Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

scientific article

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.5056/JNM16203
P8608Fatcat IDrelease_bvkuwekshbbp7pyyzh4aboebie
P932PMC publication ID5503283
P698PubMed publication ID28551943

P50authorJakub FichnaQ22115026
Jakub WłodarczykQ55276377
P2093author name stringMartin Storr
Adam Fabisiak
Natalia Fabisiak
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Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarizationQ28366668
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A potent and selective histamine H4 receptor antagonist with anti-inflammatory propertiesQ28571371
Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonistsQ31119613
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Inhibitory effects of histamine H4 receptor antagonists on experimental colitis in the rat.Q34458021
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Disodium cromoglycate reverses colonic visceral hypersensitivity and influences colonic ion transport in a stress-sensitive rat strainQ35075865
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Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum.Q35761348
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Oral cromolyn sodium in comparison with elimination diet in the irritable bowel syndrome, diarrheic type. Multicenter study of 428 patientsQ71767794
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Combination of allergic factors can worsen diarrheic irritable bowel syndrome: role of barrier defects and mast cellsQ84964787
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Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail)Q36373974
The hypothalamic H1 receptor: a novel therapeutic target for disrupting diurnal feeding rhythm and obesityQ36439307
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal painQ36930795
In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposureQ36979997
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Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysisQ37994513
Histamine and gut mucosal immune regulationQ38167039
Histamine H₄ receptors in the gastrointestinal tract.Q38264340
Novel investigational drugs for constipation-predominant irritable bowel syndrome: a reviewQ38696256
Irritable bowel syndrome and visceral hypersensitivity : risk factors and pathophysiological mechanismsQ38725315
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Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel SyndromeQ39178305
Efficacy and tolerability of ebastine 10 mg plus pseudoephedrine 120 mg in the symptomatic relief of the common coldQ39377696
Inhibition of gastric secretion relieves diarrhea and postprandial urgency associated with irritable bowel syndrome or functional diarrheaQ39436086
The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer.Q40366071
Comparison of the Rome IV and Rome III criteria for IBS diagnosis: A cross-sectional surveyQ40445611
Sensitization of visceral afferents to bradykinin in rat jejunum in vitroQ42480612
Supernatants of irritable bowel syndrome mucosal biopsies impair human colonic smooth muscle contractility.Q42498868
Oral disodium cromoglycate treatment on irritable bowel syndrome: an open study on 101 subjects with diarrheic typeQ42617480
Selective expression of histamine receptors H1R, H2R, and H4R, but not H3R, in the human intestinal tract.Q42844756
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Sensitivity testing in irritable bowel syndrome with rectal capsaicin stimulations: role of TRPV1 upregulation and sensitization in visceral hypersensitivity?Q43420598
Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptorsQ43749173
Neuroimmune interactions in guinea pig stomach and small intestineQ44185420
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome.Q44779671
Histamine-cytokine connection in immunity and hematopoiesisQ45079615
Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome.Q45197721
Self-reported food-related gastrointestinal symptoms in IBS are common and associated with more severe symptoms and reduced quality of lifeQ45840782
Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats.Q45971124
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.Q45974300
Inflammatory bowel disease versus irritable bowel syndrome: a hospital-based, case-control study of disease impact on quality of lifeQ47381227
Stress-induced visceral hypersensitivity to rectal distension in rats: role of CRF and mast cellsQ48548051
Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.Q50584030
Randomised clinical trial: the safety and efficacy of AST-120 in non-constipating irritable bowel syndrome - a double-blind, placebo-controlled study.Q51419778
Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms.Q51660489
Involvement of different receptors in the central and peripheral effects of histamine on intestinal motility in the rat.Q52486402
Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome.Q53622343
Histamine receptor 2 modifies dendritic cell responses to microbial ligands.Q54445895
Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators.Q54513905
P433issue3
P921main subjectirritable bowel syndromeQ838966
P304page(s)341-348
P577publication date2017-05-27
P1433published inJournal of neurogastroenterology and motilityQ26854010
P1476titleTargeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal
P478volume23

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cites work (P2860)
Q101165858Analysis of brain networks and fecal metabolites reveals brain-gut alterations in premenopausal females with irritable bowel syndrome
Q57121405Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2 mice and human cholangiocarcinoma tumorigenesis
Q57116938New treatments and therapeutic targets for IBS and other functional bowel disorders

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