Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

scientific article published on December 8, 2011

Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BBAMCR.2011.10.014
P953full work available online athttps://api.elsevier.com/content/article/PII:S0167488911003223?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0167488911003223?httpAccept=text/xml
https://doi.org/10.1016/j.bbamcr.2011.10.014
P698PubMed publication ID22178132
P5875ResearchGate publication ID51896708

P50authorSeoungwoo ShinQ61152717
P2093author name stringJeen-Woo Park
Sung Youl Kim
P2860cites workRole of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagyQ37075287
Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cellsQ38339714
Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivoQ39848176
Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis.Q39890141
Autophagy inhibition enhances anthocyanin-induced apoptosis in hepatocellular carcinomaQ39947723
Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoanilineQ39957310
Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagyQ40062826
Cancer statistics, trends, and multiple primary cancer analyses from the Surveillance, Epidemiology, and End Results (SEER) ProgramQ40251202
Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cellsQ40272756
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathwayQ40789651
MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cellsQ45872881
Nutrient sensing in the mTOR/S6K1 signalling pathwayQ48235664
Autophagy and p70S6 kinaseQ52670758
Autophagy and cancerQ56772657
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
Autophagy: molecular machinery for self-eatingQ24678361
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Q27824772
Autophagy in the Pathogenesis of DiseaseQ27860558
The phosphoinositide 3-kinase pathwayQ27860738
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1Q28245694
Pharmacology of oleanolic acid and ursolic acidQ28292594
The protein kinase B/Akt signalling pathway in human malignancyQ28645742
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
Development by self-digestion: molecular mechanisms and biological functions of autophagyQ29547880
Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cellsQ29614181
Exploiting the PI3K/AKT pathway for cancer drug discoveryQ29615120
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progressionQ29617473
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesisQ29617725
Autophagy in health and disease: a double-edged swordQ29618103
Role of autophagy in cancerQ29620348
Potential therapeutic applications of autophagyQ29622862
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosisQ29622875
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesiclesQ32046208
Anti-androgens and other hormonal therapies for prostate cancerQ33800968
Chemotherapy for advanced hormone refractory prostate cancerQ33800983
Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxideQ34144553
Molecular targets of dietary agents for prevention and therapy of cancerQ34505253
Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNKQ34568521
How death shapes life during developmentQ34931816
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.Q35189872
Molecular pathways to prostate cancerQ35591632
Autophagosomes: biogenesis from scratch?Q36174994
PI3K/Akt/mTOR pathway as a target for cancer therapyQ36227186
The role of autophagy in cancer development and response to therapy.Q36251939
The Akt-mTOR tango and its relevance to cancerQ36260264
Autophagy signaling and the cogwheels of cancerQ36549487
Autophagy in cancer: good, bad, or both?Q36612549
Regulation of macroautophagy by mTOR and Beclin 1 complexesQ36967476
The roles of therapy-induced autophagy and necrosis in cancer treatmentQ37038235
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
autophagyQ288322
P304page(s)451-457
P577publication date2011-12-08
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleAutophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells
P478volume1823

Reverse relations

cites work (P2860)
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Q36556245Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells
Q26823022Chinese medicines induce cell death: the molecular and cellular mechanisms for cancer therapy
Q93164897Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy
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Q49565076Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells
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Q90232344Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells

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