scholarly article | Q13442814 |
P356 | DOI | 10.1002/JCB.24006 |
P698 | PubMed publication ID | 22134836 |
P2093 | author name string | Maria Zannis-Hadjopoulos | |
Domenic Di Paola | |||
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Replication licensing and cancer--a fatal entanglement? | Q24644766 | ||
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication | Q24647097 | ||
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing | Q24647856 | ||
Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells | Q24679451 | ||
PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins | Q24811726 | ||
14-3-3 proteins function in the initiation and elongation steps of DNA replication in Saccharomyces cerevisiae | Q27929787 | ||
The 14-3-3 protein homologues from Saccharomyces cerevisiae, Bmh1p and Bmh2p, have cruciform DNA-binding activity and associate in vivo with ARS307. | Q27932007 | ||
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks | Q27934889 | ||
DNA replication in eukaryotic cells | Q28131747 | ||
Ku80 binds to human replication origins prior to the assembly of the ORC complex | Q28252302 | ||
Cdc7 inhibition reveals a p53-dependent replication checkpoint that is defective in cancer cells | Q28286189 | ||
PCNA, the maestro of the replication fork | Q28303101 | ||
Right place, right time, and only once: replication initiation in metazoans | Q30438278 | ||
The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed mammalian cells | Q31112880 | ||
Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis | Q39964608 | ||
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. | Q40035632 | ||
Initiation points for DNA replication in nontransformed and simian virus 40-transformed Chinese hamster lung cells | Q40089783 | ||
A novel biomarker for the detection of esophageal adenocarcinoma | Q40255053 | ||
Differentially active origins of DNA replication in tumor versus normal cells | Q40278758 | ||
Oncogenic activity of Cdc6 through repression of the INK4/ARF locus | Q40298342 | ||
Overexpression of ORC subunits and increased ORC-chromatin association in transformed mammalian cells | Q40373347 | ||
Decreased origin usage and initiation of DNA replication in haploinsufficient HCT116 Ku80+/- cells | Q40398220 | ||
Nuclear organization of DNA replication in primary mammalian cells. | Q40445454 | ||
Spatio-temporal organization of DNA replication in murine embryonic stem, primary, and immortalized cells. | Q40456048 | ||
Initiation sites for human DNA replication at a putative ribulose-5-phosphate 3-epimerase gene | Q40538381 | ||
Alteration of in vivo DNA synthesis in the alpha globin locus of chick embryo fibroblasts due to in vivo activity of Rous sarcoma virus pp60src | Q40632356 | ||
Immortalization of human WI38 cells is associated with differential activation of the c-myc origins | Q40786654 | ||
The search for origins of DNA replication | Q40872037 | ||
DNA content and chromatin texture of benzo[a]pyrene-transformed human breast epithelial cells as assessed by image analysis | Q41003102 | ||
Eucaryotic DNA: organization of the genome for replication | Q41891888 | ||
DNA replication regulation protein Mcm7 as a marker of proliferation in prostate cancer | Q42150330 | ||
Expression and heterodimer-binding activity of Ku70 and Ku80 in human non-melanoma skin cancer | Q42491290 | ||
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis | Q42491680 | ||
Nuclease S1 sensitive sites in parental DNA of cold- and temperature-sensitive mammalian cells | Q42825101 | ||
Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation | Q42834335 | ||
Cell type-specific responses of human cells to inhibition of replication licensing | Q43219572 | ||
Is there a pre-RC checkpoint that cancer cells lack? | Q46760534 | ||
Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. | Q46949073 | ||
Identification and functional analysis of a human homologue of the monkey replication origin ors8. | Q50724389 | ||
Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing. | Q51834619 | ||
Ku is involved in cell growth, DNA replication and G1-S transition. | Q53500086 | ||
Identification of novel initiation sites for human DNA replication around ARSH1, a previously characterized yeast replicator. | Q54735331 | ||
Control of DNA replication and its potential clinical exploitation. | Q55039971 | ||
Chaotic license for genetic instability and cancer | Q56928083 | ||
Deletion of the cruciform binding domain in CBP/14-3-3 displays reduced origin binding and initiation of DNA replication in budding yeast | Q33281965 | ||
Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin | Q33396223 | ||
Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation | Q33523235 | ||
Hypermethylated 14-3-3-sigma and ESR1 gene promoters in serum as candidate biomarkers for the diagnosis and treatment efficacy of breast cancer metastasis | Q33582678 | ||
14-3-3gamma induces oncogenic transformation by stimulating MAP kinase and PI3K signaling | Q33632327 | ||
Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells | Q33693748 | ||
Association of human origin recognition complex 1 with chromatin DNA and nuclease-resistant nuclear structures | Q33890737 | ||
A p53-dependent checkpoint pathway prevents rereplication | Q34533175 | ||
Utilization of the same DNA replication origin by human cells of different derivation | Q34608729 | ||
Human Cdc45 is a proliferation-associated antigen. | Q34645501 | ||
The role of pre-replicative complex (pre-RC) components in oncogenesis | Q34661644 | ||
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior | Q34714143 | ||
DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor | Q35165910 | ||
DNA replication origin interference increases the spacing between initiation events in human cells | Q35191023 | ||
Dynamics of pre-replication complex proteins during the cell division cycle | Q35213825 | ||
A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker. | Q35220061 | ||
An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene | Q35642112 | ||
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. | Q36752433 | ||
Cell cycle regulation of DNA replication. | Q36881426 | ||
Differential DNA replication origin activities in human normal skin fibroblast and HeLa cell lines | Q36889231 | ||
Analysis of re-replication from deregulated origin licensing by DNA fiber spreading | Q37041809 | ||
The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication | Q37169802 | ||
DNA replication and the GINS complex: localization on extended chromatin fibers | Q37202985 | ||
DNA replication in early S phase pauses near newly activated origins | Q37233544 | ||
Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival | Q37327314 | ||
Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches. | Q37630984 | ||
A human DNA replication origin: localization and transcriptional characterization | Q38331620 | ||
14-3-3sigma is a cruciform DNA binding protein and associates in vivo with origins of DNA replication | Q38362716 | ||
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro | Q38782589 | ||
In vivo association of Ku with mammalian origins of DNA replication | Q39265275 | ||
Eukaryotic chromosome replication | Q39364965 | ||
Ku86 is important for TrkA overexpression-induced breast cancer cell invasion | Q39623103 | ||
Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer | Q39649520 | ||
Quantitative protein expression profiling of 14-3-3 isoforms in human renal carcinoma shows 14-3-3 epsilon is involved in limitedly increasing renal cell proliferation | Q39767003 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1333-1347 | |
P577 | publication date | 2012-04-01 | |
P1433 | published in | Journal of Cellular Biochemistry | Q6294917 |
P1476 | title | Comparative analysis of pre-replication complex proteins in transformed and normal cells | |
P478 | volume | 113 |
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Q34227699 | Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish |
Q42175135 | Differential chromatin structure encompassing replication origins in transformed and normal cells |
Q37232780 | Diminished origin-licensing capacity specifically sensitizes tumor cells to replication stress. |
Q39278878 | Estrogen-induced upregulation and 3'-UTR shortening of CDC6 |
Q58782636 | Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes |
Q36916054 | Ku protein levels, localization and association to replication origins in different stages of breast tumor progression. |
Q38015243 | Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy |
Q31117926 | Monoallelic chromatin conformation flanking long-range silenced domains in cancer-derived and normal cells |
Q43444340 | Norcantharidin inhibits pre-replicative complexes assembly of HepG2 cells |
Q38734255 | Overexpression of minichromosome maintenance protein 10 in medulloblastoma and its clinical implications. |
Q33112680 | Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. |
Q52322877 | The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy. |
Q41950020 | The prognostic significance of Cdc6 and Cdt1 in breast cancer |
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