| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0303-7207(98)00177-4 |
| P698 | PubMed publication ID | 9922107 |
| P2093 | author name string | R L Rosenfield | |
| K N Qin | |||
| P2860 | cites work | Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells | Q22299409 |
| Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21 | Q24299201 | ||
| Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads | Q24310592 | ||
| Regional mapping of genes encoding human steroidogenic enzymes: P450scc to 15q23-q24, adrenodoxin to 11q22; adrenodoxin reductase to 17q24-q25; and P450c17 to 10q24-q25 | Q24314561 | ||
| The genetic and functional basis of isolated 17,20-lyase deficiency | Q24317633 | ||
| Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis | Q28236461 | ||
| Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis | Q28257443 | ||
| Rat P450(17 alpha) from testis: characterization of a full-length cDNA encoding a unique steroid hydroxylase capable of catalyzing both delta 4- and delta 5-steroid-17,20-lyase reactions | Q28579438 | ||
| Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities | Q28579490 | ||
| Rainbow trout cytochrome P-450c17 (17 alpha-hydroxylase/17,20-lyase). cDNA cloning, enzymatic properties and temporal pattern of ovarian P-450c17 mRNA expression during oogenesis | Q31004512 | ||
| Structure, function and tissue-specific gene expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues | Q34118459 | ||
| Insulin-like growth factor-I enhances luteinizing hormone binding to rat ovarian theca-interstitial cells | Q34258799 | ||
| Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens | Q34368450 | ||
| Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer | Q34454994 | ||
| Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues | Q34588430 | ||
| The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man. | Q34656644 | ||
| Transcriptional regulation of steroid hydroxylase genes by corticotropin | Q35614294 | ||
| Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells | Q35973864 | ||
| Hereditary factors in the Stein-Leventhal syndrome. | Q36076904 | ||
| cDNA cloning and sequence analysis of a chicken gene expressed during the gonadal development and homologous to mammalian cytochrome P-450c17. | Q36427705 | ||
| Assignment of the gene for adrenal P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase) to human chromosome 10. | Q36459982 | ||
| Isolation and characterization of the cDNA encoding the spiny dogfish shark (Squalus acanthias) form of cytochrome P450c17. | Q36702633 | ||
| Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme | Q36711097 | ||
| Characterization of the adrenal cytochrome P450C17 in the hamster, a small animal model for the study of adrenal dehydroepiandrosterone biosynthesis | Q36855745 | ||
| Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells | Q38920754 | ||
| Molecular biology of steroid hormone synthesis | Q39551675 | ||
| Hormonal regulation of androgen production by the Leydig cell | Q40141164 | ||
| 17 alpha-Hydroxylase/17,20-lyase defects. | Q40455009 | ||
| Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome | Q73709707 | ||
| Development of hyperandrogenism during treatment with insulin-like growth factor-I (IGF-I) in female patients with Laron syndrome | Q74332746 | ||
| Congenital adrenal hyperplasia | Q74425274 | ||
| In vitro production of testosterone and androst-4-ene-3, 17-dione in a human ovarian homogenate | Q79030852 | ||
| The polycystic ovary. III. Steroid biosynthesis in normal and polycystic ovarian tissue | Q79338470 | ||
| Kinetic studies on ovarian C-17,20-lyase activity: effect of luteinizing hormone surge | Q93646706 | ||
| Polycystic Ovary Syndrome as a Form of FunctionalOvarian Hyperandrogenism Due to Dysregulation ofAndrogen Secretion* | Q40480667 | ||
| Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome | Q41261033 | ||
| Insulin-like growth factor I and insulin potentiate luteinizing hormone-induced androgen synthesis by rat ovarian thecal-interstitial cells | Q41358032 | ||
| Mutually exclusive interactions of two nuclear orphan receptors determine activity of a cyclic adenosine 3',5'-monophosphate-responsive sequence in the bovine CYP17 gene | Q41364562 | ||
