The JAK2-Akt-glycogen synthase kinase-3β signaling pathway is involved in toll-like receptor 2-induced monocyte chemoattractant protein-1 regulation

scientific article published on 3 January 2012

The JAK2-Akt-glycogen synthase kinase-3β signaling pathway is involved in toll-like receptor 2-induced monocyte chemoattractant protein-1 regulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2012.741
P932PMC publication ID3493083
P698PubMed publication ID22218715
P5875ResearchGate publication ID51983431

P2093author name stringJin-Sik Kim
Yoe-Sik Bae
Suk-Hwan Baek
Byung-Rho Chin
Dae-Weon Park
Tae-Whal Jeong
Hyung-Kyoung Lee
P2860cites workApolipoprotein CIII Induces Monocyte Chemoattractant Protein-1 and Interleukin 6 Expression Via Toll-Like Receptor 2 Pathway in Mouse Adipocytes: RetractedQ38860543
IL-6/gp130/STAT3 signaling axis in cancer and the presence of in-frame gp130 somatic deletions in inflammatory hepatocellular tumorsQ39986650
Toll-like receptor 9-stimulated monocyte chemoattractant protein-1 is mediated via JNK-cytosolic phospholipase A2-ROS signalingQ40067160
Cilostazol attenuates MCP-1 and MMP-9 expression in vivo in LPS-administrated balloon-injured rabbit aorta and in vitro in LPS-treated monocytic THP-1 cellsQ40129907
Janus kinase 2 is involved in lipopolysaccharide-induced activation of macrophagesQ40657235
Resveratrol inhibits foam cell formation via NADPH oxidase 1- mediated reactive oxygen species and monocyte chemotactic protein-1.Q41837091
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.Q42431545
Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathwaysQ44709178
Selective regulation of interleukin-10 production via Janus kinase pathway in murine conventional dendritic cellsQ46053579
The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signalsQ47265822
The specific role of chemokines in atherosclerosis.Q53555491
Atherosclerotic lesion development and Toll like receptor 2 and 4 responsivenessQ59981259
Activation of PKC-epsilon and ERK1/2 participates in shear-induced endothelial MCP-1 expression that is repressed by nitric oxideQ73294016
High expression level of Toll-like receptor 2 on monocytes is an important risk factor for arteriosclerotic diseaseQ84574286
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimerQ24318972
Requirement of TLR2-mediated signaling for the induction of IL-15 gene expression in human monocytic cells by HSV-1Q24336181
Pathogen recognition and innate immunityQ27861084
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic eventsQ33318184
Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses.Q33745132
Modulation of atherosclerosis in mice by Toll-like receptor 2Q34063165
Chemokines in atherosclerosis: an updateQ34656531
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticlesQ35001472
Toll-like receptor signalingQ35189960
Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.Q36459911
Mechanisms of disease: Toll-like receptors in cardiovascular diseaseQ36891895
Protein kinase D1 is essential for MyD88-dependent TLR signaling pathwayQ37195948
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumoursQ37224637
Toll-like receptors as targets in chronic liver diseasesQ37469924
Therapeutic targeting of chemokine interactions in atherosclerosisQ37684793
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activationQ37856309
Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritisQ37859678
Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2.Q37860795
P433issue4
P921main subjecttoll-like receptorQ408004
P304page(s)1063-1067
P577publication date2012-01-03
P1433published inMolecular Medicine ReportsQ26842180
P1476titleThe JAK2-Akt-glycogen synthase kinase-3β signaling pathway is involved in toll-like receptor 2-induced monocyte chemoattractant protein-1 regulation
P478volume5

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cites work (P2860)
Q37336070Chlamydia pneumoniae infection promotes vascular smooth muscle cell migration through a Toll-like receptor 2-related signaling pathway
Q43106827Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activation
Q36319698Role of MCP-1 in alcohol-induced aggressiveness of colorectal cancer cells

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