| P2093 | author name string | C H Sibley | |
| | C V Plowe | |
| | W M Watkins | |
| | P A Winstanley | |
| | E K Mberu | |
| | A Nzila-Mounda | |
| P2860 | cites work | Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria | Q27861937 |
| | Human malaria parasites in continuous culture | Q28131626 |
| | Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum | Q33680054 |
| | Potentiating effect of pyrimethamine and sulfadoxine against dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi | Q33739569 |
| | Spread of chloroquine resistance in Plasmodium falciparum | Q34355288 |
| | Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria. | Q34743292 |
| | Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum | Q35618862 |
| | Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR | Q35927120 |
| | Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase | Q35988728 |
| | Folate metabolism in malaria | Q36630805 |
| | A new in vitro test for pyrimethamine/sulfadoxine susceptibility of Plasmodium falciparum and its correlation with in vivo resistance in Kenya | Q36875739 |
| | The dynamics of drug resistance in Plasmodium falciparum | Q37298103 |
| | Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance | Q37739332 |
| | Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria | Q37739425 |
| | Child malaria treatment practices among mothers in Kenya | Q39110952 |
| | Community pyrimethamine-sulfadoxine use and prevalence of resistant Plasmodium falciparum genotypes in Mali: a model for deterring resistance | Q39436891 |
| | Resistance to pyrimethamine/sulfadoxine in Plasmodium falciparum in 12 villages in north east Tanzania and a test of chlorproguanil/dapsone | Q39533597 |
| | Poor efficacy of antimalarial biguanide-dapsone combinations in the treatment of acute, uncomplicated, falciparum malaria in Thailand | Q39592896 |
| | In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs | Q39779567 |
| | In vitro activities of and mechanisms of resistance to antifol antimalarial drugs | Q39849631 |
| | A randomised controlled trial to assess the relative efficacy of chloroquine, amodiaquine, halofantrine and Fansidar in the treatment of uncomplicated malaria in children. | Q40671669 |
| | Chloroquine treatment of falciparum malaria in an area of Kenya of intermediate chloroquine resistance | Q40790643 |
| | In vitro susceptibility of Plasmodium falciparum isolates from Jilore, Kenya, to antimalarial drugs | Q41913131 |
| | The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses | Q41913682 |
| | Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins | Q41927581 |
| | Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum | Q41928961 |
| | Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization | Q41928982 |
| | Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates | Q41931399 |
| | Pyrimethamine and Proguanil Resistance-Conferring Mutations in Plasmodium falciparum Dihydrofolate Reductase: Polymerase Chain Reaction Methods for Surveillance in Africa | Q41933010 |
| | Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. | Q41934737 |
| | Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa | Q41937986 |
| | Quinine treatment of severe falciparum malaria in African children: a randomized comparison of three regimens | Q41941225 |
| | Culture of human malaria parasites Plasmodium falciparum | Q43962160 |
| | Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life | Q44012338 |
| | Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range | Q46154949 |
| | Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea | Q46340740 |
| | Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance | Q46878245 |
| | Prevalence of the dihydrofolate reductase Asn-108 mutation as the basis for pyrimethamine-resistant falciparum malaria in the Brazilian Amazon. | Q47872182 |
| | A preliminary pharmacokinetic study of the antimalarial drugs, proguanil and chlorproguanil | Q47900426 |
| | Response of Plasmodium falciparum to dihydrofolate reductase inhibitors in Malindi, Kenya | Q47920637 |
| | Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum | Q48003670 |
| | Rapid detection of pyrimethamine susceptibility of Plasmodium falciparum by restriction endonuclease digestion of the dihydrofolate reductase gene | Q48026910 |
| | Plasmodium falciparum: mutation pattern in the dihydrofolate reductase-thymidylate synthase genes of Vietnamese isolates, a novel mutation, and coexistence of two clones in a Thai patient | Q48033279 |
| | Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum | Q48285515 |
| | Plasmodium falciparum: detection of antifolate resistance by mutation-specific restriction enzyme digestion. | Q54173614 |
| | Plasmodium falciparum: rapid detection of dihydrofolate reductase mutations that confer resistance to cycloguanil and pyrimethamine. | Q54269130 |
| | Characterization of polymerase chain reaction amplification of specific alleles | Q61820216 |
| | Antibacterial synergism: a proposal for chemotherapeutic potentiation between trimethoprim and sulfamethoxazole | Q67492092 |
| | PCR amplification of specific alleles (PASA) is a general method for rapidly detecting known single-base changes | Q67741544 |
| | Mismatch amplification mutation assay (MAMA): application to the c-H-ras gene | Q67997592 |
| | Amplification refractory mutation system for prenatal diagnosis and carrier assessment in cystic fibrosis | Q69377407 |
| | Mechanisms of sulfadoxine resistance in Plasmodium falciparum | Q69883752 |
| | Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid | Q69887088 |
| | Synergistic Antimalarial Activity of Pyrimethamine and Sulfadoxine against Plasmodium falciparum In Vitro * | Q70360226 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Kenya | Q114 |
| | Plasmodium falciparum | Q311383 |
| | pyrimethamine | Q421072 |
| P304 | page(s) | 164-169 | |
| P577 | publication date | 1998-01-01 | |
| P1433 | published in | Antimicrobial Agents and Chemotherapy | Q578004 |
| P1476 | title | Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain | |
| P478 | volume | 42 | |