Pseudomonas aeruginosa ExoT acts in vivo as a GTPase-activating protein for RhoA, Rac1, and Cdc42.

scientific article published on April 2002

Pseudomonas aeruginosa ExoT acts in vivo as a GTPase-activating protein for RhoA, Rac1, and Cdc42. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.70.4.2198-2205.2002
P8608Fatcat IDrelease_5mzu5eocabajdoul5af4puu4im
P932PMC publication ID127837
P698PubMed publication ID11895987
P5875ResearchGate publication ID11467554

P2093author name stringJ N Engel
B I Kazmierczak
P2860cites workRho GTPases and the actin cytoskeletonQ27860579
The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesionsQ28239729
A novel regulator of p21-activated kinasesQ28281325
Rho GTPases control polarity, protrusion, and adhesion during cell movementQ29614244
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonQ29620156
S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.Q32060838
Yop effectors of Yersinia spp. and actin rearrangementsQ33900982
GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structureQ33904931
ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cellsQ34003121
The arginine finger domain of ExoT contributes to actin cytoskeleton disruption and inhibition of internalization of Pseudomonas aeruginosa by epithelial cells and macrophagesQ34005347
In vivo rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin ExoSQ34116489
Glucosylation of Rho proteins by Clostridium difficile toxin B.Q34312765
Enteropathogenic Escherichia coli inhibits phagocytosis.Q34489068
Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing.Q35404665
Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPasesQ36256190
Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells.Q39509496
Pseudomonas aeruginosa ExoT is a Rho GTPase-activating proteinQ39537017
Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells.Q39570589
Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneriQ40874006
Molecular genetic bases of Salmonella entry into host cellsQ41057366
YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cellsQ41476151
The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulenceQ41478657
Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosisQ41484833
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.Q42799773
Pseudomonas aeruginosa ExoT inhibits in vitro lung epithelial wound repairQ43572308
Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells.Q44095889
The Roles of Various Fractions of Pseudomonas aeruginosa in Its Pathogenesis: III. Identity of the Lethal Toxins Produced in Vitro and in VivoQ47714703
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.Q50124353
Rac1 and Cdc42 are required for phagocytosis, but not NF-kappaB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosaQ64449732
The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPasesQ73263462
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
P304page(s)2198-2205
P577publication date2002-04-01
P1433published inInfection and ImmunityQ6029193
P1476titlePseudomonas aeruginosa ExoT acts in vivo as a GTPase-activating protein for RhoA, Rac1, and Cdc42.
P478volume70

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cites work (P2860)
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