Comparison of N- and P/Q-type voltage-gated calcium channel current inhibition.

scientific article published in June 1997

Comparison of N- and P/Q-type voltage-gated calcium channel current inhibition. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.17-12-04570.1997
P932PMC publication ID6573354
P698PubMed publication ID9169518

P50authorKevin P. M. CurrieQ67543357
P2093author name stringA P Fox
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channelQ24336849
Direct binding of G-protein betagamma complex to voltage-dependent calcium channelsQ28302204
Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poisonQ29029753
Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+Q34019162
Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunitsQ34380635
Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscleQ34633282
G protein-coupled mechanisms and nervous signalingQ35262001
Localization and functional properties of a rat brain alpha 1A calcium channel reflect similarities to neuronal Q- and P-type channelsQ35863195
Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channelQ37042524
Determinants of the G protein-dependent opioid modulation of neuronal calcium channelsQ37718351
Inhibition of the interaction of G protein G(o) with calcium channels by the calcium channel beta‐subunit in rat neuronesQ38294762
Identification of three subunits of the high affinity omega-conotoxin MVIIC-sensitive Ca2+ channelQ38356792
Bursts of action potential waveforms relieve G-protein inhibition of recombinant P/Q-type Ca2+ channels in HEK 293 cellsQ39457098
Voltage- and time-dependent inhibition of neuronal calcium channels by a GTP-binding protein in a mammalian cell lineQ39503567
Roles of N-type and Q-type Ca2+ channels in supporting hippocampal synaptic transmissionQ39757650
Modulation of ion-channel function by G-protein-coupled receptorsQ40397855
The G.L. Brown Prize Lecture. Voltage-dependent calcium channels and their modulation by neurotransmitters and G proteinsQ40515661
Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons.Q40714401
Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit.Q41132629
Modulation of Ca2+ channels by G-protein beta gamma subunitsQ41214714
Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependenceQ41276531
Effects of N-, P- and Q-type neuronal calcium channel antagonists on mammalian peripheral neurotransmissionQ41872410
Facilitation of N-type calcium current is dependent on the frequency of action potential-like depolarizations in dissociated cholinergic basal forebrain neurons of the guinea pig.Q42529108
Sodium and calcium channels in bovine chromaffin cellsQ42665483
Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neuronsQ44706223
A study of the mechanism of Ca2+ current inhibition produced by serotonin in rat dorsal raphe neuronsQ44891251
Multiple structural elements in voltage-dependent Ca2+ channels support their inhibition by G proteinsQ46449835
Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neuronsQ46560276
Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapsesQ48162032
GABAB receptor inhibition of P-type Ca2+ channels in central neuronsQ48293724
P-type calcium channels in rat central and peripheral neuronsQ48465981
Abolition of G protein inhibition of α1A and α1B calcium channels by co‐expression of the β3 subunitQ49042605
Isoproterenol potentiates synaptic transmission primarily by enhancing presynaptic calcium influx via P- and/or Q-type calcium channels in the rat amygdala.Q49159194
ATP serves as a negative feedback inhibitor of voltage-gated Ca2+ channel currents in cultured bovine adrenal chromaffin cells.Q50749845
Kinetic basis for the voltage-dependent inhibition of N-type calcium current by somatostatin and norepinephrine in chick sympathetic neurons.Q51658096
Modulation of N-type calcium channels in bullfrog sympathetic neurons by luteinizing hormone-releasing hormone: kinetics and voltage dependenceQ54052748
Different types of calcium channels mediate central synaptic transmissionQ59054415
Activation of facilitation calcium channels in chromaffin cells by D1 dopamine receptors through a cAMP/protein kinase A-dependent mechanismQ59065349
Voltage-dependent phosphorylation may recruit Ca2+ current facilitation in chromaff in cellsQ60063419
Inhibition of N- and P-type calcium currents and the after-hyperpolarization in rat motoneurones by serotoninQ63977697
ω-Conotoxin GVIA blocks a Ca2+ current in bovine chromaffin cells that is not of the “classic” N typeQ67485618
Two types of Ca2+ currents are found in bovine chromaffin cells: facilitation is due to the recruitment of one typeQ67699259
LHRH and GTP-gamma-S modify calcium current activation in bullfrog sympathetic neuronsQ68467691
Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neuronsQ69364773
Multiple subtypes of voltage-gated calcium channel mediate transmitter release from parasympathetic neurons in the mouse bladderQ71388106
Transmitter-mediated inhibition of N-type calcium channels in sensory neurons involves multiple GTP-binding proteins and subunitsQ72421536
Multiple calcium channel types control glutamatergic synaptic transmission in the hippocampusQ72658211
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectvoltageQ25428
P304page(s)4570-4579
P577publication date1997-06-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleComparison of N- and P/Q-type voltage-gated calcium channel current inhibition
P478volume17

