scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1007/BF03189920 |
P698 | PubMed publication ID | 3294019 |
P2093 | author name string | F Jamali | |
P2860 | cites work | Inversion of optical configuration of alpha-methylfluorene-2-acetic acid (cicloprofen) in rats and monkeys | Q28316282 |
Isomeric inversion of ibuprofen (R)-enantiomer in humans | Q28342038 | ||
Stereospecific Inversion ofl-α-Methylfluorene-2-acetic Acid to itsd-Enantiomer in the Dog | Q28342527 | ||
Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology | Q34054672 | ||
Stereoselective disposition of indoprofen in surgical patients | Q34446729 | ||
Pharmacokinetics of ketoprofen in the elderly | Q34512945 | ||
Stereoselective disposition of ibuprofen enantiomers in man | Q34622724 | ||
Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer | Q39099127 | ||
The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequences | Q40092311 | ||
Interrelationships between xenobiotic metabolism and lipid biosynthesis | Q40153015 | ||
Antirheumatic drug concentrations in human synovial fluid and synovial tissue. Observations on extravascular pharmacokinetics | Q40165816 | ||
Stereoselective inversion of (R)-fenoprofen to (S)-fenoprofen in humans | Q42225734 | ||
Pharmacokinetics of the enantiomers of tiaprofenic acid in humans | Q43468221 | ||
Stereospecific assay and stereospecific disposition of racemic carprofen in rats | Q44251915 | ||
Inhibition of prostaglandin biosynthesis by clidanac and related compounds: structural and conformational requirements for PG synthetase inhibition | Q46165295 | ||
Optical isomerization of R(−)-clidanac to the biologically active S(+)-isomer in guinea-pigs | Q46226586 | ||
Pharmacokinetic analysis of the enantiomeric inversion of chiral nonsteroidal antiinflammatory drugs. | Q52573375 | ||
The stereoselective uptake of ibuprofen enantiomers into adipose tissue | Q57415361 | ||
The metabolism of ibuprofen | Q67267970 | ||
Stereospecific high-performance liquid chromatographic (HPLC) assay of fenoprofen enantiomers in plasma and urine | Q68064192 | ||
Pharmacokinetics of Ketoprofen Enantiomers in Young and Elderly Arthritic Patients following Single and Multiple Doses | Q68372040 | ||
Determination of the (+)- and (-)-enantiomers of pirprofen in human plasma by high-performance liquid chromatography | Q68819177 | ||
Enzymatic inversion at saturated carbon: nature and mechanism of the inversion of R(-) p-iso-butyl hydratropic acid | Q68877734 | ||
Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. III. Fenoprofen disposition | Q69728843 | ||
Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. IV. Ketoprofen disposition | Q69728847 | ||
Etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid): a potent antiinflammatory drug. Conformation and absolute configuration of its active enantiomer | Q69993234 | ||
Stereoselective gas chromatographic analysis of etodolac enantiomers in human plasma and urine | Q70017299 | ||
Ibuprofen stereoisomer hepatic clearance and distribution in normal and fatty in situ perfused rat liver | Q70062285 | ||
Pharmacokinetics of the enantiomers of indoprofen in man | Q70647051 | ||
Stereospecific inversion of (R)-(-)-benoxaprofen in rat and man | Q70680959 | ||
Pharmacokinetics of ketoprofen in patients with chronic renal failure | Q70957892 | ||
Optical inversion of (2R)- to (2S)-isomers of 2-[4-(2-Oxocyclopentylmethyl)-phenyl]propionic acid (loxoprofen), a new anti-inflammatory agent, and its monohydroxy metabolites in the rat | Q71350500 | ||
High-performance liquid chromatographic determination of stereoselective disposition of carprofen in humans | Q72097547 | ||
Biological activity of indoprofen and its optical isomers | Q72564486 | ||
Column liquid chromatography for the simultaneous determination of the enantiomers of loxoprofen sodium and its metabolites in human urine | Q93672885 | ||
P433 | issue | 1 | |
P921 | main subject | inflammation | Q101991 |
chirality | Q214514 | ||
pharmacokinetics | Q323936 | ||
enantiomer | Q494483 | ||
P304 | page(s) | 1-9 | |
P577 | publication date | 1988-01-01 | |
P1433 | published in | European Journal of Drug Metabolism and Pharmacokinetics | Q15757261 |
P1476 | title | Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs | |
P478 | volume | 13 |
Q74074491 | Bioinversion of ibuprofen enantiomers after administration in dogs: estimation of a novel index |
Q73472777 | Chiral bioequivalence: effect of absorption rate on racemic etodolac |
Q43892217 | Chiral inversion of (R)-ketoprofen: influence of age and differing physiological status in dairy cattle |
Q79846760 | Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol |
