| P2093 | author name string | Tomas Ganz | |
| | Richard Coffey | |
| P2860 | cites work | Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. | Q54459192 |
| | T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice | Q83613597 |
| | Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin | Q86263513 |
| | The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice | Q21132022 |
| | Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells | Q22253465 |
| | HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression | Q24298843 |
| | Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization | Q24310115 |
| | A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis | Q24310146 |
| | HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis | Q24315610 |
| | Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression | Q24316099 |
| | Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption | Q24320048 |
| | Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2. | Q38764417 |
| | NCOA4 Deficiency Impairs Systemic Iron Homeostasis | Q38802658 |
| | Chaperone protein involved in transmembrane transport of iron | Q38992478 |
| | Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice | Q39173201 |
| | Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse. | Q39622458 |
| | Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis | Q39641301 |
| | An essential cell-autonomous role for hepcidin in cardiac iron homeostasis. | Q39643628 |
| | The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells | Q39787443 |
| | Diferric transferrin regulates transferrin receptor 2 protein stability | Q40524098 |
| | Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs. | Q40792922 |
| | Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus | Q41543544 |
| | The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor | Q41701387 |
| | Both iron deficiency and daily iron supplements increase lipid peroxidation in rats | Q41723105 |
| | Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart | Q41867784 |
| | BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism | Q41871982 |
| | Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. | Q42445804 |
| | Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation | Q42549317 |
| | Regulation of iron absorption in Hfe mutant mice | Q44083659 |
| | L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy | Q44560867 |
| | Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism. | Q51508013 |
| | Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling. | Q51774036 |
| | A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm. | Q52562791 |
| | Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis | Q24324055 |
| | A mouse model of juvenile hemochromatosis | Q24532268 |
| | IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin | Q24568204 |
| | Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats | Q27323133 |
| | Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins | Q28115078 |
| | The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin | Q28115763 |
| | Transferrin receptor is necessary for development of erythrocytes and the nervous system | Q28118509 |
| | Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis | Q28188379 |
| | Identification of erythroferrone as an erythroid regulator of iron metabolism | Q28240988 |
| | Cloning and characterization of a mammalian proton-coupled metal-ion transporter | Q28245045 |
| | Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression | Q28260693 |
| | The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis | Q28264540 |
| | Iron regulates cytoplasmic levels of a novel iron-responsive element-binding protein without aconitase activity | Q28286839 |
| | Identification of the iron-responsive element for the translational regulation of human ferritin mRNA | Q28302958 |
| | Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis | Q28508392 |
| | Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver | Q28509001 |
| | Lack of the bone morphogenetic protein BMP6 induces massive iron overload | Q28510138 |
| | Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus | Q28510247 |
| | Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing | Q28510853 |
| | Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype | Q28510894 |
| | Identification of an intestinal heme transporter | Q28513323 |
| | Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein | Q28571434 |
| | Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis | Q28588832 |
| | A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin | Q28590264 |
| | Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells | Q28594532 |
| | Duodenal reductase activity and spleen iron stores are reduced and erythropoiesis is abnormal in Dcytb knockout mice exposed to hypoxic conditions | Q33455905 |
| | Human macrophage ferroportin biology and the basis for the ferroportin disease | Q33628733 |
| | Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc | Q33702877 |
| | Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin | Q33818360 |
| | The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. | Q33901224 |
| | Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats. | Q34013010 |
| | Circulating non-transferrin-bound iron after oral administration of supplemental and fortification doses of iron to healthy women: a randomized study | Q34056151 |
| | A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. | Q34166480 |
| | Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy | Q34267169 |
| | BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism | Q34293026 |
| | Transferrin receptor 1. | Q34341431 |
| | Erythroferrone contributes to recovery from anemia of inflammation | Q34353734 |
| | Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans | Q34398348 |
| | Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia | Q34489655 |
| | Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution | Q34541622 |
| | Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway | Q34658504 |
| | The labile iron pool: characterization, measurement, and participation in cellular processes(1). | Q34956696 |
| | Abnormal erythroid maturation leads to microcytic anemia in the TSAP6/Steap3 null mouse model | Q35096963 |
| | Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function. | Q35189906 |
| | Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron. | Q35322005 |
| | Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice | Q35483789 |
| | SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis | Q35836771 |
| | Hepcidin in iron overload disorders | Q35847742 |
| | Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2. | Q36067487 |
| | Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice | Q36067702 |
| | Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis | Q36079057 |
| | Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. | Q36119759 |
| | Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese | Q36174536 |
| | Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1. | Q36216669 |
| | ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading | Q36298311 |
| | Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol | Q36366933 |
| | The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development | Q36480866 |
| | The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression | Q36539421 |
| | A cytosolic iron chaperone that delivers iron to ferritin. | Q36826647 |
| | Each member of the poly-r(C)-binding protein 1 (PCBP) family exhibits iron chaperone activity toward ferritin. | Q36929114 |
| | On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver | Q37117562 |
| | Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency | Q37137793 |
| | Mutations in the gene encoding DMT1: clinical presentation and treatment. | Q37604584 |
| | Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis | Q37624591 |
| | Non-transferrin bound iron: a key role in iron overload and iron toxicity | Q37920197 |
| | Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle | Q38255270 |
| | The plasma membrane metal-ion transporter ZIP14 contributes to nontransferrin-bound iron uptake by human β-cells | Q38728231 |
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 12727-12734 | |
| P577 | publication date | 2017-06-14 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Iron homeostasis: An anthropocentric perspective | |
| P478 | volume | 292 | |