Reverse relations

cites work (P2860)
Q42252461Activity-dependent neurotrophin signaling underlies developmental switch of Ca2+ channel subtypes mediating neurotransmitter release
Q39750895Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
Q35296539Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits
Q73665670Allosteric modulation of [(3)H]gabapentin binding by ruthenium red
Q35294357Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells.
Q34657791Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture
Q81152568Changes in synaptic transmission properties due to the expression of N-type calcium channels at the calyx of Held synapse of mice lacking P/Q-type calcium channels
Q36412421Custom distinctions in the interaction of G-protein beta subunits with N-type (CaV2.2) versus P/Q-type (CaV2.1) calcium channels
Q36017274Decay of prepulse facilitation of N type calcium channels during G protein inhibition is consistent with binding of a single Gbeta subunit
Q48108808Decreased G-protein-mediated regulation and shift in calcium channel types with age in hippocampal cultures.
Q37347568Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses
Q37677444Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation
Q39409730Differential facilitation of N- and P/Q-type calcium channels during trains of action potential-like waveforms.
Q47977208Differential inhibition of N and P/Q Ca2+ currents by 5-HT1A and 5-HT1D receptors in spinal neurons of Xenopus larvae
Q28582330Differential modulation of N-type 1B and P/Q-type 1A calcium channels by different G protein subunit isoforms
Q36412143Differential occurrence of reluctant openings in G-protein-inhibited N- and P/Q-type calcium channels
Q40134313Differential regulation of endogenous N- and P/Q-type Ca2+ channel inactivation by Ca2+/calmodulin impacts on their ability to support exocytosis in chromaffin cells
Q33708220Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics
Q24556684Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca2+ channel activity and inhibitory synaptic transmission
Q44300144Enhanced G protein-dependent modulation of excitatory synaptic transmission in the cerebellum of the Ca2+ channel-mutant mouse, tottering.
Q41034726Facilitation of rabbit alpha1B calcium channels: involvement of endogenous Gbetagamma subunits
Q28589053Functional compensation of P/Q by N-type channels blocks short-term plasticity at the calyx of Held presynaptic terminal
Q34639816G protein modulation of CaV2 voltage-gated calcium channels
Q41028797G-Protein-dependent facilitation of neuronal alpha1A, alpha1B, and alpha1E Ca channels.
Q40830570G-protein inhibition of N- and P/Q-type calcium channels: distinctive elementary mechanisms and their functional impact.
Q77911316G-proteins are involved in 5-HT receptor-mediated modulation of N- and P/Q- but not T-type Ca2+ channels
Q35925069Gabapentin inhibits catecholamine release from adrenal chromaffin cells
Q47949538Identification of the amino terminus of neuronal Ca2+ channel alpha1 subunits alpha1B and alpha1E as an essential determinant of G-protein modulation.
Q34529958Inhibition of Ca2+ channels and adrenal catecholamine release by G protein coupled receptors.
Q44007040Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells
Q46553746Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel.
Q43850730Kappa Opioid Receptor Activation in the Nucleus Accumbens Inhibits Glutamate and GABA Release Through Different Mechanisms
Q50510433Kinetic and pharmacological properties of Ca(2+) currents in postganglionic sympathetic neurones projecting to muscular and cutaneous effectors.
Q24657724Loose coupling between calcium channels and sites of exocytosis in chromaffin cells
Q42450389Low Frequency Stimulation of Mouse Adrenal Slices Reveals a Clathrin‐Independent, Protein Kinase C‐Mediated Endocytic Mechanism
Q34458100Mechanisms of modulation of voltage-dependent calcium channels by G proteins
Q35779417Membrane-localized β-subunits alter the PIP2 regulation of high-voltage activated Ca2+ channels
Q48450854Modulation of Ca2+ channel currents of acutely dissociated rat periaqueductal grey neurons
Q35000594Modulation of synaptic transmission by oxytocin and vasopressin in the supraoptic nucleus.
Q47754115Modulation of voltage-dependent calcium channels by G proteins
Q35682291Neurotransmitter modulation of neuronal calcium channels.
Q46776177New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels
Q28363334Oxytocin retrogradely inhibits evoked, but not miniature, EPSCs in the rat supraoptic nucleus: role of N- and P/Q-type calcium channels
Q34165852P/Q and N Channels Control Baseline and Spike-Triggered Calcium Levels in Neocortical Axons and Synaptic Boutons
Q73348002P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels
Q33812271Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer
Q26774991Pedunculopontine Gamma Band Activity and Development
Q81175649Pharmacological and biophysical properties of Ca2+ channels and subtype distributions in human adrenal chromaffin cells
Q35605115Pituitary adenylate cyclase-activating peptide (PACAP) recruits low voltage-activated T-type calcium influx under acute sympathetic stimulation in mouse adrenal chromaffin cells
Q42946209Postsynaptic Cell Type–Dependent Cholinergic Regulation of GABAergic Synaptic Transmission in Rat Insular Cortex
Q28568674Presynaptic Cav2.1 and Cav2.2 differentially influence release dynamics at hippocampal excitatory synapses
Q46612900Presynaptic N-type and P/Q-type Ca2+ channels mediating synaptic transmission at the calyx of Held of mice.
Q39750122Presynaptic specificity of endocannabinoid signaling in the hippocampus
Q36253524Quantification of reserve pool dopamine in methionine sulfoxide reductase A null mice
Q36565441Regulation of Ca(V)2 calcium channels by G protein coupled receptors.
Q54102371Regulation of Ca2+ influx by a protein kinase C activator in chromaffin cells: differential role of P/Q- and L-type Ca2+ channels.
Q35048992SO-3, a new O-superfamily conopeptide derived from Conus striatus, selectively inhibits N-type calcium currents in cultured hippocampal neurons
Q50520515Stellate neurones innervating the rat heart express N, L and P/Q calcium channels.
Q43694133Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons
Q36329427Targeted disruption of the Ca2+ channel beta3 subunit reduces N- and L-type Ca2+ channel activity and alters the voltage-dependent activation of P/Q-type Ca2+ channels in neurons.
Q39450985The Ca2+ channel beta3 subunit differentially modulates G-protein sensitivity of alpha1A and alpha1B Ca2+ channels.
Q24657270The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells
Q37001355The role of MAP1A light chain 2 in synaptic surface retention of Cav2.2 channels in hippocampal neurons
Q48405968Voltage-dependent Ca2+ currents in rat cardiac dorsal root ganglion neurons.
Q45805613ω-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential

Search more.