The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9.

scientific article published on 2 March 2011

The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00018-011-0639-0
P698PubMed publication ID21365281
P5875ResearchGate publication ID50251191

P50authorFrancisco Sánchez-MadridQ40058345
Peter N. MonkQ40648708
María Yáñez-MóQ41608595
Esther LafuenteQ58924364
Carlos CabanasQ58924489
P2093author name stringIsidoro González-Alvaro
Maria Dolores Gutiérrez-López
Carmen Domínguez
Susana Ovalle
Alvaro Gilsanz
P2860cites workEvidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein VQ24293698
Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusionQ24298326
Identification of SAP97 as an intracellular binding partner of TACEQ24298989
Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1Q24305944
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cellsQ24309589
Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor proteinQ24642700
Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysisQ24649625
Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin alpha6beta1: implications for murine fertilizationQ24675158
Tumor necrosis factor-alpha converting enzymeQ28208634
Complexes of tetraspanins with integrins: more than meets the eyeQ28210099
The ADAM metalloproteinasesQ28292696
Sequence-specific interaction between the disintegrin domain of mouse ADAM 3 and murine eggs: role of beta1 integrin-associated proteins CD9, CD81, and CD98.Q30307197
Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151Q33837431
Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzymeQ34559326
Lateral organization of membrane proteins: tetraspanins spin their web.Q34979935
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signalingQ35032897
Structure and functions of tumor necrosis factor-alpha converting enzymeQ35546050
Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane MicrodomainQ35564822
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.Q36074351
The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptorsQ36323845
The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferationQ36327499
Emerging roles for ectodomain shedding in the regulation of inflammatory responsesQ36432148
Membrane microdomains and proteomics: lessons from tetraspanin microdomains and comparison with lipid raftsQ36655075
Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatformsQ36955726
Regulation of the proteolytic disintegrin metalloproteinases, the 'Sheddases'.Q37289019
The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functionsQ37339450
Tetraspanin-enriched microdomains: a functional unit in cell plasma membranesQ37587580
Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1.Q39069264
Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factorQ39921892
The tetraspanin CD9 inhibits the proliferation and tumorigenicity of human colon carcinoma cells.Q40117083
FHL2 interacts with both ADAM-17 and the cytoskeleton and regulates ADAM-17 localization and activityQ40291367
Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1).Q40342802
Circulating adhesion molecules in diseaseQ40385135
Chronic ethanol enhances ectodomain shedding in T cells and monocytesQ40516032
Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linkingQ40626692
Application of peptides containing the cleavage sequence of pro-TNFalpha in assessing TACE activity of whole cells.Q40677184
A functionally relevant conformational epitope on the CD9 tetraspanin depends on the association with activated beta1 integrinQ40692932
Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.Q40740565
Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzymeQ40881816
Enhancement of the surface expression of tumor necrosis factor alpha (TNFalpha) but not the p55 TNFalpha receptor in the THP-1 monocytic cell line by matrix metalloprotease inhibitorsQ40980471
Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctionsQ41035046
Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophagesQ41067946
Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69.Q41579816
Regulation of the VLA integrin-ligand interactions through the beta 1 subunitQ41909450
Interleukin-15 and interferon-gamma participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor productionQ42058247
TACE/ADAM-17 enzymatic activity is increased in response to cellular stimulationQ42445689
ADAM17 but not ADAM10 mediates tumor necrosis factor-alpha and L-selectin shedding from leukocyte membranesQ43595800
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cellsQ45401643
Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasationQ57282535
Suppression of pulmonary metastasis using adenovirally motility related protein-1 (MRP-1/CD9) gene deliveryQ64380300
Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1Q67681256
Motility-related protein-1 (MRP-1/CD9) reduction as a factor of poor prognosis in breast cancerQ71102443
P433issue19
P304page(s)3275-3292
P577publication date2011-03-02
P1433published inCellular and Molecular Life SciencesQ5058352
P1476titleThe sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9
P478volume68

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cites work (P2860)
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Q59129990CD9 Controls Integrin α5β1-Mediated Cell Adhesion by Modulating Its Association With the Metalloproteinase ADAM17
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Q60045462Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

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