenetic analysis of the phytochrome superfamily reveals distinct microbial subfamilies of photoreceptorsQ40726493
Probing the photoreaction mechanism of phytochrome through analysis of resonance Raman vibrational spectra of recombinant analogues.Q41723225
Phytochrome Cph1 from the cyanobacterium Synechocystis PCC6803. Purification, assembly, and quaternary structure.Q43725640
Bacteriophytochromes are photochromic histidine kinases using a biliverdin chromophoreQ43822034
Mechanism of Cph1 phytochrome assembly from stopped-flow kinetics and circular dichroismQ44657969
Photochromic biliproteins from the cyanobacterium Anabaena sp. PCC 7120: lyase activities, chromophore exchange, and photochromism in phytochrome AphA.Q45045788
Determination of the chromophore structures in the photoinduced reaction cycle of phytochromeQ45196758
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectDeinococcus radioduransQ386827
mutational analysisQ1955810
P1104number of pages15
P304page(s)12212-12226
P577publication date2008-01-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleMutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle of phytochromes
P478volume283

Reverse relations

cites work (P2860)
Q35031793"Turn-on" protein fluorescence: in situ formation of cyanine dyes
Q33891776A brief history of phytochromes
Q30360192A knot in the protein structure - probing the near-infrared fluorescent protein iRFP designed from a bacterial phytochrome.
Q42577982A polarity probe for monitoring light-induced structural changes at the entrance of the chromophore pocket in a bacterial phytochrome
Q30484273A second conserved GAF domain cysteine is required for the blue/green photoreversibility of cyanobacteriochrome Tlr0924 from Thermosynechococcus elongatus.
Q36423363Allosteric effects of chromophore interaction with dimeric near-infrared fluorescent proteins engineered from bacterial phytochromes.
Q27683806An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging
Q37495177Apo-bacteriophytochromes modulate bacterial photosynthesis in response to low light
Q55241763Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor.
Q35433889Atomic force microscopy of red-light photoreceptors using peakforce quantitative nanomechanical property mapping
Q41573558Bacterial Phytochromes, Cyanobacteriochromes and Allophycocyanins as a Source of Near-Infrared Fluorescent Probes.
Q37830693Bacterial phytochromes: more than meets the light
Q92412925Bacteriophytochromes - from informative model systems of phytochrome function to powerful tools in cell biology
Q34078020Biliverdin amides reveal roles for propionate side chains in bilin reductase recognition and in holophytochrome assembly and photoconversion.
Q24621011Bright and stable near-infrared fluorescent protein for in vivo imaging
Q37191930Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
Q35674544Characterization of two thermostable cyanobacterial phytochromes reveals global movements in the chromophore-binding domain during photoconversion
Q33446909Chromophore structure of cyanobacterial phytochrome Cph1 in the Pr state: reconciling structural and spectroscopic data by QM/MM calculations
Q27657253Conformational differences between the Pfr and Pr states in Pseudomonas aeruginosa bacteriophytochrome
Q27652212Crystal structure of Pseudomonas aeruginosa bacteriophytochrome: Photoconversion and signal transduction
Q27684509Crystal structure of the photosensing module from a red/far-red light-absorbing plant phytochrome
Q27684618Crystallographic and Electron Microscopic Analyses of a Bacterial Phytochrome Reveal Local and Global Rearrangements during Photoconversion
Q37447795Cyanochromes are blue/green light photoreversible photoreceptors defined by a stable double cysteine linkage to a phycoviolobilin-type chromophore
Q41528084Designing brighter near-infrared fluorescent proteins: insights from structural and biochemical studies.
Q91697197Distinct chromophore-protein environments enable asymmetric activation of a bacteriophytochrome-activated diguanylate cyclase
Q30487057Distinct classes of red/far-red photochemistry within the phytochrome superfamily
Q30356820Dynamic structural changes underpin photoconversion of a blue/green cyanobacteriochrome between its dark and photoactivated states.
Q33789962Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase.
Q36745290Engineering of bacterial phytochromes for near-infrared imaging, sensing, and light-control in mammals
Q37640884Eukaryotic algal phytochromes span the visible spectrum
Q48050519FRET in a Synthetic Flavin- and Bilin-binding Protein
Q34020471FTIR Spectroscopy Revealing Light-Dependent Refolding of the Conserved Tongue Region of Bacteriophytochrome
Q37111895Far-red light photoactivatable near-infrared fluorescent proteins engineered from a bacterial phytochrome
Q35896719Fast Photochemistry of Prototypical Phytochromes-A Species vs. Subunit Specific Comparison
Q42571161Fluorescence of phytochrome adducts with synthetic locked chromophores
Q45914123Fluorescence quantum yield and photochemistry of bacteriophytochrome constructs.
