| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/MINF.201300107 |
| P8608 | Fatcat ID | release_pcyux36ppvgidp5alapdgc7ili |
| P698 | PubMed publication ID | 27480234 |
| P50 | author | Aixia Yan | Q37839172 |
| Johannes Kirchmair | Q51782466 | ||
| P2093 | author name string | Lu Tan | |
| Maolin Wang | |||
| Shouyi Xuan | |||
| Hang Kang | |||
| P2860 | cites work | Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design | Q27620348 |
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| The Generation of a Unique Machine Description for Chemical Structures-A Technique Developed at Chemical Abstracts Service | Q28837925 | ||
| Comparison of the predicted and observed secondary structure of T4 phage lysozyme | Q29398301 | ||
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| N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase | Q34779869 | ||
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| The use of receiver operating characteristic curves in biomedical informatics | Q36274414 | ||
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| Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action | Q37014638 | ||
| Prediction of human intestinal absorption by GA feature selection and support vector machine regression | Q37083213 | ||
| Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors | Q37399117 | ||
| Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase | Q38299500 | ||
| Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site | Q38334448 | ||
| Curcumin Analogs with Altered Potencies against HIV-1 Integrase as Probes for Biochemical Mechanisms of Drug Action | Q38342984 | ||
| HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching | Q38347789 | ||
| Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy | Q38425605 | ||
| Prediction of aqueous solubility of organic compounds based on a 3D structure representation | Q38452717 | ||
| Discovery of HIV-1 integrase inhibitors by pharmacophore searching. | Q38558849 | ||
| Design, Synthesis, and Biological Evaluation of Novel Hybrid Dicaffeoyltartaric/Diketo Acid and Tetrazole-Substitutedl-Chicoric Acid Analogue Inhibitors of Human Immunodeficiency Virus Type 1 Integrase | Q39639744 | ||
| New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase--discovery of a new polyhydroxylated antiviral agent | Q39694118 | ||
| Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors | Q39913483 | ||
| 2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-one-based HIV-1 integrase inhibitors | Q40032687 | ||
| Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives | Q40065034 | ||
| Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones. | Q40067524 | ||
| Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase | Q40342534 | ||
| Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors | Q40357821 | ||
| Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines | Q40547646 | ||
| Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase | Q40561625 | ||
| 2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays | Q40603490 | ||
| Azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors | Q40663130 | ||
| Metal-dependent inhibition of HIV-1 integrase | Q40684087 | ||
| Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors. | Q40719557 | ||
| Synthesis and hiv-1 integrase inhibitory activities of catechol and bis-Catechol derivatives | Q40766742 | ||
| Styrylquinoline Derivatives: A New Class of Potent HIV-1 Integrase Inhibitors That Block HIV-1 Replication in CEM Cells | Q41024638 | ||
| Hydroxylated aromatic inhibitors of HIV-1 integrase | Q41283270 | ||
| Design, synthesis, and anti-integrase activity of catechol-DKA hybrids | Q42166288 | ||
| Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling. | Q42539086 | ||
| Arylamide inhibitors of HIV-1 integrase | Q42550097 | ||
| Hydrazide-containing inhibitors of HIV-1 integrase. | Q42550706 | ||
| Coumarin-based inhibitors of HIV integrase | Q42551512 | ||
| Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease. | Q42555560 | ||
| Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: Azoles: Effective metal chelators | Q42930789 | ||
| Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor | Q42937331 | ||
| Design, synthesis and structure-activity studies of rhodanine derivatives as HIV-1 integrase inhibitors. | Q42958802 | ||
| Substituted 2-pyrrolinone inhibitors of HIV-1 integrase | Q43418943 | ||
| Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: New structural insight into the HIV-1 integrase inhibition | Q43558453 | ||
| Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors | Q43600660 | ||
| CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site | Q43768382 | ||
| Prediction of bioactivity of HIV-1 integrase ST inhibitors by multilinear regression analysis and support vector machine | Q44528756 | ||
| From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes. | Q44619681 | ||
| Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors | Q44672373 | ||
| Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors | Q44718814 | ||
| 6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays | Q44802594 | ||
| Synthesis of novel thiazolothiazepine based HIV-1 integrase inhibitors. | Q44986910 | ||
| Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides | Q45040342 | ||
| Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors | Q45084485 | ||
| Dynamic receptor-based pharmacophore model development and its application in designing novel HIV-1 integrase inhibitors | Q45294408 | ||
| Discovery and structure-activity relationship studies of a unique class of HIV-1 integrase inhibitors. | Q46010734 | ||
| Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity | Q46109839 | ||
| How similar are similarity searching methods? A principal component analysis of molecular descriptor space | Q46174895 | ||
| Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection | Q46396658 | ||
| Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation | Q46470915 | ||
| Synthesis and HIV-1 integrase inhibition of novel bis- or tetra-coumarin analogues | Q46867548 | ||
| Beta-diketo acids with purine nucleobase scaffolds: novel, selective inhibitors of the strand transfer step of HIV integrase | Q46913365 | ||
| Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors. | Q46969999 | ||
| Classification of Active and Weakly Active ST Inhibitors of HIV-1 Integrase Using a Support Vector Machine | Q47288588 | ||
| Bounds on error expectation for support vector machines | Q52074441 | ||
| Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-ones | Q53590784 | ||
| Self-Organized Formation of Topologically Correct Feature Maps | Q56112936 | ||
| Deriving the 3D structure of organic molecules from their infrared spectra | Q60176819 | ||
| Three-dimensional quantitative structure-activity relationship (QSAR) of HIV integrase inhibitors: a comparative molecular field analysis (CoMFA) study | Q72117401 | ||
| Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors | Q79421775 | ||
| HIV-1 integrase inhibition of biscoumarin analogues | Q83229505 | ||
| P433 | issue | 9-10 | |
| P921 | main subject | support vector machine | Q282453 |
| P304 | page(s) | 811-826 | |
| P577 | publication date | 2013-09-09 | |
| P1433 | published in | Molecular Informatics | Q3319476 |
| P1476 | title | Support Vector Machine (SVM) Models for Predicting Inhibitors of the 3' Processing Step of HIV-1 Integrase | |
| P478 | volume | 32 |
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