The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells.

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The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10585-011-9434-4
P698PubMed publication ID22080401
P5875ResearchGate publication ID51795927

P50authorMarc MesnilQ44502229
Leonard J FosterQ57127660
Norah DefamieQ57712872
Francoise DebiaisQ58380349
P2093author name stringVincent C Chen
Christian C Naus
Laurent Cronier
Pierre-Olivier Strale
Sophie Crespin
François-Xavier Bernard
Nathalie Pedretti
Jonathan Clarhaut
Coralie Lamiche
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Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP.Q34371624
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Gap junctions and cancer: new functions for an old storyQ37286213
Connexin43 increases the sensitivity of prostate cancer cells to TNFalpha-induced apoptosisQ37368462
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Junctional intercellular communication and the control of growthQ37884714
Alterations in Cx43 and OB-cadherin affect breast cancer cell metastatic potentialQ38294562
Effect of endothelin-1 on osteoblastic differentiation is modified by the level of connexin43: comparative study on calvarial osteoblastic cells isolated from Cx43+/- and Cx43+/+ mice.Q38346103
Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblastsQ39612205
The carboxy-terminal tail of connexin43 gap junction protein is sufficient to mediate cytoskeleton changes in human glioma cells.Q39698412
Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor.Q39780341
Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells.Q39908832
Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.Q40079512
Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminusQ40083691
Combination of non-viral connexin 43 gene therapy and docetaxel inhibits the growth of human prostate cancer in mice.Q40201258
Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cellsQ40222356
Changes in gap junctional connexin isoforms during prostate cancer progressionQ40382761
Contact stimulation of prostate cancer cell migration: the role of gap junctional coupling and migration stimulated by heterotypic cell-to-cell contacts in determination of the metastatic phenotype of Dunning rat prostate cancer cellsQ40419518
Breast cancer metastatic potential: correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cellsQ40536020
Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its mitigation by alpha-cateninQ40707383
Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communicationQ40816032
Differential effect of subcellular localization of communication impairing gap junction protein connexin43 on tumor cell growth in vivoQ40896682
Suppression of human prostate cancer cell growth by forced expression of connexin genesQ40966747
The gap junction communication channelQ40974984
A pre-loading method of evaluating gap junctional communication by fluorescent dye transferQ41364524
Communication between malignant glioma cells and vascular endothelial cells through gap junctionsQ44400718
Increased susceptibility to urethane-induced lung tumors in mice with decreased expression of connexin43.Q44912807
Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancerQ44918129
Triplex protein quantification based on stable isotope labeling by peptide dimethylation applied to cell and tissue lysatesQ46319535
Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells.Q48591901
Implications and challenges of connexin connections to cancer.Q55052930
Mutations in the second extracellular region of connexin 43 prevent localization to the plasma membrane, but do not affect its ability to suppress cell growth.Q55472714
Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human diseaseQ60585237
Gap junctional communication during human trophoblast differentiation: influence of human chorionic gonadotropinQ72019808
The effect of 1,25(OH)2D3 on alkaline phosphatase in osteoblastic osteosarcoma cellsQ72032912
Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: significant correlation with poor prognosisQ81729771
P433issue2
P921main subjectprostate cancerQ181257
P304page(s)111-122
P577publication date2011-11-12
P1433published inClinical & Experimental MetastasisQ13470030
P1476titleThe gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells
P478volume29

Reverse relations

cites work (P2860)
Q36134845All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction
Q41923292Alteration of osteoblast arrangement via direct attack by cancer cells: New insights into bone metastasis
Q31036068Connexin 43 (Cx43) Expression in Laryngeal Squamous Cell Carcinomas: Preliminary Data on Its Possible Prognostic Role
Q35793880Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration
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Q47770967Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications
Q26861688Connexins, gap junctions and tissue invasion
Q90193234Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer
Q61448933Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application
Q39026460Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer
Q26851127Gap junction and hemichannel-independent actions of connexins on cell and tissue functions--an update
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Q54540610Genetics: Transcribing for the enemy.
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Q93168864TGF-β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling
Q37986402The role of connexins in prostate cancer promotion and progression
Q51600585Upregulation of connexin43 contributes to PX-12-induced oxidative cell death.

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