| Adrenal involvement in polycystic ovary syndrome | Q41482764 | ||
| Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17 alpha-hydroxylase and c17,20-lyase) associated with one protein | Q41601083 | ||
| Current concepts of polycystic ovary syndrome | Q41736007 | ||
| Male pseudohermaphroditism due to 17-hydroxylase deficiency | Q41833717 | ||
| Hormonal regulation of messenger ribonucleic acids for P450scc (cholesterol side-chain cleavage enzyme) and P450c17 (17 alpha-hydroxylase/17,20-lyase) in cultured human fetal adrenal cells | Q42079001 | ||
| The role of cytochrome b5 in the biosynthesis of androgens by human P450c17. | Q42281327 | ||
| Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease | Q42472403 | ||
| Effects of inhibin-related peptides and oestradiol on androstenedione and progesterone secretion by bovine theca cells in vitro | Q42481421 | ||
| Transforming growth factor-beta 1 inhibits ovarian androgen production: gene expression, cellular localization, mechanisms(s), and site(s) of action | Q42482429 | ||
| Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome | Q42482499 | ||
| Pituitary-ovarian responses to nafarelin testing in the polycystic ovary syndrome | Q42492169 | ||
| Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries | Q42493096 | ||
| The effects of growth factors and phorbol esters on steroid biosynthesis in isolated human theca interna and granulosa-lutein cells in long term culture | Q42495269 | ||
| Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin. | Q42509680 | ||
| The effect of transforming growth factor-beta on steroidogenesis and expression of key steroidogenic enzymes with a human ovarian thecal-like tumor cell model | Q42517184 | ||
| Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome | Q42519459 | ||
| Inhibin and activin differentially regulate androgen production and 17 alpha-hydroxylase expression in human ovarian thecal-like tumor cells | Q42519716 | ||
| Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism | Q42543416 | ||
| A New Cause of Female Pseudohermaphroditism: Placental Aromatase Deficiency | Q44294999 | ||
| Localization of the human CYP17 gene (cytochrome P450(17 alpha)) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding | Q44531624 | ||
| A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome | Q44942757 | ||
| Evidence that luteinizing hormone-stimulated differentiation of purified ovarian thecal-interstitial cells is mediated by both type I and type II adenosine 3',5'-monophosphate-dependent protein kinases | Q46242311 | ||
| Induction of steroidogenic enzyme genes by insulin and IGF-I in cultured adult human adrenocortical cells. | Q50970429 | ||
| The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. | Q51012842 | ||
| The relationship of insulin insensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries. | Q51599304 | ||
| Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome | Q51607514 | ||
| Detection and functional characterization of the novel missense mutation Y254D in type II 3 beta-hydroxysteroid dehydrogenase (3 beta HSD) gene of a female patient with nonsalt-losing 3 beta HSD deficiency | Q56815767 | ||
| Transcription of the Human Genes for Cytochrome P450scc and P450c17 Is Regulated Differently in Human Adrenal NCI-H295 Cells Than in Mouse Adrenal Y1 Cells | Q57244386 | ||
| The inheritance of polycystic ovarian disease and a possible relationship to premature balding | Q66971823 | ||
| Detection of Functional Ovarian Hyperandrogenism in Women with Androgen Excess | Q67490209 | ||
| Somatomedin-C/insulin-like growth factor I as an enhancer of androgen biosynthesis by cultured rat ovarian cells | Q68128190 | ||
| Inhibitory effect of sandostatin on secretion of luteinising hormone and ovarian steroids in polycystic ovary syndrome | Q68158420 | ||
| Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a 7-basepair duplication in the N-terminal region of the cytochrome P45017 alpha (CYP17) gene | Q68775472 | ||
| Immunolocalization of aromatase, 17 alpha-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary | Q69484612 | ||
| Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture | Q69541169 | ||
