AM3, a natural glycoconjugate, induces the functional maturation of human dendritic cells

scientific article published on 14 April 2008

AM3, a natural glycoconjugate, induces the functional maturation of human dendritic cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJP.2008.87
P932PMC publication ID2439514
P698PubMed publication ID18414382
P5875ResearchGate publication ID5439041

P2093author name stringP Roda-Navarro
S González
R Moreno-Otero
P L Majano
J P Pivel
A L Corbí
J L Alonso-Lebrero
M López-Cabrera
I Benedicto
P Sanz-Cameno
Y Rodríguez-Muñoz
L Aragoneses-Fenoll
M Trapero
F Molina-Jiménez
S Martín-Vilchez
P2860cites workEnhancement of lymphocyte proliferation, interleukin-2 production and NK activity by inmunoferon (AM-3), a fungal immunomodulator: variations in normal and immunosuppressed miceQ68811099
AM3, an adjuvant to hepatitis B revaccination in non-responder healthy personsQ72239984
Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cellsQ73035410
The immunosenescent phenotype in mice and humans can be defined by alterations in the natural immunity reversal by immunomodulation with oral AM3Q73108641
A new method for radioiodination of polysaccharides and its use in biodistribution studies of an immunomodulating glycoconjugate (Immunoferon)Q73633862
Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferón)Q74009212
The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cellsQ74055104
The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activationQ74195817
Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cellsQ74285101
Extracellular signal-regulated kinase, stress-activated protein kinase/c-Jun N-terminal kinase, and p38mapk are involved in IL-10-mediated selective repression of TNF-alpha-induced activation and maturation of human peripheral blood monocyte-derivedQ77320323
Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturationQ77353738
AM3 (Inmunoferón) as an adjuvant to hepatitis B vaccination in hemodialysis patientsQ77983681
Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cellsQ77999992
Solution structure of allergenic 2 S albuminsQ78541365
Identification and characterization of the peptidic component of the immunomodulatory glycoconjugate ImmunoferonQ78713179
AM3 inhibits LPS-induced iNOS expression in miceQ81781632
Interleukin-10 and the interleukin-10 receptorQ24290912
Solution structure of RicC3, a 2S albumin storage protein from Ricinus communisQ27642618
Toll-like receptorsQ27860671
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaQ28251443
Immunobiology of dendritic cellsQ29547465
AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN.Q30444275
A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizersQ32133166
The molecular pathogenesis of endotoxic shock and organ failureQ33594156
T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signalQ33774232
Differential expression of Rel/NF-kappaB and octamer factors is a hallmark of the generation and maturation of dendritic cellsQ33884442
Purification of KBF1, a common factor binding to both H-2 and beta 2-microglobulin enhancersQ33929799
Regulatory activity of autocrine IL-10 on dendritic cell functionsQ33938563
The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responsesQ34468846
Viral hepatitis C.Q35617324
Chemokines: multiple levels of leukocyte migration control.Q35753105
Uptake and presentation of orally administered antigensQ36055978
Hepatitis C virus and the immune system: a concise reviewQ36076877
Is hepatitis C virus infection of dendritic cells a mechanism facilitating viral persistence?Q36108089
AM3 inhibits HBV replication through activation of peripheral blood mononuclear cells.Q40548435
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Presence of functional dendritic cells in patients chronically infected with hepatitis C virusQ42980525
Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individualsQ42993342
Impaired allostimulatory function of dendritic cells in chronic hepatitis C infectionQ43001795
Immunoferon, a glycoconjugate of natural origin, inhibits LPS-induced TNF-alpha production and inflammatory responsesQ43769943
AM3 (a biological response modifier) in the treatment of recurrent aphthous stomatitis. Clinical evaluation and preliminary studies on NK (CD16) cells and their pathogenic role in the syndromeQ44214942
Immunoferon(R), an immunomodulator of natural origin, does not affect the rat liver cytochrome P-450 and phase II conjugation enzymesQ44438892
Therapeutic response of chronic active hepatitis B (CAHB) to a new immunomodulator: AM3. Immunohematological effectsQ44913659
Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infectionQ45737458
Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.Q51062725
Treatment with AM3 restores defective T-cell function in COPD patients.Q51984137
Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.Q52956682
Distinct patterns and kinetics of chemokine production regulate dendritic cell function.Q54093362
[Immunologic clinical evaluation of a biological response modifier, AM3, in the treatment of childhood infectious respiratory pathology]Q68025026
P4510describes a project that usesImageQuantQ112270642
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)698-708
P577publication date2008-04-14
P1433published inBritish Journal of PharmacologyQ919631
P1476titleAM3, a natural glycoconjugate, induces the functional maturation of human dendritic cells
P478volume154

Reverse relations

cites work (P2860)
Q39426735Corynebacterium pyruviciproducens promotes the production of ovalbumin specific antibody via stimulating dendritic cell differentiation and up-regulating Th2 biased immune response
Q35210594Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway
Q38166445Review article: management of chronic hepatitis C in patients with contraindications to anti-viral therapy
Q34321742Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis

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