| scholarly article | Q13442814 |
| P50 | author | Andrew Paul McMahon | Q21165205 |
| P2093 | author name string | Benjamin D Humphreys | |
| Petra Sipilä | |||
| Kip A West | |||
| Benoit St-Jacques | |||
| Steven L Fabian | |||
| Anjali N Rao | |||
| Radostin R Penchev | |||
| P2860 | cites work | Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes | Q24297796 |
| Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney | Q24313237 | ||
| PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate | Q24683266 | ||
| TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis | Q27008239 | ||
| Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation | Q28139169 | ||
| Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling | Q28141240 | ||
| Hedgehog signaling in animal development: paradigms and principles | Q28208463 | ||
| Pallister-Hall syndrome phenotype in mice mutant for Gli3 | Q28215920 | ||
| Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo | Q28237073 | ||
| Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926) | Q28248383 | ||
| GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis | Q28505774 | ||
| GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells | Q28513713 | ||
| GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome | Q55670535 | ||
| The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors | Q73954844 | ||
| Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor | Q80694420 | ||
| Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs | Q28588215 | ||
| Macrophage Wnt7b is critical for kidney repair and regeneration | Q28594469 | ||
| Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer | Q29547558 | ||
| Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder | Q30540440 | ||
| Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis | Q33556248 | ||
| Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis | Q33771703 | ||
| Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract | Q33812943 | ||
| Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells | Q33815303 | ||
| Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse. | Q34082587 | ||
| Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia | Q34157874 | ||
| Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans | Q34245363 | ||
| Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine | Q34418477 | ||
| Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis. | Q34511187 | ||
| TGF-beta signaling in renal disease | Q34869314 | ||
| Methylation determines fibroblast activation and fibrogenesis in the kidney | Q35019643 | ||
| Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells | Q35034972 | ||
| Hedgehog/Ras interactions regulate early stages of pancreatic cancer | Q35127709 | ||
| Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells | Q36072093 | ||
| Post-translational processing and renal expression of mouse Indian hedgehog | Q36851317 | ||
| Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans | Q36890842 | ||
| Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis | Q37110115 | ||
| Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury | Q37591248 | ||
| Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). | Q37633966 | ||
| Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals | Q37677356 | ||
| Control of mammalian kidney development by the Hedgehog signaling pathway | Q37821327 | ||
| The origin of interstitial myofibroblasts in chronic kidney disease | Q37839779 | ||
| Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? | Q37849269 | ||
| Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells | Q38360694 | ||
| Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice | Q39759405 | ||
| A paracrine requirement for hedgehog signalling in cancer | Q39946287 | ||
| Functional antagonists of sonic hedgehog reveal the importance of the N terminus for activity. | Q40917658 | ||
| Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells | Q42165194 | ||
| Sonic hedgehog controls stem cell behavior in the postnatal and adult brain | Q42699442 | ||
| Renovascular disease, microcirculation, and the progression of renal injury: role of angiogenesis | Q42715235 | ||
| Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells | Q42728761 | ||
| Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. | Q46801058 | ||
| Activation of Erk1/2 and Akt following unilateral ureteral obstruction. | Q50651014 | ||
| Renal regeneration: reiterating a developmental paradigm. | Q52174228 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1441-1453 | |
| P577 | publication date | 2012-02-17 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | Hedgehog-Gli pathway activation during kidney fibrosis | |
| P478 | volume | 180 |
| Q57282418 | A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition |
| Q47706146 | A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies |
| Q48104246 | AT2 R deficiency mediated podocyte loss via activation of ectopic hedgehog interacting protein (Hhip) gene expression |
| Q41059218 | Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway |
| Q90707336 | Arsenic trioxide and curcumin attenuate cisplatin-induced renal fibrosis in rats through targeting Hedgehog signaling |
| Q57813158 | BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair |
| Q37609662 | Cell-specific translational profiling in acute kidney injury |
| Q36763871 | Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis |
| Q38011541 | Crosstalk between TGF-β and hedgehog signaling in cancer. |
| Q41088301 | Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development |
| Q94555069 | Development of a new macrophage-specific TRAP mouse (MacTRAP) and definition of the renal macrophage translational signature |
| Q38824254 | Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog |
| Q47139581 | Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β1 and Shh Signalling |
| Q48341303 | Disruption of the Hedgehog signaling pathway in inflammatory bowel disease fosters chronic intestinal inflammation |
| Q38995182 | Does Renal Repair Recapitulate Kidney Development? |
| Q26748338 | Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases |
| Q38710580 | Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? |
| Q36548726 | Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages |
| Q89589648 | Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype |
| Q99584589 | Exploring Key Challenges of Understanding the Pathogenesis of Kidney Disease in Bardet-Biedl Syndrome |
| Q38391570 | Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression |
| Q48224258 | Fibroblast-Specific β-catenin Signaling Dictates the Outcome of AKI. |
| Q55443022 | Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition. |
| Q28392538 | Genetic tools for identifying and manipulating fibroblasts in the mouse |
| Q64103220 | Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease |
| Q38821608 | Gli1+ Pericyte Loss Induces Capillary Rarefaction and Proximal Tubular Injury |
| Q27468911 | HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2 |
| Q38845233 | Hedgehog Gli signalling in kidney fibrosis |
| Q52589070 | Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes. |
| Q26766578 | Hedgehog Signaling in Pancreatic Fibrosis and Cancer |
| Q38718042 | Hedgehog pathway plays a vital role in HIV-induced epithelial-mesenchymal transition of podocyte. |
| Q37056427 | Hedgehog signaling in neonatal and adult lung. |
| Q36237115 | Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury. |
| Q42376280 | Hesperetin alleviates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro |
| Q26852800 | Host responses in tissue repair and fibrosis |
| Q47139383 | Human induced pluripotent stem cell-derived mesenchymal stem cells prevent adriamycin nephropathy in mice |
| Q93336636 | Indian Hedgehog links obesity to development of hepatocellular carcinoma |
| Q35882616 | Inflammatory PAF Receptor Signaling Initiates Hedgehog Signaling and Kidney Fibrogenesis During Ethanol Consumption |
| Q99567371 | Integrative microRNA and mRNA expression profiling in acute aristolochic acid nephropathy in mice |
| Q35118918 | Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1 |
| Q89472339 | Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells |
| Q35695329 | Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development |
| Q26796622 | Kick it up a notch: Notch signaling and kidney fibrosis |
| Q35770285 | Kidney Regeneration: Lessons from Development |
| Q37364008 | Matrix Producing Cells in Chronic Kidney Disease: Origin, Regulation, and Activation. |
| Q38293779 | Mechanisms of initiation and progression of intestinal fibrosis in IBD. |
| Q51758759 | Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response. |
| Q38909043 | MicroRNA-370 Attenuates Hepatic Fibrogenesis by Targeting Smoothened |
| Q35759059 | Molecular Markers of Tubulointerstitial Fibrosis and Tubular Cell Damage in Patients with Chronic Kidney Disease |
| Q47263487 | Mouse Metanephric Mesenchymal Cell-Derived Angioblasts Undergo Vasculogenesis in Three-Dimensional Culture. |
| Q35837331 | Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE. |
| Q27022840 | Myofibroblasts |
| Q37262528 | Myofibroblasts in Fibrotic Kidneys |
| Q39567618 | New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis |
| Q38309155 | New insights into lung development and diseases: the role of microRNAs. |
| Q93000193 | Nrf2-Heme Oxygenase-1 Attenuates High-Glucose-Induced Epithelial-to-Mesenchymal Transition of Renal Tubule Cells by Inhibiting ROS-Mediated PI3K/Akt/GSK-3β Signaling |
| Q39242453 | Origin and Function of the Renal Stroma in Health and Disease |
| Q91876572 | Origin and role of hepatic myofibroblasts in hepatocellular carcinoma |
| Q55236600 | Pathway crosstalk enables cells to interpret TGF-β duration. |
| Q89243186 | Pericytes in the renal vasculature: roles in health and disease |
| Q34899171 | Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis. |
| Q36040432 | Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis |
| Q64100425 | Profibrotic epithelial phenotype: a central role for MRTF and TAZ |
| Q38988806 | Progression of chronic kidney disease: too much cellular talk causes damage |
| Q90182405 | Proximal Tubule Translational Profiling during Kidney Fibrosis Reveals Proinflammatory and Long Noncoding RNA Expression Patterns with Sexual Dimorphism |
| Q38359455 | Renal allograft fibrosis: biology and therapeutic targets |
| Q35061485 | Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis |
| Q26743373 | Role of Hedgehog Signaling Pathway in NASH |
| Q37133793 | Role of microRNAs in lung development and pulmonary diseases |
| Q26823066 | Roles for Hedgehog signaling in adult organ homeostasis and repair |
| Q40173535 | Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis |
| Q39030259 | Signaling Crosstalk between Tubular Epithelial Cells and Interstitial Fibroblasts after Kidney Injury |
| Q37419990 | Six2creFrs2α knockout mice are a novel model of renal cystogenesis |
| Q34260026 | Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury |
| Q38873492 | Sonic hedgehog signaling in kidney fibrosis: a master communicator |
| Q34431127 | Sonic hedgehog signaling in the lung. From development to disease |
| Q44537770 | TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases. |
| Q50694421 | Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice. |
| Q89723568 | Targeting the progression of chronic kidney disease |
| Q26796637 | The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury |
| Q47112797 | The Hedgehog Signaling Pathway Emerges as a Pathogenic Target |
| Q93078960 | The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis |
| Q99590766 | The efficacy of taking traditional Chinese medicine orally in renal interstitial fibrosis: A protocol for a systematic review and meta-analysis |
| Q37607546 | The fate of the primary cilium during myofibroblast transition |
| Q39433671 | Tracking Adventitial Fibroblast Contribution to Disease: A Review of Current Methods to Identify Resident Fibroblasts |
| Q38740036 | Transforming growth factor-β1 stimulates hedgehog signaling to promote epithelial-mesenchymal transition after kidney injury |
| Q34103505 | Translational profiles of medullary myofibroblasts during kidney fibrosis. |
| Q38134341 | Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease. |
| Q36277100 | Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease |
| Q37119898 | Wnt4/β-catenin signaling in medullary kidney myofibroblasts |
Search more.