Q46238838 | Chiral kinetics and dynamics of ketorolac |
Q33937522 | Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach |
Q37905434 | Clinical pharmacokinetics 1990. |
Q34257894 | Clinical pharmacokinetics of dexketoprofen |
Q37290781 | Clinical pharmacokinetics of drugs used in juvenile arthritis |
Q37950598 | Clinical pharmacokinetics of ketoprofen and its enantiomers |
Q35572364 | Clinical pharmacokinetics of ketorolac tromethamine |
Q70490339 | Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations |
Q37550548 | Drug metabolism and pharmacokinetics |
Q37686952 | Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period. |
Q46152219 | Enantiomeric disposition of ketorolac in goats following administration of a single intravenous and oral dose |
Q40600044 | Enantiospecific analysis: applications in bioanalysis and metabolism |
Q44383561 | Enantiospecific disposition of pranoprofen in beagle dogs and rats |
Q34328918 | Etodolac clinical pharmacokinetics |
Q74603150 | HPLC determination of ketoprofen enantiomers in human serum using a nonporous octadecylsilane 1.5 microns column with hydroxypropyl beta-cyclodextrin as mobile phase additive |
Q38790686 | Implications of chirality and geometric isomerism in some psychoactive drugs and their metabolites |
Q73567796 | Involvement of the rat gut epithelial and muscular layer, and microflora in chiral inversion and acyl-glucuronidation of R-fenoprofen |
Q44345907 | Ketoprofen in the cat: pharmacodynamics and chiral pharmacokinetics. |
Q73082735 | Mechanistic studies on metabolic chiral inversion of 4-(4-methylphenyl)-2-methylthiomethyl-4-oxobutanoic acid (KE-748), an active metabolite of the new anti-rheumatic agent 2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid (KE-298), in rats |
Q69462559 | Mephenytoin stereoselective elimination in the rat: II. Comparison of mephenytoin stereoselective clearance during chronic intravenous and hepatic portal vein administration |
Q72766720 | Microbial metabolism of 2-arylpropionic acids: chiral inversion of ibuprofen and 2-phenylpropionic acid |
Q35536298 | Mirror images: the analysis of pharmaceutical enantiomers |
Q52304288 | Moment analysis of stereoselective enterohepatic circulation and unidirectional chiral inversion of ketoprofen enantiomers in rat. |
Q48106032 | Narrative review shows that the short-term use of ketorolac is safe and effective in the management of moderate-to-severe pain in children |
Q41113860 | New insights into the site and mode of antinociceptive action of flurbiprofen enantiomers |
Q54281565 | Optimized and Validated HPLC Methods for Compendial Quality Assessment. III. Testing of Optical Purity Applying α1-Acid-Glycoprotein Stationary Phase |
Q37944767 | Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs |
Q52290054 | Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse. |
Q64885687 | Pharmacokinetics of S(+)- and R(-)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis. |
Q39468679 | Preclinical and clinical development of dexketoprofen |
Q55067465 | Preclinical enantioselective pharmacology of (R)- and (S)- ketorolac. |
Q40861592 | Protein binding and stereoselectivity of nonsteroidal anti-inflammatory drugs |
Q73230433 | Quantification of ketoprofen enantiomers in human plasma based on solid-phase extraction and enantioselective column chromatography |
Q42011212 | Renal handling and effects of S(+)-ibuprofen and R(-)-ibuprofen in the rat isolated perfused kidney |
Q40950958 | Stereochemical aspects of pharmacotherapy |
Q70288917 | Stereoselective analysis of fenoprofen and its metabolites |
Q41240967 | Stereoselective arylpropionyl-CoA thioester formation in vitro |
Q73204572 | Stereoselective disposition and chiral inversion of KE-298, a new antirheumatic drug, in rats |
Q40515294 | Stereoselective glucuronidation and hydroxylation of etodolac by UGT1A9 and CYP2C9 in man. |
Q70261466 | Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral alpha 1-acid glycoprotein column |
Q67852136 | Stereoselective systemic disposition of ibuprofen enantiomers in the dog |
Q46382833 | Stereoselective taurine conjugation of (R)-benoxaprofen enantiomer in rats: in vivo and in vitro studies using rat hepatic mitochondria and microsomes |
Q37946823 | Stereoselectivity in clinical pharmacokinetics and drug development |
Q74609451 | Stereospecific pharmacokinetics and toxicodynamics of ketorolac after oral administration of the racemate and optically pure enantiomers to the rat |
Q54066798 | The in vitro metabolic inversion of R(-) to S(+) indoprofen |
Q44436022 | The stereoselective pharmacokinetics of etodolac in young and elderly subjects, and after cholecystectomy |
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