TTP as a surrogate endpoint in advanced hepatocellular carcinoma treated with molecular targeted therapy: meta-analysis of randomised controlled trials

scientific article published on 13 October 2016

TTP as a surrogate endpoint in advanced hepatocellular carcinoma treated with molecular targeted therapy: meta-analysis of randomised controlled trials is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.2016.322
P932PMC publication ID5104893
P698PubMed publication ID27736843

P50authorSeock-Ah ImQ58821370
Do-Youn OhQ87569618
Tae-You KimQ87569625
Sae-Won HanQ91404079
Jung-Hwan YoonQ39903625
P2093author name stringYoon Jun Kim
Kyung-Hun Lee
Tae-Yong Kim
Jeong-Hoon Lee
Su Jong Yu
Eun Ju Cho
Myoung-Jin Jang
Dae-Won Lee
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Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trialsQ31014850
Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trialQ33410643
Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trialQ33423800
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Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: the EVOLVE-1 randomized clinical trialQ34663499
Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trialQ34786090
Overall response rate, progression-free survival, and overall survival with targeted and standard therapies in advanced non-small-cell lung cancer: US Food and Drug Administration trial-level and patient-level analysesQ35168766
Systemic therapy of advanced hepatocellular carcinoma: how hopeful should we be?Q36552819
SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma.Q50454368
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Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysisQ59901778
Early detection of liver cancer: diagnosis and managementQ37140022
Design and endpoints of clinical trials in hepatocellular carcinoma.Q37162908
Use of meta-analysis for the validation of surrogate endpoints and biomarkers in cancer trialsQ37614183
Meta-analysis for the association between overall survival and progression-free survival in gastrointestinal stromal tumorQ38283510
A randomized study of KRAS-guided maintenance therapy with bevacizumab, erlotinib or metronomic capecitabine after first-line induction treatment of metastatic colorectal cancer: the Nordic ACT2 trialQ41201235
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL studyQ43691230
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.Q45980006
Progression-free survival is a surrogate for survival in advanced colorectal cancerQ46892021
The validation of surrogate endpoints in meta-analyses of randomized experimentsQ47671365
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 InternationalQ42553662
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)1201-1205
P577publication date2016-10-13
P1433published inBritish Journal of CancerQ326309
P1476titleTTP as a surrogate endpoint in advanced hepatocellular carcinoma treated with molecular targeted therapy: meta-analysis of randomised controlled trials
P478volume115

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cites work (P2860)
Q91742641Axin1 inhibits proliferation, invasion, migration and EMT of hepatocellular carcinoma by targeting miR-650
Q90065478First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials
Q47692343High plasma interleukin-6 levels associated with poor prognosis of patients with advanced hepatocellular carcinoma
Q89927799Ramucirumab after prior sorafenib in patients with advanced hepatocellular carcinoma and elevated alpha-fetoprotein: Japanese subgroup analysis of the REACH-2 trial
Q90288455Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Q47098597Surrogate endpoint for overall survival in assessment of adjuvant therapies after curative treatment for hepatocellular carcinoma: a re-analysis of meta-analyses of individual patients' data