Dynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1.

scientific article

Dynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VACCINE.2009.10.154
P698PubMed publication ID20510741
P5875ResearchGate publication ID44638251

P50authorYuetsu TanakaQ66386565
P2093author name stringYoshio Koyanagi
Naoko Misawa
Kei Sato
Mamoru Ito
Chuanyi Nie
P2860cites workCD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) miceQ24669724
NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cellsQ28207942
Humanized NOD/SCID/IL2Rgamma(null) mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesisQ28756080
The dendritic cell system and its role in immunogenicityQ29619870
Human immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection.Q33816889
The human immunodeficiency virus: infectivity and mechanisms of pathogenesisQ34049376
Rodent models for HIV-1 infection and diseaseQ35713541
Isoforms of the CD45 common leukocyte antigen family: markers for human T-cell differentiationQ35868451
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infectionQ36229666
Constant mean viral copy number per infected cell in tissues regardless of high, low, or undetectable plasma HIV RNA.Q36369965
Experimental models to study development and function of the human immune system in vivoQ36385564
Modulation of human immunodeficiency virus type 1 infectivity through incorporation of tetraspanin proteinsQ36424527
T cell immune responses to HIV-1.Q36664081
Cellular responses to viral infection in humans: lessons from Epstein-Barr virus.Q36766875
The SCID-hu mouse: a small animal model for HIV infection and pathogenesisQ37357883
Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouseQ37517923
Interleukin-4-transgenic hu-PBL-SCID mice: a model for the screening of antiviral drugs and immunotherapeutic agents against X4 HIV-1 virusesQ39320904
Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5.Q39551157
Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responsesQ39580500
Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice modelQ40656354
Humanized mice: are we there yet?Q42972285
In HIV-1 pathogenesis the die is cast during primary infectionQ43716538
Thymus-independent T-cell differentiation in vitroQ43875695
A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responsesQ43939988
Human immunodeficiency virus infection of human-PBL-SCID miceQ45853273
Development of a human adaptive immune system in cord blood cell-transplanted miceQ47819239
Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cellsQ49051187
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.Q53888112
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.Q55487007
Identification of human T-lymphoid progenitor cells in CD34+CD38low and CD34+CD38+ subsets of human cord blood and bone marrow cells using NOD-SCID fetal thymus organ culturesQ58125714
Infection of the SCID-hu mouse by HIV-1Q67985380
A unified theory of central tolerance in the thymusQ83036352
P407language of work or nameEnglishQ1860
P921main subjectlymphocyteQ715347
HIVQ15787
P304page(s)B32-7
P577publication date2010-05-01
P1433published inVaccineQ7907941
P1476titleDynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1.
P478volume28 Suppl 2

Reverse relations

cites work (P2860)
Q34352429APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model
Q38043556Animal models in virus research: their utility and limitations
Q38765734Anti-HIV-1 potency of the CRISPR/Cas9 system insufficient to fully inhibit viral replication
Q37195155Can humanized mice reflect the complex pathobiology of HIV-associated neurocognitive disorders?
Q33577361Current advances in humanized mouse models
Q34474320Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis
Q87056737Development of human B cells and antibodies following human hematopoietic stem cell transplantation to Rag2(-/-)γc(-/-) mice
Q46246548Experimental adaptive evolution of SIVcpz to pandemic HIV-1 using a humanized mouse model
Q36056241Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.
Q64104899HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice
Q35067233HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo
Q33699581HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation
Q37676228HIV-1 immunopathogenesis in humanized mouse models
Q50146682Humanized Mice as Unique Tools for Human-Specific Studies
Q38787325Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.
Q37111994Humanized mice for immune system investigation: progress, promise and challenges
Q40548525Humanized mouse as an appropriate model for accelerated global HIV research and vaccine development: current trend
Q37089865Humanized mouse models of HIV infection
Q37254488Humoral immunity in humanized mice: a work in progress
Q37467601Improved B cell development in humanized NOD-scid IL2Rγnull mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3
Q36601983Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary
Q34920166Mice with human immune system components as in vivo models for infections with human pathogens
Q35921136Modeling HIV-associated neurocognitive disorders in mice: new approaches in the changing face of HIV neuropathogenesis
Q27014786New generation humanized mice for virus research: comparative aspects and future prospects
Q37900419The mouse is out of the bag: insights and perspectives on HIV-1-infected humanized mouse models
Q35206268The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment
Q35943823Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice

Search more.