Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

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Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.0711339
P698PubMed publication ID22124136
P5875ResearchGate publication ID51833194

P50authorGabriel RabinovichQ17987510
Mercedes FuertesQ37841931
Norberto ZwirnerQ42880727
Raúl German SpallanzaniQ49191851
Carolina I DomaicaQ56166792
Diego O CrociQ130239211
P2093author name stringLucas E Rossi
Andrea Ziblat
Lara Lapyckyj
Damián E Avila
P2860cites workHistone acetyltransferasesQ29547823
Functions of natural killer cellsQ29614300
NK cell recognitionQ29615107
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancerQ29615649
Anticancer activities of histone deacetylase inhibitorsQ29616624
Up on the tightrope: natural killer cell activation and inhibitionQ29619175
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitorsQ33697130
Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general populationQ33928216
Polycystic ovarian syndrome in women with epilepsy: a reviewQ34345051
Histone deacetylase inhibitors in cancer therapyQ34659283
Reduced natural killer (NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptorsQ35828771
NKG2D function protects the host from tumor initiationQ36402828
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancyQ36484325
Surface NK receptors and their ligands on tumor cellsQ36490899
Antiepileptic drugs in non-epilepsy disorders: relations between mechanisms of action and clinical efficacyQ37029357
Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effectQ37095317
Drug Insight: histone deacetylase inhibitor-based therapies for cutaneous T-cell lymphomasQ37288403
Histone deacetylase inhibitors: a new perspective for the treatment of leukemiaQ37599067
Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organsQ37692292
Cytokine regulation of natural killer cell effector functionsQ37771915
Tumor immunoediting by NKp46.Q39713057
Histone deacetylase inhibitors prevent activation of tumour-reactive NK cells and T cells but do not interfere with their cytolytic effector functionsQ39722163
Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cellsQ39948537
Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity.Q40000380
NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificitiesQ40053992
Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12.Q40084538
Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cellsQ40108262
Histone deacetylase inhibitors suppress natural killer cell cytolytic activityQ40161252
Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulationQ40278633
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B.Q40344948
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activityQ40778493
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.Q43143715
Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesisQ44897188
Translocation-positive acute myeloid leukemia associated with valproic acid therapyQ44926636
HDAC6 expression is correlated with better survival in breast cancer.Q45122014
Cancer risk in long-term users of valproate: a population-based case-control study.Q45977880
HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer.Q46017171
Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproateQ46158181
Acute leukemia associated with valproic acid treatment: a novel mechanism for leukemogenesis?Q46408704
HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alphaQ46541460
Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproateQ46604673
Deacetylase inhibition promotes the generation and function of regulatory T cells.Q46961808
Enhanced in vivo growth of lymphoma tumors in the absence of the NK-activating receptor NKp46/NCR1.Q51833288
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function.Q52005889
Autocrine role of endogenous interleukin-18 on inflammatory cytokine generation by human neutrophils.Q53455289
P433issue2
P304page(s)321-331
P577publication date2011-11-28
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleHistone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
P478volume91

Reverse relations

cites work (P2860)
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