A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

research work

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VACCINE.2014.03.020
P2888exact matchhttp://ugspace.ug.edu.gh/handle/123456789/25139
P8608Fatcat IDrelease_b5h7fe3dfzfbjapxuv4ahytghm
P698PubMed publication ID24662702
P5875ResearchGate publication ID261067844
P8602University of Ghana Digital Collections (UGSpace) ID25139

P50authorTeun BousemaQ44168464
Marga van de Vegte-BolmerQ45380602
Morten Hanefeld DziegielQ55100179
Susheel K. SinghQ55182102
Michael TheisenQ58310143
Robert SauerweinQ72530989
Will RoeffenQ72536015
P2093author name stringMichael Christiansen
Theo Arens
Theisen, M.
Sophie Jones
Bright Adu
Adu, B.
Singh, S.K.
Christiansen, M.
Dziegiel, M.H.
Bousema, T.
Jones, S.
Roeffen, W.
Sauerwein, R.
Amoah, L.
Andersen, G.
Arens, T.
Gorm Andersen
Linda Amoah
Régis Wendpayangde Tiendrebeogo
van de Vegte-Bolmer, M.
P2860cites workThe dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in TanzaniaQ28744581
Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killingQ30897109
A Plasmodium falciparum GLURP-MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodiesQ33198902
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccinesQ33368617
A potent malaria transmission blocking vaccine based on codon harmonized full length Pfs48/45 expressed in Escherichia coliQ33485233
The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infectionsQ33587496
A Research Agenda to Underpin Malaria EradicationQ33818020
Selection of glutamate-rich protein long synthetic peptides for vaccine development: antigenicity and relationship with clinical protection and immunogenicityQ34008755
Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and eliminationQ34177472
Immunogenicity of the Plasmodium falciparum glutamate-rich protein expressed by vaccinia virusQ34533068
Naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs48/45 and Pfs230 in an area of seasonal transmissionQ35598030
Association between protection against clinical malaria and antibodies to merozoite surface antigens in an area of hyperendemicity in Myanmar: complementarity between responses to merozoite surface protein 3 and the 220-kilodalton glutamate-rich proQ36227049
Sequential expression of antigens on sexual stages of Plasmodium falciparum accessible to transmission-blocking antibodies in the mosquitoQ36351262
Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in miceQ36670217
Surface antigens of Plasmodium falciparum gametocytes--a new class of transmission-blocking vaccine targets?Q37487002
Lactococcus lactis-based vaccines from laboratory bench to human use: an overviewQ37966471
Evidence of non-neutral polymorphism in Plasmodium falciparum gamete surface protein genes Pfs47 and Pfs48/45.Q38876779
Transmission-blocking effects of sera from malaria-exposed individuals on Plasmodium falciparum isolates from gametocyte carriersQ38977787
Uses of mosquito-stage transmission-blocking vaccines against Plasmodium falciparumQ39473663
Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, SenegalQ39515540
The glutamate-rich protein (GLURP) of Plasmodium falciparum is a target for antibody-dependent monocyte-mediated inhibition of parasite growth in vitroQ39569469
Measurement by membrane feeding of reduction in Plasmodium falciparum transmission induced by endemic seraQ40959724
Plasmodium falciparum: heterologous synthesis of the transmission-blocking vaccine candidate Pfs48/45 in recombinant vaccinia virus-infected cellsQ41003251
Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoesQ41946006
Studies on antigenic competitionQ42101792
Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibitionQ42275109
Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding AssayQ43571629
Heterologous expression of the C-terminal antigenic domain of the malaria vaccine candidate Pfs48/45 in the green algae Chlamydomonas reinhardtiiQ43645737
A longitudinal study of immune responses to Plasmodium falciparum sexual stage antigens in Tanzanian adultsQ43945792
Transmission blocking malaria vaccinesQ44145217
Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static culturesQ44166470
A comparison of transmission-blocking activity with reactivity in a Plasmodium falciparum 48/45-kD molecule-specific competition enzyme-linked immunosorbent assay.Q44169960
The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areasQ44238175
Naturally acquired antibodies to the glutamate-rich protein are associated with protection against plasmodium falciparum malariaQ46163143
Conservation and heterogeneity of the glutamate-rich protein (GLURP) among field isolates and laboratory lines of Plasmodium falciparumQ47812641
Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies.Q47829675
Immunological properties of recombinant proteins of the transmission blocking vaccine candidate, Pfs48/45, of the human malaria parasite Plasmodium falciparum produced in Escherichia coli.Q47837358
Assembly and expression of a synthetic gene encoding the antigen Pfs48/45 of the human malaria parasite Plasmodium falciparum in yeastQ47857505
Production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expressing bacterial PNGase F.Q48007592
Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trialQ48034345
Cloning and expression of the gene coding for the transmission blocking target antigen Pfs48/45 of Plasmodium falciparumQ48103837
Plasmodium falciparum: production and characterization of rat monoclonal antibodies specific for the sexual-stage Pfs48/45 antigenQ73509627
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectvaccineQ134808
malaria vaccineQ6741353
P48/45Q18971545
malaria transmissionQ56928847
P304page(s)2623-2630
P577publication date2014-01-01
2014-03-21
P1433published inElsevier BVQ746413
VaccineQ7907941
P1476titleA multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages
P478volume32