NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation.

scientific article published on 15 May 2012

NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1398-9995.2012.02833.X
P932PMC publication ID3401908
P698PubMed publication ID22583069
P5875ResearchGate publication ID224955943

P50authorEmir HadzijusufovicQ38327164
Lukas KennerQ42434147
Peter ValentQ56697676
Barbara PeterQ56872611
Harald HerrmannQ56940149
P2093author name stringM Willmann
S Cerny-Reiterer
W F Pickl
V Yuzbasiyan-Gurkan
T Rülicke
T Thaiwong
K Schuch
P2860cites workMasitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KITQ21142738
Evaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumorsQ33238296
Diagnostic criteria and classification of mastocytosis: a consensus proposalQ33948617
Mast cell tumors in the dog.Q35173798
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.Q35848377
KIT mutations in mastocytosis and their potential as therapeutic targetsQ36576453
Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteriaQ36835061
Mast cells and mastocytosisQ36835143
Generation and characterization of novel canine malignant mast cell line CL1.Q37095268
Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosisQ37247964
Mastocytosis and insect venom allergy: diagnosis, safety and efficacy of venom immunotherapyQ37559690
Tyrosine kinase inhibitors in veterinary medicineQ37592418
Gene expression analysis predicts insect venom anaphylaxis in indolent systemic mastocytosis.Q38504083
Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosisQ39615506
In vitro and in vivo growth-inhibitory effects of cladribine on neoplastic mast cells exhibiting the imatinib-resistant KIT mutation D816V.Q39692224
Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cellsQ39782974
Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumorsQ39958718
Establishment of a novel high-affinity IgE receptor-positive canine mast cell line with wild-type c-kit receptorsQ40034438
Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT.Q40048837
Synergistic antiproliferative effects of KIT tyrosine kinase inhibitors on neoplastic canine mast cells.Q40097396
Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells.Q40188685
Establishment and characterization of a new canine mast cell tumor cell lineQ40773689
Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kitQ40959621
Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasmsQ40973424
Establishment of an immature mast cell line from a patient with mast cell leukemiaQ41296878
How much specific is the association between hymenoptera venom allergy and mastocytosis?Q42457384
Establishment of two dog mastocytoma cell lines in continuous cultureQ42810486
Evaluation of 12- and 24-month survival rates after treatment with masitinib in dogs with nonresectable mast cell tumorsQ42843077
Detection of tryptase in cytoplasmic granules of basophils in patients with chronic myeloid leukemia and other myeloid neoplasmsQ43757354
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kitQ44539087
Cladribine therapy for systemic mastocytosis.Q44559230
Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cellsQ44951894
Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation.Q45977986
Masitinib is safe and effective for the treatment of canine mast cell tumorsQ46341707
Gene expression profile, pathways, and transcriptional system regulation in indolent systemic mastocytosis.Q46418767
PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effectsQ46724516
Mast cell typing: demonstration of a distinct hematopoietic cell type and evidence for immunophenotypic relationship to mononuclear phagocytes.Q50888369
IgE-mediated anaphylaxis to Hippobosca equina in a patient with systemic mastocytosis.Q52700313
Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.Q54194510
Response to interferon alfa-2b in a patient with systemic mastocytosisQ67531413
Mutations in the juxtamembrane domain of c-KIT are associated with higher grade mast cell tumors in dogsQ74815758
P4510describes a project that usesNI-1Q54930542
P433issue7
P921main subjectmast cellQ191989
drug resistanceQ12147416
cell lineQ21014462
P304page(s)858-868
P577publication date2012-05-15
P1433published inAllergyQ2699825
P1476titleNI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation
P478volume67

Reverse relations

cites work (P2860)
Q57174064Comparative oncology: The paradigmatic example of canine and human mast cell neoplasms
Q48104415Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.
Q91732120Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells
Q48120081IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells.
Q35114558Identification of Ponatinib as a potent inhibitor of growth, migration, and activation of neoplastic eosinophils carrying FIP1L1-PDGFRA
Q99409940In vitro effects of histamine receptor 1 antagonists on proliferation and histamine release in canine neoplastic mast cells
Q39159911Oncostatin M is a FIP1L1/PDGFRA-dependent mediator of cytokine production in chronic eosinophilic leukemia
Q55362356Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy.
Q39189820Pharmacological targeting of allergen-specific T lymphocytes
Q48291629The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma.

Q54930542NI-1described by sourceP1343

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