Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets

scientific article published on 2 June 2017

Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EURURO.2017.05.032
P932PMC publication ID6007852
P698PubMed publication ID28583311

P50authorEugene K. ChaQ37839556
Jonathan E RosenbergQ42862184
Nikolaus SchultzQ42862190
Hikmat Al-AhmadieQ42862200
Bernard H BochnerQ42862211
Gopa IyerQ87340030
Dean F BajorinQ88172016
Aditya BagrodiaQ89894166
Irina OstrovnayaQ90067884
David B SolitQ90267706
Guido DalbagniQ90857016
Eugene J PietzakQ124155234
P2093author name stringQiang Li
Michael F Berger
Sumit Isharwal
Ahmet Zehir
Priscilla Baez
Esther N Drill
P2860cites workARID1A mutations in endometriosis-associated ovarian carcinomasQ24610484
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancersQ28257103
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics dataQ28266682
Comprehensive molecular characterization of urothelial bladder carcinomaQ28306864
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trialQ30277192
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burdenQ33568623
Long-term cancer-specific survival in patients with high-risk, non-muscle-invasive bladder cancer and tumour progression: a systematic reviewQ33929786
Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinomaQ34549516
ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors.Q34708383
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladderQ35034441
p53 Status correlates with the risk of recurrence in non-muscle invasive bladder cancers treated with Bacillus Calmette-Guérin: a meta-analysisQ35572365
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular OncologyQ35584856
Mutational inactivation of STAG2 causes aneuploidy in human cancerQ36029045
Genomic Characterization of Upper Tract Urothelial CarcinomaQ36362571
DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'.Q36910861
Histological classification and stage of newly diagnosed bladder cancer in a population-based study from the Northeastern United StatesQ37093851
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing PanelsQ37130135
Recurrence of high-risk bladder cancer: a population-based analysis.Q37171429
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.Q37341453
Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changesQ37649062
The mechanism of action of BCG therapy for bladder cancer--a current perspectiveQ38184849
Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversityQ38297729
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcomeQ39098321
Oncogenic FGFR3 gene fusions in bladder cancerQ39240290
The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation SequencingQ40536461
Genomic characterization of response to chemoradiation in urothelial bladder cancerQ44338887
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urineQ44413803
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregationQ45823928
Mutational context and diverse clonal development in early and late bladder cancer.Q53144252
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
bladder cancerQ504775
P577publication date2017-06-02
P1433published inEuropean UrologyQ15763991
P1476titleNext-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets

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cites work (P2860)
Q92133160A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma
Q90087089A six-gene prognostic model predicts overall survival in bladder cancer patients
Q57167864ARID1A-deficiency in urothelial bladder cancer: No predictive biomarker for EZH2-inhibitor treatment response?
Q103836778Advances in bladder cancer biology and therapy
Q64927304Advances in risk stratification of bladder cancer to guide personalized medicine.
Q91900128Bioinformatics Analysis Identified Key Molecular Changes in Bladder Cancer Development and Recurrence
Q92663356Biomarkers for Bladder Cancer Diagnosis and Surveillance: A Comprehensive Review
Q92487363Biomarkers for platinum sensitivity in bladder cancer: are we there yet?
Q92128606Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches
Q92908635Comparison of 2 new real-time polymerase chain reaction-based urinary markers in the follow-up of patients with non-muscle-invasive bladder cancer
Q89989625Establishment of a novel human cell line retaining the characteristics of the original pancreatic adenocarcinoma, and evaluation of MEK as a therapeutic target
Q58115640Fibroblast growth factor receptors as treatment targets in clinical oncology
Q93044588Functional genetic variant of WW domain containing oxidoreductase gene associated with urothelial cell carcinoma clinicopathologic characteristics and long-term survival
Q91671552Functional network analysis of gene-phenotype connectivity based on pioglitazone
Q91698505GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer
Q91968395Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status
Q57045992Genomic Differences Between "Primary" and "Secondary" Muscle-invasive Bladder Cancer as a Basis for Disparate Outcomes to Cisplatin-based Neoadjuvant Chemotherapy
Q89510134Genomic Landscape of Young-Onset Bladder Cancer and Its Prognostic Implications on Adult Bladder Cancer
Q47404654Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency
Q91401487Genomic and Therapeutic Landscape of Non-muscle-invasive Bladder Cancer
Q92240245High LINC00536 expression promotes tumor progression and poor prognosis in bladder cancer
Q57291360Histone deacetylase inhibition has targeted clinical benefit in ARID1A mutated advanced urothelial carcinoma
Q92448069Immunocytochemistry for ARID1A as a potential biomarker in urine cytology of bladder cancer
Q92059098Impact of RAGE polymorphisms on urothelial cell carcinoma clinicopathologic characteristics and long-term survival
Q91557791Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma
Q89463356Inverted urothelial papilloma and urothelial carcinoma with inverted growth are histologically and molecularly distinct entities
Q58704141Liquid Biopsy Biomarkers in Bladder Cancer: A Current Need for Patient Diagnosis and Monitoring
Q58113597Management of High-grade T1 Urothelial Carcinoma
Q58613925Molecular Characterization of Bladder Cancer
Q90690150Molecular changes during progression from nonmuscle invasive to advanced urothelial carcinoma
Q61842764Mutational landscape of non-muscle-invasive bladder cancer
Q49206807Next-generation sequencing in non-muscle-invasive bladder cancer-a step towards personalized medicine for a superficial bladder tumor
Q49463616Opportunities of next-generation sequencing in non-muscle invasive bladder cancer outcome prediction.
Q57466513P3H4 is correlated with clinicopathological features and prognosis in bladder cancer
Q64262696Prediction tools in non-muscle invasive bladder cancer
Q91401482Predictors of Response to Intravesical Therapy
Q91401470Role of Indoleamine-2,3-Dioxygenase Inhibitors in Salvage Therapy for Non-Muscle Invasive Bladder Cancer
Q90469821SIU-ICUD consultation on bladder cancer: basic science
Q63984741Selection of patients and benefit of immediate radical cystectomy for non-muscle invasive bladder cancer
Q90463014Seminal Vesicle Involvement by Carcinoma In Situ of the Bladder: Clonal Analysis Using Next-Generation Sequencing to Elucidate the Mechanism of Tumor Spread
Q57464869T1 bladder cancer: current considerations for diagnosis and management
Q55443450Telomere Maintenance Mechanisms in Cancer.
Q52724470The evolution of bladder cancer genomics: What have we learned and how can we use it?
Q50072573Toward Personalised Liquid Biopsies for Urothelial Carcinoma: Characterisation of ddPCR and Urinary cfDNA for the Detection of the TERT 228 G>A/T Mutation
Q52602391Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.
Q55427566Unmasking molecular profiles of bladder cancer.
Q88334763Unravelling disparate roles of NOTCH in bladder cancer
Q89817680Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study
Q92837837YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis
Q97067553[Immunotherapies in non-muscle invasive bladder cancer: immunotherapies and NMIBC]

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