Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

scientific article published on 26 September 2016

Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M116.735142
P932PMC publication ID5114416
P698PubMed publication ID27672209

P50authorLeonid SazanovQ56487620
James A LettsQ56891392
Gianluca DegliespostiQ96088288
P2093author name stringMark Skehel
Karol Fiedorczuk
P2860cites workNatural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I)Q24528261
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GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)Q28214434
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Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilusQ33993467
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2 Preparation and properties of NADH: Cytochrome c oxidoreductase (complex I–III)Q40185520
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Architecture of mammalian respiratory complex I.Q41607512
Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms.Q41631534
Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transferQ42733248
The interaction of quinone and detergent with reaction centers of purple bacteria. I. Slow quinone exchange between reaction center micelles and pure detergent micellesQ42933657
The funnel approach to the precrystallization production of membrane proteinsQ43201259
Bovine heart NADH-ubiquinone oxidoreductase contains one molecule of ubiquinone with ten isoprene units as one of the cofactorsQ43229814
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The complete mitochondrial DNA sequence of the domestic sheep (Ovis aries) and comparison with the other major ovine haplotypeQ47329821
Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase.Q47435178
A low rate of replacement substitutions in two major Ovis aries mitochondrial genomesQ47706275
NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Complementary DNA sequence of the import precursor of the 10 kDa subunit of the flavoprotein fragmentQ48228444
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Slow active/inactive transition of the mitochondrial NADH-ubiquinone reductase.Q52449151
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Binding of detergents and inhibitors to bovine complex I - a novel purification procedure for bovine complex I retaining full inhibitor sensitivityQ58782674
A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex IQ60056624
Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the EnzymeQ63372103
Preparation and properties of NADH: ubiquinone oxidoreductase (complexI), EC 1.6.5.3Q67408366
Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzymeQ67506978
Effect of Ca2+ ions on the slow active/inactive transition of the mitochondrial NADH-ubiquinone reductaseQ67726027
Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductaseQ70494489
An organic phosphorus assay which avoids the use of hazardous perchloric acidQ72932151
Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transitionQ74567714
Characterization of the complete mitochondrial genome sequence of Ujumuqin sheep (Ovis aries)Q86989598
P433issue47
P407language of work or nameEnglishQ1860
P304page(s)24657-24675
P577publication date2016-09-26
P1433published inJournal of Biological ChemistryQ867727
P1476titlePurification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation
P478volume291

Reverse relations

cites work (P2860)
Q30832310Atomic structure of the entire mammalian mitochondrial complex I.
Q47693620Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain
Q99418944Cryo-EM structure of the entire mammalian F-type ATP synthase
Q93051708Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches
Q41600120Functional asymmetry and electron flow in the bovine respirasome
Q90312263Mutations in NDUFS1 Cause Metabolic Reprogramming and Disruption of the Electron Transfer
Q39350533Spatial Organization of Metabolic Enzyme Complexes in Cells
Q92966198Structure and mechanism of mitochondrial proton-translocating transhydrogenase
Q50207901Structure of the Deactive State of Mammalian Respiratory Complex I.
Q93160398Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk
Q52370260Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles: the role of complex I S-nitrosation.

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