Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control

scientific article published on November 2000

Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/28.21.4340
P932PMC publication ID113140
P698PubMed publication ID11058134
P5875ResearchGate publication ID279399853

P2093author name stringH B Lieberman
K M Hopkins
H Hang
S J Rauth
P2860cites workHuman homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complexQ22008596
The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1Q22009947
DNA sequencing with chain-terminating inhibitorsQ22066207
Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonucleaseQ22253323
HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteinsQ22254258
The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9Q22254566
Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomesQ24309630
A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonucleaseQ24314103
Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint geneQ24314250
A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneQ24323298
Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosisQ24336800
Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damageQ24533206
HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control geneQ24548232
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombeQ24555694
Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.Q27933181
A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutantsQ27935496
cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogasterQ28116728
Checkpoints: controls that ensure the order of cell cycle eventsQ28131705
Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosisQ28141886
Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progressionQ28142735
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25Q28247761
Cell cycle control and cancerQ29617536
Fast and sensitive multiple sequence alignments on a microcomputerQ29618252
Molecular cloning and analysis of Schizosaccharomyces pombe rad9, a gene involved in DNA repair and mutagenesisQ33214952
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexesQ33617643
Checkpoint controls in Schizosaccharomyces pombe: rad1.Q33937604
Extragenic suppressors of Schizosaccharomyces pombe rad9 mutations uncouple radioresistance and hydroxyurea sensitivity from cell cycle checkpoint controlQ33965609
High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombeQ34236306
Separation of phenotypes in mutant alleles of the Schizosaccharomyces pombe cell-cycle checkpoint gene rad1+Q34454259
Cloning and characterisation of therad9DNA repair gene fromSchizosaccharomyces pombeQ35769782
Cell cycle analysisQ39351788
Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9Q39450987
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeastQ40365871
DNA structure checkpoints in fission yeastQ40406164
Schizosaccharomyces pombe Rad9 contains a BH3-like region and interacts with the anti-apoptotic protein Bcl-2.Q40853948
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.Q41164271
When checkpoints failQ41352428
DNA structure-dependent checkpoints in model systems.Q41679316
Checkpoint pathways come of age.Q41681106
Aberrations of the G1- and G1/S-regulating genes in human cancerQ41744192
Cell cycle checkpoints, chromosome stability and the progression of cancerQ41757943
Schizosaccharomyces malidevorans and Sz. octosporus homologues of Sz. pombe rad9, a gene that mediates radioresistance and cell-cycle progressionQ48077065
A general method for rapid site-directed mutagenesis using the polymerase chain reaction.Q48247178
Fission yeast genes involved in coupling mitosis to completion of DNA replicationQ63383735
Differential kinetics for induction of interleukin-6 mRNA expression in murine peritoneal macrophages: evidence for calcium-dependent and independent-signalling pathwaysQ77391458
P433issue21
P407language of work or nameEnglishQ1860
P921main subjecthydroxycarbamideQ212272
Schizosaccharomyces pombeQ2236682
P304page(s)4340-4349
P577publication date2000-11-01
P1433published inNucleic Acids ResearchQ135122
P1476titleMutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control
P478volume28

Reverse relations

cites work (P2860)
Q24313157Crystal structure of the human rad9-hus1-rad1 clamp
Q41283109Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

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