| scholarly article | Q13442814 |
| P2093 | author name string | Masakazu Hamada | |
| Yoshiaki Yura | |||
| Hidetaka Shimizu | |||
| Soichi Iwai | |||
| Tetsuei Miki | |||
| P2860 | cites work | The small GTPase RalA targets filamin to induce filopodia | Q22008839 |
| Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth | Q24294230 | ||
| The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
| RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival | Q24536042 | ||
| Coding sequences of human ralA and ralB cDNAs | Q24635845 | ||
| Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone | Q24681479 | ||
| Rho GTPases and the actin cytoskeleton | Q27860579 | ||
| Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility | Q28289336 | ||
| ras genes | Q29547799 | ||
| G1 phase progression: cycling on cue | Q29615162 | ||
| RHO-GTPases and cancer | Q29616099 | ||
| Protein prenylation: molecular mechanisms and functional consequences | Q29618038 | ||
| Ras superfamily monomeric G proteins in carcinoma cell motility | Q30310335 | ||
| RalA and RalB: antagonistic relatives in cancer cell migration | Q30437796 | ||
| Expression of ral GTPases, their effectors, and activators in human bladder cancer | Q30443973 | ||
| Ras mutations in United Kingdom examples of oral malignancies are infrequent | Q33560032 | ||
| Phase I adjuvant radiation with docetaxel in high-risk head and neck cancer | Q33717319 | ||
| p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA. | Q33781631 | ||
| Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. | Q34592093 | ||
| Distinct requirements for Ras oncogenesis in human versus mouse cells | Q34787097 | ||
| Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy. | Q34940620 | ||
| Ral-GTPases: approaching their 15 minutes of fame | Q35187818 | ||
| Oncogenic Ras and its role in tumor cell invasion and metastasis | Q35690261 | ||
| Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis? | Q35935797 | ||
| High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India | Q35984217 | ||
| Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation | Q36556010 | ||
| Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity | Q37108753 | ||
| Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation | Q37739922 | ||
| RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation | Q38309812 | ||
| RalA suppresses early stages of Ras-induced squamous cell carcinoma progression | Q39791607 | ||
| Induction of endonuclease G-mediated apopotosis in human oral squamous cell carcinoma cells by protein kinase C inhibitor safingol | Q40336740 | ||
| Activation of RalA is critical for Ras-induced tumorigenesis of human cells. | Q40410788 | ||
| RalGDS is required for tumor formation in a model of skin carcinogenesis. | Q40447001 | ||
| Phosphatidylinositol-3-OH kinase/AKT and survivin pathways as critical targets for geranylgeranyltransferase I inhibitor-induced apoptosis | Q40596813 | ||
| Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line | Q40937431 | ||
| The geranylgeranyltransferase I inhibitor GGTI-298 induces hypophosphorylation of retinoblastoma and partner switching of cyclin-dependent kinase inhibitors. A potential mechanism for GGTI-298 antitumor activity | Q40969125 | ||
| The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner | Q41085706 | ||
| RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription. | Q42799714 | ||
| Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor | Q44642906 | ||
| RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo. | Q46011136 | ||
| Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use. | Q47820459 | ||
| Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter. | Q48446950 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | oral squamous cell carcinoma | Q18553522 |
| cell migration | Q189092 | ||
| P304 | page(s) | 559-569 | |
| P577 | publication date | 2010-11-25 | |
| P1433 | published in | Cancer Chemotherapy and Pharmacology | Q326137 |
| P1476 | title | Involvement of RhoA and RalB in geranylgeranyltransferase I inhibitor-mediated inhibition of proliferation and migration of human oral squamous cell carcinoma cells | |
| P478 | volume | 68 |
| Q41959819 | Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts |
| Q89620715 | Cholesterol Serum Levels and Use of Statins in Graves' Orbitopathy: A New Starting Point for the Therapy |
| Q36746196 | Differential effect of zoledronic acid on human vascular smooth muscle cells |
| Q39257808 | Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation |
| Q38921817 | Involvement of RalB in the effect of geranylgeranyltransferase I on glioma cell migration and invasion |
| Q38933728 | Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression |
| Q47239374 | Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies |
| Q47340259 | RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer |
| Q38306683 | The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer |
| Q50789406 | [Effects of RhoA silencing on proliferation of tongue squamous cancer cells]. |
| Q98562940 | microRNA-495 alleviates endothelial cell inflammatory injury in coronary heart disease via blockade of the NF-κB pathway by targeting RALB |
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