Shigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cells

scientific article published on 2 February 2011

Shigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1574-695X.2011.00778.X
P932PMC publication ID3055916
P698PubMed publication ID21219446

P50authorJames P NataroQ61771354
P2093author name stringEileen M Barry
Mauricio J Farfán
Cecilia S Toro
P2860cites workAggregative adherence fimbriae contribute to the inflammatory response of epithelial cells infected with enteroaggregative Escherichia coli.Q54638065
Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cellsQ73948765
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A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneriQ81785474
Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma proteinQ24315859
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
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Shigella flexneri 2a strain CVD 1207, with specific deletions in virG, sen, set, and guaBA, is highly attenuated in humansQ34003433
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
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MxiE regulates intracellular expression of factors secreted by the Shigella flexneri 2a type III secretion systemQ34316975
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OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulenceQ35073836
Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strainsQ35455031
Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccineQ35510455
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Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.Q36422508
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard roadQ36844719
Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporterQ37008377
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Pathogenesis of shigella diarrhea: evidence for an N-linked glycoprotein shigella toxin receptor and receptor modulation by beta-galactosidaseQ38351384
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
Prevalence of Shigella enterotoxins 1 and 2 among Shigella strains isolated from patients with traveler's diarrheaQ39453145
Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation.Q39831093
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesQ40198172
The secretion of the Shigella flexneri Ipa invasins is activated by epithelial cells and controlled by IpaB and IpaD.Q40793797
Contact of Shigella with host cells triggers release of Ipa invasins and is an essential function of invasivenessQ40806867
Developing live Shigella vaccines using lambda Red recombineeringQ41452880
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneriQ42638971
Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responsesQ44053369
IL-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of Shigella-induced colitis.Q51189374
Regulation of transcription by the activity of the Shigella flexneri type III secretion apparatus.Q54546861
P433issue3
P304page(s)332-339
P577publication date2011-02-02
P1433published inFEMS Immunology and Medical MicrobiologyQ15767550
P1476titleShigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cells
P478volume61