CD24 activates the NLRP3 inflammasome through c-Src kinase activity in a model of the lining epithelium of inflamed periodontal tissues

scientific article published on 9 December 2014

CD24 activates the NLRP3 inflammasome through c-Src kinase activity in a model of the lining epithelium of inflamed periodontal tissues is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IID3.40
P932PMC publication ID4386918
P698PubMed publication ID25866631
P5875ResearchGate publication ID269419732

P2093author name stringHong Yu
Wei Guo
Neil Hunter
Zhonghao Liu
Pishan Yang
Ping Ye
P2860cites workThe inflammasomeQ24276127
Regulation of E-cadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cellsQ24300610
The inflammasomesQ24304087
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-betaQ24305136
Role of the inflammasome, IL-1β, and IL-18 in bacterial infectionsQ24627445
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1Q29614473
Dynamic migration of γδ intraepithelial lymphocytes requires occludinQ30513960
Identification of epithelial auto-antigens associated with periodontal diseaseQ31141922
CD24 regulated gene expression and distribution of tight junction proteins is associated with altered barrier function in oral epithelial monolayersQ33399296
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction.Q33874812
Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalisQ34010067
Molecular and cell biology of the gingivaQ34200815
The Nlrp3 inflammasome: contributions to intestinal homeostasisQ34762033
Sialidase and sialoglycoproteases can modulate virulence in Porphyromonas gingivalisQ35328858
Porphyromonas gingivalis invasion of gingival epithelial cellsQ35442373
Occludin is required for apoptosis when claudin-claudin interactions are disruptedQ35783599
The junctional epithelium: from health to diseaseQ35992204
The bacterial etiology of destructive periodontal disease: current conceptsQ36056602
The role of Src kinase in macrophage-mediated inflammatory responsesQ36418104
Porphyromonas gingivalis-epithelial cell interactions in periodontitisQ36457270
Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine productionQ36710720
Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cellsQ37179132
Interleukin-18 and IL-18 binding proteinQ37220336
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.Q37396101
Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infectionQ37548150
Molecular mechanisms involved in inflammasome activationQ37588947
Cell death and infection: a double-edged sword for host and pathogen survival.Q37962256
Signaling in innate immunity and inflammationQ37980557
Tight junction-related human diseasesQ38077200
Binding of Streptococcus gordonii to oral epithelial monolayers increases paracellular barrier functionQ39240597
A peptidomimetic tight junction modulator to improve regional analgesiaQ39360747
Modulation of epithelial tight junctions by TGF-beta 3 in cultured oral epithelial cellsQ39389578
Ligation of CD24 expressed by oral epithelial cells induces kinase dependent decrease in paracellular permeability mediated by tight junction proteinsQ39497043
Regulation of NLRP3 and AIM2 inflammasome gene expression levels in gingival fibroblasts by oral biofilmsQ39546624
Effects of Porphyromonas gingivalis infection on human gingival epithelial barrier function in vitro.Q39630745
Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2.Q40565984
Streptococci and Actinomyces induce antibodies which cross react with epithelial antigens in periodontitisQ40668218
Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530Q41130127
Chronic adult periodontitis and burst progression may reflect local neutrophil defects due to perivascular hyaline depositsQ41141165
The behaviour of human oral squamous cell carcinoma in cell cultureQ41743200
ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalisQ41818799
ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis.Q43185488
Interleukin-18 facilitates neutrophil transmigration via myosin light chain kinase-dependent disruption of occludin, without altering epithelial permeability.Q46037099
Mechanical damage to Escherichia coli cells in a model of amino-acid crystal fermentation.Q54346654
Expression pattern of adhesion molecules in junctional epithelium differs from that in other gingival epithelia.Q54466200
Some microbiological, histopathological and immunohistochemical characteristics of progressive periodontal diseaseQ72536835
Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's diseaseQ73288644
Decoding cell death signals in inflammation and immunityQ83372831
Down-regulation of NLRP3 inflammasome in gingival fibroblasts by subgingival biofilms: involvement of Porphyromonas gingivalisQ83951006
Effectiveness of non-surgical treatment to reduce il-18 levels in the gingival crevicular fluid of patients with periodontal diseaseQ85601474
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectinflammasome complexQ412405
P304page(s)239-253
P577publication date2014-12-09
P1433published inImmunity, Inflammation and DiseaseQ27725961
P1476titleCD24 activates the NLRP3 inflammasome through c-Src kinase activity in a model of the lining epithelium of inflamed periodontal tissues
P478volume2

Reverse relations

cites work (P2860)
Q47214655Analysis of differential expression of tight junction proteins in cultured oral epithelial cells altered by Porphyromonas gingivalis, Porphyromonas gingivalis lipopolysaccharide, and extracellular adenosine triphosphate
Q91723199Cell culture models of oral mucosal barriers: A review with a focus on applications, culture conditions and barrier properties
Q52682338Free Total Rhubarb Anthraquinones Protect Intestinal Injury via Regulation of the Intestinal Immune Response in a Rat Model of Severe Acute Pancreatitis.
Q54123515Impaired Na+-K+-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.
Q48123419Impaired bone healing at tooth extraction sites in CD24-deficient mice: A pilot study
Q40111437Necroptosis in the periodontal homeostasis: Signals emanating from dying cells.
Q50900027Salivary Levels of NLRP3 Inflammasome-Related Proteins as Potential Biomarkers of Periodontal Clinical Status.
Q35825064The activation of pyrin domain-containing-3 inflammasome depends on lipopolysaccharide from Porphyromonas gingivalis and extracellular adenosine triphosphate in cultured oral epithelial cells
Q27309045Three/four-dimensional (3D/4D) microscopic imaging and processing in clinical dental research

Search more.