review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Anne Houdusse-Juillé | Q15845472 |
Olena Pylypenko | Q41904835 | ||
Hussein Hammich | Q125267436 | ||
P2093 | author name string | I-Mei Yu | |
P2860 | cites work | A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1 | Q24294988 |
A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport | Q24295585 | ||
Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease | Q24295739 | ||
GOLPH3 is essential for contractile ring formation and Rab11 localization to the cleavage site during cytokinesis in Drosophila melanogaster. | Q35160845 | ||
Rab proteins and the compartmentalization of the endosomal system | Q35548944 | ||
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling | Q35642868 | ||
Melanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5a | Q35679335 | ||
The cargo-binding domain regulates structure and activity of myosin 5 | Q35752269 | ||
Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis | Q35779085 | ||
Legionella pneumophila LidA affects nucleotide binding and activity of the host GTPase Rab1 | Q35806017 | ||
Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators | Q35927898 | ||
Targeting Rab GTPases to distinct membrane compartments | Q35936418 | ||
Differential regulation of actin microfilaments by human MICAL proteins | Q36010015 | ||
An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking | Q36155098 | ||
Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3. | Q36266151 | ||
Review series: Rab GTPases and membrane identity: causal or inconsequential? | Q37034278 | ||
Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes | Q37253275 | ||
Griscelli syndrome: a model system to study vesicular trafficking | Q37401438 | ||
Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor | Q37405222 | ||
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting. | Q37599802 | ||
AMPylation is critical for Rab1 localization to vacuoles containing Legionella pneumophila. | Q37631519 | ||
Apical trafficking in epithelial cells: signals, clusters and motors | Q37634760 | ||
Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses | Q24297790 | ||
Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8A resolution | Q24298194 | ||
Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases | Q24299544 | ||
Crystal structure of rab11 in complex with rab11 family interacting protein 2 | Q24299686 | ||
Structural basis for Rab GTPase activation by VPS9 domain exchange factors | Q24303645 | ||
Structural basis of Rab5-Rabaptin5 interaction in endocytosis | Q24304419 | ||
Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes | Q24305088 | ||
Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1 | Q24306419 | ||
Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4. | Q24307945 | ||
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5 | Q24309272 | ||
Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. | Q24310137 | ||
RabGEFs are a major determinant for specific Rab membrane targeting | Q24314408 | ||
Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain | Q24316267 | ||
Large nucleotide-dependent conformational change in Rab28 | Q24316429 | ||
Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA | Q24321974 | ||
Identification and characterization of multiple novel Rab-myosin Va interactions | Q24322633 | ||
The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. | Q24322791 | ||
Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a | Q24336538 | ||
Structural basis for recruitment of RILP by small GTPase Rab7 | Q24529126 | ||
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation | Q24647933 | ||
TIP47 is a key effector for Rab9 localization | Q24683616 | ||
Cellular functions of Rab GTPases at a glance | Q26798421 | ||
Molecular complexes that direct rhodopsin transport to primary cilia | Q26860718 | ||
The cellular and physiological functions of the Lowe syndrome protein OCRL1 | Q26862286 | ||
Bacterial pathogens commandeer Rab GTPases to establish intracellular niches | Q27026776 | ||
Head-to-tail regulation is critical for the in vivo function of myosin V. | Q27310663 | ||
Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening | Q27321208 | ||
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein | Q27325539 | ||
Structural basis of activation and GTP hydrolysis in Rab proteins | Q27617834 | ||
Crystal structures of a Rab protein in its inactive and active conformations | Q27628708 | ||
Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition | Q27630885 | ||
Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A | Q27639792 | ||
Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase | Q27640630 | ||
A Catalytic Coiled Coil: Structural Insights into the Activation of the Rab GTPase Sec4p by Sec2p | Q27643770 | ||
Structure of the small GTPase Rab27b shows an unexpected swapped dimer | Q27646174 | ||
The Structural Basis for Activation of the Rab Ypt1p by the TRAPP Membrane-Tethering Complexes | Q27650964 | ||
Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases | Q27652590 | ||
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity | Q27658919 | ||
Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA | Q27660007 | ||
Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1) | Q27662147 | ||
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b | Q27663583 | ||
Protein LidA from Legionella is a Rab GTPase supereffector | Q27675125 | ||
The activation cycle of Rab GTPase Ypt32 reveals structural determinants of effector recruitment and GDI binding | Q27675208 | ||
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate | Q27675441 | ||
Catalytic mechanism of a mammalian Rab⋅RabGAP complex in atomic detail | Q27675470 | ||
Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB | Q27675735 | ||
Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP | Q27677378 | ||
Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State | Q27678042 | ||
Structural basis of cargo recognitions for class V myosins | Q27678783 | ||
The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism | Q27678890 | ||
Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB | Q27680081 | ||
Structural basis of myosin V Rab GTPase-dependent cargo recognition | Q27680629 | ||
Structures of PI4KIII complexes show simultaneous recruitment of Rab11 and its effectors | Q27684007 | ||
Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5 | Q27684443 | ||
Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins | Q27686798 | ||
Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11 | Q27701769 | ||
Coordination of Rab8 and Rab11 in primary ciliogenesis | Q27967674 | ||
The roles of evolutionarily conserved functional modules in cilia-related trafficking | Q28000150 | ||
BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor | Q28117259 | ||
The guanine nucleotide-binding switch in three dimensions | Q28131710 | ||
VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion. | Q37674312 | ||
Rab GEFs and GAPs | Q37751479 | ||
Structure-function relationships of the G domain, a canonical switch motif | Q37889983 | ||
Illuminating the functional and structural repertoire of human TBC/RABGAPs. | Q37976530 | ||
Structural biology of Arf and Rab GTPases' effector recruitment and specificity | Q38127799 | ||
Kinetics of interaction of Rab5 and Rab7 with nucleotides and magnesium ions | Q38353916 | ||
Structures of Ras superfamily effector complexes: What have we learnt in two decades? | Q38399347 | ||
Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation | Q38830831 | ||
The lipid kinase PI4KIIIβ is highly expressed in breast tumors and activates Akt in cooperation with Rab11a | Q38981564 | ||
Molecular control of Rab activity by GEFs, GAPs and GDI. | Q39068332 | ||
Microvillus inclusion disease: loss of Myosin vb disrupts intracellular traffic and cell polarity. | Q39076973 | ||
Multivalent Rab interactions determine tether-mediated membrane fusion | Q39182367 | ||
Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment | Q39760408 | ||
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules | Q39776544 | ||
Rab6 regulates transport and targeting of exocytotic carriers | Q40097541 | ||
Multiple regions contribute to membrane targeting of Rab GTPases | Q40488536 | ||
Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1. | Q40831502 | ||
Rab35 GTPase Triggers Switch-like Recruitment of the Lowe Syndrome Lipid Phosphatase OCRL on Newborn Endosomes | Q40847509 | ||
bMERB domains are bivalent Rab8 family effectors evolved by gene duplication | Q41111601 | ||
Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins | Q41898316 | ||
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation | Q41940031 | ||
The motor function of Drosophila melanogaster myosin-5 is activated by calcium and cargo-binding protein dRab11. | Q41998305 | ||
A molecular network for de novo generation of the apical surface and lumen | Q42116509 | ||
Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth | Q42175750 | ||
A pull-down procedure for the identification of unknown GEFs for small GTPases | Q42730859 | ||
Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation | Q42906968 | ||
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes | Q45345750 | ||
Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis. | Q45998530 | ||
Active diffusion positions the nucleus in mouse oocytes | Q48583286 | ||
The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily. | Q48745906 | ||
Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains. | Q50335798 | ||
Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation. | Q50336184 | ||
Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains | Q57278410 | ||
GTPase activity of Rab5 acts as a timer for endocytic membrane fusion | Q59097967 | ||
'Rab'ing up endosomal membrane transport | Q77614150 | ||
Rab GTPases at a glance | Q81566767 | ||
Membrane Trafficking: An Endosome Tether Meets a Rab and Collapses | Q88623657 | ||
Rab GTPases as coordinators of vesicle traffic | Q28131746 | ||
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages | Q28138534 | ||
Evolution of the Rab family of small GTP-binding proteins | Q28204091 | ||
Phosphatidylinositol 4-kinasebeta is critical for functional association of rab11 with the Golgi complex | Q28242748 | ||
Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination | Q28485632 | ||
Modulation of Rab GTPase function by a protein phosphocholine transferase | Q28485636 | ||
An actin-dependent mechanism for long-range vesicle transport | Q28506739 | ||
The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting | Q28508183 | ||
cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein | Q28569766 | ||
Crystal structure of the Rab binding domain of OCRL1 in complex with Rab8 and functional implications of the OCRL1/Rab8 module for Lowe syndrome | Q29543937 | ||
Role of Rab GTPases in membrane traffic and cell physiology | Q29616548 | ||
Rabs and their effectors: achieving specificity in membrane traffic | Q29619989 | ||
Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling | Q30476697 | ||
Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease | Q30581661 | ||
Rab11-FIP2 interaction with MYO5B regulates movement of Rab11a-containing recycling vesicles | Q30582688 | ||
A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination | Q30584664 | ||
An endosomal tether undergoes an entropic collapse to bring vesicles together | Q30831126 | ||
Oxidation of F-actin controls the terminal steps of cytokinesis | Q30840206 | ||
Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis | Q33589995 | ||
Thousands of rab GTPases for the cell biologist | Q34055251 | ||
Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes. | Q34109207 | ||
Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5. | Q34120152 | ||
Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions | Q34133114 | ||
Multiple factors contribute to inefficient prenylation of Rab27a in Rab prenylation diseases | Q34225670 | ||
Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease | Q34328378 | ||
Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library | Q34368280 | ||
Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis | Q34370824 | ||
Toward a comprehensive map of the effectors of rab GTPases | Q34513353 | ||
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. | Q34549396 | ||
Rab GTPase prenylation hierarchy and its potential role in choroideremia disease | Q35072549 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
P433 | issue | 1-2 | |
P921 | main subject | enzyme | Q8047 |
peptide | Q172847 | ||
transport protein | Q2111029 | ||
P304 | page(s) | 22-48 | |
P577 | publication date | 2017-07-07 | |
2018-03-04 | |||
P1433 | published in | Small GTPases (journal) | Q15709529 |
P1476 | title | Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity | |
P478 | volume | 9 |
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