Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem

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Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem is …
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scholarly articleQ13442814

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P356DOI10.1177/0269881113515065
P8608Fatcat IDrelease_x4ff4nngqbdxzon2vgh3jowcpq
P698PubMed publication ID24429224
P5875ResearchGate publication ID259765849

P50authorDonatella MarazzitiQ27149392
Liliana Dell'OssoQ72932960
Lionella PalegoQ90229020
Mario Catena-Dell''OssoQ117231910
Gino GiannacciniQ46649946
Stefano BaroniQ57033213
Laura BettiQ57327715
P2093author name stringMaura Castagna
Antonio G Naccarato
Antonio Luccachini
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Differential profile of typical, atypical and third generation antipsychotics at human 5-HT7a receptors coupled to adenylyl cyclase: detection of agonist and inverse agonist properties.Q34677182
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Reduced basal and stimulated (isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimer's disease correlated with histopathological changesQ42476813
Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victimsQ42499061
Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptorQ43177165
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Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635.Q44014139
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonismQ44225342
Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET studyQ44317508
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Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonismQ45056326
Cloned human 5-HT1A receptor pharmacology determined using agonist binding and measurement of cAMP accumulationQ45105452
(R)-8-OH-DPAT preferentially increases dopamine release in rat medial prefrontal cortexQ48243441
Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactionsQ48309573
Effects of postmortem delay on serotonin and (+)8-OH-DPAT-mediated inhibition of adenylyl cyclase activity in rat and human brain tissues.Q48313093
Pharmacological characterization of the 5-hydroxytryptamine receptor coupled to adenylyl cyclase stimulation in human brainQ48359039
Clozapine has sub-micromolar affinity for 5-HT1A receptors in human brain tissueQ48419142
Olanzapine increases in vivo dopamine and norepinephrine release in rat prefrontal cortex, nucleus accumbens and striatumQ48486128
5-HT1A receptor agonist properties of the antipsychotic, nemonapride: comparison with bromerguride and clozapineQ48594004
Serotonin1A receptors are increased in postmortem prefrontal cortex in schizophreniaQ49119845
Behavioral effects of flibanserin (BIMT 17).Q51087336
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)320-328
P577publication date2014-01-15
P1433published inJournal of PsychopharmacologyQ6295819
P1476titleClozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem
P478volume28

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cites work (P2860)
Q38700728CYP2C19*17 protects against metabolic complications of clozapine treatment
Q36206591Clozapine modifies the differentiation program of human adipocytes inducing browning
Q47280410Clozapine-induced dysphagia with secondary substantial weight loss

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