Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA).

scientific article published on 30 June 2016

Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CEI.12834
P932PMC publication ID5011368
P698PubMed publication ID27357431

P2093author name stringR A Harris
Å Lernmark
C M Cilio
K Lynch
C-D Agardh
C Silver
M Radenkovic
J Arvastsson
P2860cites workFoxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Role of the B7-CD28/CTLA-4 pathway in autoimmune diseaseQ28217357
Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of diseaseQ28265611
Multiple immuno-regulatory defects in type-1 diabetesQ28344695
FOXP3+ regulatory T cells in the human immune systemQ29307487
Regulatory T cells and immune toleranceQ29616864
Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.Q34553677
Latent autoimmune diabetes in adults: A distinct but heterogeneous clinical entityQ34628948
CTLA-4: new insights into its biological function and use in tumor immunotherapyQ34711491
Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis studyQ36249785
LADA: time for a new definitionQ36560625
Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes SocietyQ37799656
Treg and CTLA-4: two intertwining pathways to immune toleranceQ38121260
Is CD69 an effective brake to control inflammatory diseases?Q38129638
Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cellsQ40425444
Hyperglycemia-induced activation of human T-lymphocytes with de novo emergence of insulin receptors and generation of reactive oxygen speciesQ46638473
Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies.Q51565693
Islet cell antibodies identify latent type I diabetes in patients aged 35-75 years at diagnosis.Q51634813
Cellular immune responses to human islet proteins in antibody-positive type 2 diabetic patients.Q54095939
Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults.Q54352401
Altered natural killer cells in type 1 diabetic patients.Q54565253
Role of the B7-CD28/CTLA-4 Pathway in Autoimmune DiseaseQ55879904
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
CD69: an unexpected regulator of TH17 cell-driven inflammatory responsesQ58063887
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cellsQ58234949
Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 DiabetesQ58328293
Pro- and anti-inflammatory cytokines in latent autoimmune diabetes in adults, type 1 and type 2 diabetes patients: Action LADA 4Q61478347
A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDMQ61861656
Latent autoimmune diabetes mellitus in adults (LADA): the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependencyQ72066129
The World Health Organization International Collaborative Study for islet cell antibodiesQ73193778
The CD4(+) regulatory T-cells is decreased in adults with latent autoimmune diabetesQ79148398
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetesQ79843142
CD4+CD25high regulatory T cells in human autoimmune diabetesQ81428869
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetesQ81690799
Abnormal T cell autoimmunity against GAD65 in LADA patientsQ82077060
Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiencyQ84086506
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectphenotypeQ104053
P304page(s)46-56
P577publication date2016-06-30
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleAltered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA).
P478volume186

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cites work (P2860)
Q92186396Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes
Q90324457Dipeptidyl peptidase-4(DPP-4) inhibitors: promising new agents for autoimmune diabetes
Q64983630Downregulation of T-Cell Transcription Factors in Adult Latent Autoimmune Diabetes with High-Titer Glutamic Acid Decaroxylase Antibody.
Q58065034First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
Q28555177Glibenclamide Prevents Diabetes in NOD Mice
Q91984134Past, present and future of latent autoimmune diabetes in adults
Q41787689Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C.
Q92431877Transcriptome profiling of microRNAs associated with latent autoimmune diabetes in adults (LADA)

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