scholarly article | Q13442814 |
P50 | author | Peter Schledermann Walmod | Q42691154 |
Kamil Gotfryd | Q47156173 | ||
P2093 | author name string | Elisabeth Bock | |
Vladimir Berezin | |||
Heinz Nau | |||
Maria Hansen | |||
Anna Kawa | |||
Ursula Ellerbeck | |||
P2860 | cites work | Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents | Q21198868 |
Glycogen synthase kinase 3: more than a namesake | Q24315635 | ||
Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats | Q27324438 | ||
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition | Q28301955 | ||
Valproic acid-induced spina bifida: a mouse model | Q28316245 | ||
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells | Q28366303 | ||
The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms | Q28568768 | ||
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen | Q29616224 | ||
HDAC6 modulates cell motility by altering the acetylation level of cortactin | Q30439626 | ||
Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis | Q30485641 | ||
Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation | Q30495932 | ||
Automated in vitro screening of teratogens | Q31062094 | ||
Discriminative power of an assay for automated in vitro screening of teratogens | Q33202681 | ||
MAP kinases and cell migration | Q35889220 | ||
GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder | Q36062876 | ||
Valproic acid as anti-cancer drug. | Q37018024 | ||
Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy | Q37156986 | ||
Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders. | Q37438513 | ||
What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam? | Q37639437 | ||
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth | Q38299684 | ||
Valproic acid enhances protein L-isoaspartyl methyltransferase expression by stimulating extracellular signal-regulated kinase signaling pathway | Q39860255 | ||
Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines | Q39867753 | ||
Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models | Q39924456 | ||
Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. | Q39940410 | ||
Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines. | Q40072387 | ||
Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells | Q40251579 | ||
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. | Q40483325 | ||
The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. | Q40970988 | ||
Anticonvulsant and neurotoxic activities of twelve analogues of valproic acid | Q42287628 | ||
Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect | Q42553750 | ||
The anticonvulsant sodium valproate specifically induces the expression of a rat glial heat shock protein which is identified as the collagen type IV receptor | Q42802803 | ||
Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells | Q43290186 | ||
Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons | Q44047015 | ||
Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid | Q44970276 | ||
Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds | Q45105674 | ||
Ras/MAP kinase pathways are involved in Ras specific apoptosis induced by sodium butyrate | Q46566506 | ||
Valproic acid induces extracellular signal-regulated kinase 1/2 activation and inhibits apoptosis in endothelial cells | Q46706734 | ||
Teratogenic potency of valproate analogues evaluated by quantitative estimation of cellular morphology in vitro | Q47792826 | ||
Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement | Q48374878 | ||
Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures. | Q52196687 | ||
[Structural bases of the teratogenic effects of the antiepileptic valproic acid. 2-n-propyl-4-pentenic acid, the first structural analogue with significantly higher teratogenic action than VPA]. | Q53037356 | ||
Studies on the teratogen pharmacophore of valproic acid analogues: evidence of interactions at a hydrophobic centre. | Q55477468 | ||
Correlation of in vitro anti-proliferative potential with in vivo teratogenicity in a series of valproate analogues. | Q55478740 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | teratogenicity | Q56246640 |
P304 | page(s) | 164-174 | |
P577 | publication date | 2011-04-18 | |
P1433 | published in | Basic and Clinical Pharmacology and Toxicology | Q15724438 |
P1476 | title | The teratogenic potencies of valproic acid derivatives and their effects on biological end-points are related to changes in histone deacetylase and Erk1/2 activities | |
P478 | volume | 109 |
Q55716842 | Antiepileptic drugs and pregnancy outcomes. |
Q34113695 | Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cells |
Q44152775 | Enantioselective apoptosis induction in histiocytic lymphoma cells and acute promyelocytic leukemia cells |
Q38040133 | Epigenetics of psychoactive drugs |
Q39031044 | Induction of neurotrophic and differentiation factors in neural stem cells by valproic acid |
Q34380256 | New perspectives of valproic acid in clinical practice. |
Q38077730 | Prenatal exposures associated with neurodevelopmental delay and disabilities |
Q40388690 | Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat. |
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