Selection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure.

scientific article published on August 2000

Selection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.44.8.2182-2184.2000
P932PMC publication ID90035
P698PubMed publication ID10898697

P50authorJesus BlazquezQ68273789
P2093author name stringF Baquero
M I Morosini
M C Negri
P2860cites workIdentification of amino acid substitutions that alter the substrate specificity of TEM-1 beta-lactamaseQ39935716
Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibioticsQ41311524
A standard numbering scheme for the class A beta-lactamasesQ42861944
Evolution of antibiotic resistance: several different amino acid substitutions in an active site loop alter the substrate profile of beta-lactamase.Q54636575
DNA sequencing with chain-terminating inhibitorsQ22066207
A functional classification scheme for beta-lactamases and its correlation with molecular structureQ24677460
A237T as a modulating mutation in naturally occurring extended-spectrum TEM-type beta-lactamasesQ33695143
An efficient method for generating proteins with altered enzymatic properties: application to beta-lactamaseQ34321482
Single amino acid replacements at positions altered in naturally occurring extended-spectrum TEM beta-lactamases.Q35111013
Implication of Ile-69 and Thr-182 residues in kinetic characteristics of IRT-3 (TEM-32) beta-lactamaseQ35128617
Systematic mutagenesis of the active site omega loop of TEM-1 beta-lactamaseQ35604377
Characterization of a new TEM-type beta-lactamase resistant to clavulanate, sulbactam, and tazobactam in a clinical isolate of Escherichia coli.Q35897209
A natural polymorphism in beta-lactamase is a global suppressorQ36560876
Characterization of TEM-1 beta-lactamase mutants from positions 238 to 241 with increased catalytic efficiency for ceftazidime.Q36740539
Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity for aztreonam and ceftazidimeQ36818729
An additional ionic bond suggested by molecular modelling of TEM-2 might induce a slight discrepancy between catalytic properties of TEM-1 and TEM-2 beta-lactamasesQ38393699
Classification of beta-lactamases: groups 1, 2a, 2b, and 2b'.Q38640013
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)2182-2184
P577publication date2000-08-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleSelection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure
P478volume44

Reverse relations

cites work (P2860)
Q53896773A preliminary study on extended-spectrum beta-lactamase producing Klebsiella species from a South Indian hospital.
Q36595848Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world
Q86832377Bypass of genetic constraints during mutator evolution to antibiotic resistance
Q33980535Concentration-dependent selection of small phenotypic differences in TEM beta-lactamase-mediated antibiotic resistance
Q54372713Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials.
Q42577782Effect of subinhibitory concentrations of antibiotics on intrachromosomal homologous recombination in Escherichia coli
Q37896674Emergence and spread of antibiotic resistance following exposure to antibiotics
Q27639212Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs
Q28472615Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance
Q49831017Evolving Bacterial Fitness with an Expanded Genetic Code.
Q34617402Experimental Prediction of the Natural Evolution of Antibiotic Resistance
Q37420296Extended Spectrum beta-Lactamases among Gram-Negative Bacterial Isolates from Clinical Specimens in Three Major Hospitals in Northern Jordan
Q54536455Extended spectrum beta-lactamases of Escherichia coli and Klebsiella pneumoniae in a South Indian tertiary care hospital.
Q24550671Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat
Q34698874Genetic constraints on protein evolution
Q54753706How to measure and monitor antimicrobial consumption and resistance.
Q79162727Hypermutation as a Factor Contributing to the Acquisition of Antimicrobial Resistance
Q37735903Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance
Q28477196Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories
Q27023284Origin and proliferation of multiple-drug resistance in bacterial pathogens
Q36424079Overview of the epidemiological profile and laboratory detection of extended-spectrum beta-lactamases
Q37002813Predicting antibiotic resistance
Q34112966Predicting evolution by in vitro evolution requires determining evolutionary pathways
Q34614621Predicting evolutionary potential: in vitro evolution accurately reproduces natural evolution of the tem beta-lactamase
Q48331405Protected environments allow parallel evolution of a bacterial pathogen in a patient subjected to long-term antibiotic therapy
Q35236711Role of pleiotropy during adaptation of TEM-1 β-lactamase to two novel antibiotics
Q47150482Scientific Opinion on the public health risks of bacterial strains producing extended-spectrum β-lactamases and/or AmpC β-lactamases in food and food-producing animals
Q37406333Side effects of antibiotics on genetic variability.
Q33555173bla(SHV) Genes in Klebsiella pneumoniae: different allele distributions are associated with different promoters within individual isolates

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