Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia.

scientific article published on 11 May 2011

Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CNCR.26192
P698PubMed publication ID21563174
P5875ResearchGate publication ID51118061

P50authorKebin LiuQ47818314
P2093author name stringRui Wang
Muthusamy Thangaraju
Zheng Dong
Troy A Baudino
In-Kiu Kwon
Darren D Browning
Nikhil Prakash
Renee Bozard
P2860cites workPIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxiaQ24293208
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasisQ24608039
Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxiaQ28283184
Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrityQ28509565
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesisQ29614537
Tumorigenesis and the angiogenic switchQ29619849
Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targetingQ33716178
Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP actionQ33732652
Cross-talk between enteric pathogens and the intestineQ34156247
Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.Q34339343
Exisulind, a selective apoptotic antineoplastic drugQ34481793
Cancer's molecular sweet tooth and the Warburg effect.Q34566915
Biomarkers of response and resistance to antiangiogenic therapyQ34673567
Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesisQ34747795
Bacterial enterotoxins are associated with resistance to colon cancer.Q34808083
Diarrhea or colorectal cancer: can bacterial toxins serve as a treatment for colon cancer?Q34865462
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Hypoxia: a key regulator of angiogenesis in cancerQ36866153
Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancerQ37082792
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisitedQ37403323
Targeting the hypoxia-inducible factor (HIF) pathway in cancer.Q37587446
cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatmentQ37855854
PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.Q39721627
The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.Q39802240
Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesisQ40330909
An anti-tumor role for cGMP-dependent protein kinaseQ40356929
A role for cyclic-GMP dependent protein kinase in anoikisQ40378506
Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cellsQ40550132
Functional analysis of type 1alpha cGMP-dependent protein kinase using green fluorescent fusion proteinsQ40817121
Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.Q42941313
Fractal and image analysis of the microvasculature in normal intestinal submucosa and intestinal polyps in Apc(Min/+) miceQ44081282
Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cellsQ45139102
Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.Q46507418
Antiangiogenic therapy: a universal chemosensitization strategy for cancer?Q83854395
Why do tumors become resistant to antiangiogenesis drugs?Q84826712
P433issue23
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
colon cancerQ18555025
P304page(s)5282-5293
P577publication date2011-05-11
P1433published inCancerQ326041
P1476titleCyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia
P478volume117

Reverse relations

cites work (P2860)
Q38123175COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs
Q39353975Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa