Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs

scientific article published on January 1988

Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1007/BF03189920
P698PubMed publication ID3294019

P2093author name stringF Jamali
P2860cites workInversion of optical configuration of alpha-methylfluorene-2-acetic acid (cicloprofen) in rats and monkeysQ28316282
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Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacologyQ34054672
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Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomerQ39099127
The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequencesQ40092311
Interrelationships between xenobiotic metabolism and lipid biosynthesisQ40153015
Antirheumatic drug concentrations in human synovial fluid and synovial tissue. Observations on extravascular pharmacokineticsQ40165816
Stereoselective inversion of (R)-fenoprofen to (S)-fenoprofen in humansQ42225734
Pharmacokinetics of the enantiomers of tiaprofenic acid in humansQ43468221
Stereospecific assay and stereospecific disposition of racemic carprofen in ratsQ44251915
Inhibition of prostaglandin biosynthesis by clidanac and related compounds: structural and conformational requirements for PG synthetase inhibitionQ46165295
Optical isomerization of R(−)-clidanac to the biologically active S(+)-isomer in guinea-pigsQ46226586
Pharmacokinetic analysis of the enantiomeric inversion of chiral nonsteroidal antiinflammatory drugs.Q52573375
The stereoselective uptake of ibuprofen enantiomers into adipose tissueQ57415361
The metabolism of ibuprofenQ67267970
Stereospecific high-performance liquid chromatographic (HPLC) assay of fenoprofen enantiomers in plasma and urineQ68064192
Pharmacokinetics of Ketoprofen Enantiomers in Young and Elderly Arthritic Patients following Single and Multiple DosesQ68372040
Determination of the (+)- and (-)-enantiomers of pirprofen in human plasma by high-performance liquid chromatographyQ68819177
Enzymatic inversion at saturated carbon: nature and mechanism of the inversion of R(-) p-iso-butyl hydratropic acidQ68877734
Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. III. Fenoprofen dispositionQ69728843
Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. IV. Ketoprofen dispositionQ69728847
Etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid): a potent antiinflammatory drug. Conformation and absolute configuration of its active enantiomerQ69993234
Stereoselective gas chromatographic analysis of etodolac enantiomers in human plasma and urineQ70017299
Ibuprofen stereoisomer hepatic clearance and distribution in normal and fatty in situ perfused rat liverQ70062285
Pharmacokinetics of the enantiomers of indoprofen in manQ70647051
Stereospecific inversion of (R)-(-)-benoxaprofen in rat and manQ70680959
Pharmacokinetics of ketoprofen in patients with chronic renal failureQ70957892
Optical inversion of (2R)- to (2S)-isomers of 2-[4-(2-Oxocyclopentylmethyl)-phenyl]propionic acid (loxoprofen), a new anti-inflammatory agent, and its monohydroxy metabolites in the ratQ71350500
High-performance liquid chromatographic determination of stereoselective disposition of carprofen in humansQ72097547
Biological activity of indoprofen and its optical isomersQ72564486
Column liquid chromatography for the simultaneous determination of the enantiomers of loxoprofen sodium and its metabolites in human urineQ93672885
P433issue1
P921main subjectinflammationQ101991
chiralityQ214514
pharmacokineticsQ323936
enantiomerQ494483
P304page(s)1-9
P577publication date1988-01-01
P1433published inEuropean Journal of Drug Metabolism and PharmacokineticsQ15757261
P1476titlePharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs
P478volume13

Reverse relations

cites work (P2860)
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