The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain

scientific article published on 7 October 2009

The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EJPAIN.2009.09.001
P698PubMed publication ID19815434
P5875ResearchGate publication ID26881413

P2093author name stringJuan Zhang
Qin Gao
XiaoPing Gu
ZhengLiang Ma
JunHua Wang
FengMei Mei
XiaoFang Zhou
XiaoPing Xia
YanQing Jin
P2860cites workAntinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonistQ24672789
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Developmental and regional expression in the rat brain and functional properties of four NMDA receptorsQ28570615
Neuronal plasticity: increasing the gain in painQ29615421
Quantitative assessment of tactile allodynia in the rat pawQ29617366
Ethical guidelines for investigations of experimental pain in conscious animalsQ29617510
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neuronsQ33907117
Malignant bone pain: pathophysiology and treatmentQ34418896
NMDA receptors as targets for drug action in neuropathic pain.Q34430622
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesiaQ34621303
Recent progress in the pharmacotherapy of cancer painQ34734247
The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications.Q35031245
Spinal and supraspinal contributions to central sensitization in peripheral neuropathyQ36281892
The use of ketamine as adjuvant therapy to control severe painQ37079474
Tumor-evoked hyperalgesia and sensitization of nociceptive dorsal horn neurons in a murine model of cancer painQ37239670
Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiologyQ39415446
Alterations in dorsal horn neurones in a rat model of cancer-induced bone painQ40610103
NMDA receptor blockade in chronic neuropathic pain: a comparison of ketamine and magnesium chlorideQ42554953
Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in ratsQ44264983
Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat.Q45095142
Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia.Q45106035
Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-d-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking techniqueQ45194967
mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivityQ45274101
Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitizationQ46442854
NMDA receptor antagonist treatment at the time of nerve injury prevents injury-induced changes in spinal NR1 and NR2B subunit expression and increases the sensitivity of residual pain behaviours to subsequently administered NMDA receptor antagonistsQ46693237
Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat.Q46937094
NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic miceQ48321527
Ketamine as an adjuvant for treatment of cancer pain in children and adolescentsQ48606176
Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer painQ48664516
Breakthrough pain: characteristics and impact in patients with cancer pain.Q51089873
Pain causes in 200 patients referred to a multidisciplinary cancer pain clinicQ51714386
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.Q52535137
P433issue5
P304page(s)496-502
P577publication date2009-10-07
P1433published inEuropean Journal of PainQ4548992
P1476titleThe role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain
P478volume14

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cites work (P2860)
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