MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.

scientific article published on 7 June 2011

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011NatCo...2..338K
P356DOI10.1038/NCOMMS1345
P698PubMed publication ID21654638

P50authorKazuhiko KoikeQ21699620
Motoyuki OtsukaQ61157106
P2093author name stringMasao Omata
Naoya Kato
Weiping J Zhang
Haruhiko Yoshida
Yuji Kondo
Takeshi Yoshikawa
Charles Vadnais
Akemi Takata
Takahiro Kishikawa
Masao Akanuma
Zhifang Xie
Alain Nepveu
Kentaro Kojima
Young Jun Kang
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The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasionQ42176518
p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expressionQ42660335
CUTL1 is phosphorylated by protein kinase A, modulating its effects on cell proliferation and motilityQ42803832
Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosisQ44358725
Clinical classification of hepatoma in Japan according to serial changes in serum alpha-fetoprotein levelsQ45025831
Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic typesQ45381635
High alpha-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and beta-catenin mutations.Q45601546
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Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomasQ82297408
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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
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miR-122 regulation of lipid metabolism revealed by in vivo antisense targetingQ29547487
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Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failureQ30498092
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Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development.Q34138074
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The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phaseQ34519903
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MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.Q34786558
MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinomaQ34964774
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic propertiesQ34993023
Hepatomegaly in transgenic mice expressing the homeobox gene Cux-1Q35636935
Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasiaQ35679923
Issues in screening and surveillance for hepatocellular carcinomaQ35929133
Relationship between serum alpha-foetoprotein, cirrhosis and survival in hepatocellular carcinomaQ36045666
Survival rate in patients with hepatocellular carcinoma: a retrospective analysis of 389 patientsQ36615885
The multiple roles of CUX1: insights from mouse models and cell-based assaysQ37099815
The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiationQ37286651
Molecular therapy for the treatment of hepatocellular carcinomaQ37329048
Clinical features and prognosis of hepatocellular carcinoma with reference to serum alpha-fetoprotein levels. Analysis of 606 patientsQ38207543
CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasivenessQ38325113
Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expressionQ39788628
p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludinQ39820143
Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genesQ40051898
CUTL1 promotes tumor cell migration by decreasing proteasome-mediated Src degradation.Q40157234
A versatile tool for conditional gene expression and knockdownQ40325913
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.Q41831270
P2507corrigendum / erratumErratum: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinomaQ61207060
P407language of work or nameEnglishQ1860
P304page(s)338
P577publication date2011-06-07
P1433published inNature CommunicationsQ573880
P1476titleMicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma
P478volume2

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Q61207060Erratum: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinomamain subjectP921

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