Q30383936From photon to signal in phytochromes: similarities and differences between prokaryotic and plant phytochromes.
Q90494776Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
Q90321229High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures
Q38700642How to Increase Brightness of Near-Infrared Fluorescent Proteins in Mammalian Cells
Q64278423Influence of the N-terminal segment and the PHY-tongue element on light-regulation in bacteriophytochromes
Q41835899Interaction of Biliverdin Chromophore with Near-Infrared Fluorescent Protein BphP1-FP Engineered from Bacterial Phytochrome.
Q40942309Light-induced Changes in the Dimerization Interface of Bacteriophytochromes
Q43120266Light-induced activation of bacterial phytochrome Agp1 monitored by static and time-resolved FTIR spectroscopy
Q37725820Light-induced conformational changes of the chromophore and the protein in phytochromes: bacterial phytochromes as model systems.
Q24652377Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome
Q40199517Minimal domain of bacterial phytochrome required for chromophore binding and fluorescence.
Q46268214Modeling of phytochrome absorption spectra.
Q36341915Molecular Basis of Spectral Diversity in Near-Infrared Phytochrome-Based Fluorescent Proteins
Q30378057NMR chemical shift pattern changed by ammonium sulfate precipitation in cyanobacterial phytochrome Cph1.
Q52904756NMR spectroscopic investigation of mobility and hydrogen bonding of the chromophore in the binding pocket of phytochrome proteins.
Q54385554Near infrared fluorescent biliproteins generated from bacteriophytochrome AphB of Nostoc sp. PCC 7120.
Q91761084Near-Infrared Markers based on Bacterial Phytochromes with Phycocyanobilin as a Chromophore
Q59133449Near-infrared STED nanoscopy with an engineered bacterial phytochrome
Q36005927Near-infrared fluorescent proteins engineered from bacterial phytochromes
Q30368081NpR3784 is the prototype for a distinctive group of red/green cyanobacteriochromes using alternative Phe residues for photoproduct tuning.
Q57092273On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome
Q41469400On the origin of fluorescence in bacteriophytochrome infrared fluorescent proteins
Q34509776Origins of fluorescence in evolved bacteriophytochromes
Q42652544Photosensing and Thermosensing by Phytochrome B Require Both Proximal and Distal Allosteric Features within the Dimeric Photoreceptor
Q90601342Phytochrome evolution in 3D: deletion, duplication, and diversification
Q26996777Phytochromes: an atomic perspective on photoactivation and signaling
Q33927108Proton-transfer and hydrogen-bond interactions determine fluorescence quantum yield and photochemical efficiency of bacteriophytochrome
Q63610134Protonation of the Biliverdin IXα Chromophore in the Red and Far-Red Photoactive States of a Bacteriophytochrome
Q33934646Quaternary organization of a phytochrome dimer as revealed by cryoelectron microscopy
Q36316730Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor
Q33402467Residues clustered in the light-sensing knot of phytochrome B are necessary for conformer-specific binding to signaling partner PIF3.
Q27683575Signal amplification and transduction in phytochrome photosensors
Q55714906Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo.
Q38065250Solid-state NMR spectroscopy to probe photoactivation in canonical phytochromes.
Q27651908Solution Structure of a Cyanobacterial Phytochrome GAF Domain in the Red-Light-Absorbing Ground State
Q48043325Spectroscopic Investigation on the Primary Photoreaction of Bathy Phytochrome Agp2-Pr of Agrobacterium fabrum: Isomerization in a pH-dependent H-bond Network
Q38788321Structural and Vibrational Characterization of the Chromophore Binding Site of Bacterial Phytochrome Agp1.
Q58693723Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome
Q27658962Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Q30313163Structural heterogeneity in a parent ground-state structure of AnPixJg2 revealed by theory and spectroscopy
Q42144097Structure of the biliverdin cofactor in the Pfr state of bathy and prototypical phytochromes
Q27676501Structure-guided Engineering Enhances a Phytochrome-based Infrared Fluorescent Protein
Q44107439Structure-guided engineering of plant phytochrome B with altered photochemistry and light signaling.
Q40456276The fungal phytochrome FphA from Aspergillus nidulans.
Q36955002The phytochrome red/far-red photoreceptor superfamily
Q38850025The role of local and remote amino acid substitutions for optimizing fluorescence in bacteriophytochromes: A case study on iRFP
Q64067978The unfolding of iRFP713 in a crowded milieu
Q64070955Time-Resolved Macromolecular Crystallography at Pulsed X-ray Sources
Q34652820Two ground state isoforms and a chromophore D-ring photoflip triggering extensive intramolecular changes in a canonical phytochrome
Q54374841Tyrosine 263 in cyanobacterial phytochrome Cph1 optimizes photochemistry at the prelumi-R→lumi-R step.
Q35922394Ultrafast excited-state dynamics and fluorescence deactivation of near-infrared fluorescent proteins engineered from bacteriophytochromes.

Search more.