| Adrenal androgen hyperresponsiveness to adrenocorticotropin in women with acne and/or hirsutism: adrenal enzyme defects and exaggerated adrenarche | Q70134508 | ||
| Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 alpha-hydroxylase/17,20-lyase) in cultured human granulosa cells | Q70140371 | ||
| Familial polycystic ovaries: a genetic disease? | Q70268706 | ||
| Purification and properties of 17 alpha-hydroxylase from microsomes of pig adrenal: a second C21 side-chain cleavage system | Q70429815 | ||
| The relation between two molecular species of P-450 in adult testis and 17 alpha-hydroxylase and 17,20-lyase activities | Q70900724 | ||
| Immunohistochemical study of steroidogenesis and cell proliferation in polycystic ovarian syndrome | Q71162560 | ||
| The genetics of polycystic ovary syndrome | Q72419361 | ||
| Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17 | Q72530003 | ||
| Evidence for a single gene effect causing polycystic ovaries and male pattern baldness | Q72839906 | ||
| Male pseudohermaphroditism with 17 alpha-hydroxylase deficiency. A case report | Q72871391 | ||
| 17alpha-Hydroxylase gene expression in the bovine ovary: mechanisms regulating expression differ from those in adrenal cells | Q73014441 | ||
| Transcriptional regulation of the bovine CYP17 gene by cAMP | Q73065725 | ||
| Frequency of a polymorphism in the regulatory region of the 17 alpha-hydroxylase-17,20-lyase (CYP17) gene in hyperandrogenic states | Q73307486 | ||
| P433 | issue | 1-2 | |
| P921 | main subject | polycystic ovary syndrome | Q500816 |
| polycystic ovary | Q5547896 | ||
| P304 | page(s) | 111-121 | |
| P577 | publication date | 1998-10-01 | |
| P1433 | published in | Molecular and Cellular Endocrinology | Q1573600 |
| P1476 | title | Role of cytochrome P450c17 in polycystic ovary syndrome | |
| P478 | volume | 145 |
| Q92438064 | Changes in clinical and biochemical characteristics of polycystic ovary syndrome with advancing age |
| Q33733239 | Cryptotanshinone reverses reproductive disturbances in rats with dehydroepiandrosterone-induced polycystic ovary syndrome |
| Q33751592 | Determinants of impaired fasting glucose versus glucose intolerance in polycystic ovary syndrome |
| Q38206261 | Do women with premenopausal-onset rheumatoid arthritis have relative insufficiency or imbalance of adrenocortical steroids? |
| Q35048401 | Effects of electro-acupuncture on ovarian P450arom, P450c17α and mRNA expression induced by letrozole in PCOS rats |
| Q30432819 | Exaggerated 17-hydroxyprogesterone response to intravenous infusions of recombinant human LH in women with polycystic ovary syndrome |
| Q34732880 | Hormones and prostate cancer: current perspectives and future directions |
| Q37355746 | Insulin and hyperandrogenism in women with polycystic ovary syndrome |
| Q33779880 | Is valproate pharmacotherapy associated with polycystic ovaries? |
| Q37198401 | Menstrual health and the metabolic syndrome in adolescents |
| Q35535653 | Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome |
| Q37106561 | Metabolic and hormonal changes induced by pioglitazone in polycystic ovary syndrome: a randomized, placebo-controlled clinical trial |
| Q48054783 | Molecular cloning, characterization expression of P450c17-I and P450c17-II and their functions analysis during the reproductive cycle in males of barfin flounder (Verasper moseri). |
| Q33649402 | Ovarian and adrenal function in polycystic ovary syndrome |
| Q34696198 | Ovarian steroids: the good, the bad, and the signals that raise them |
| Q57473711 | Polycystic Ovary Syndrome: Implication for Drug Metabolism on Assisted Reproductive Techniques-A Literature Review |
| Q51557446 | Serum testosterone levels decrease in middle age in women with the polycystic ovary syndrome. |
| Q28249471 | Structures of human steroidogenic cytochrome P450 17A1 with substrates |
| Q35676497 | The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR-gamma. |
| Q37878799 | Understanding polycystic ovarian syndrome pathogenesis: an updated of its genetic aspects |
| Q89522296 | Use of Bao Gui capsule in treatment of a polycystic ovary syndrome rat model |
| Q48260939 | Vitamin D predictors in polycystic ovary syndrome: a meta-analysis |
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