| P50 | author | Huib N. Caron | Q110632178 |
| | Lorenzo Rosasco | Q58376869 |
| P2093 | author name string | Rogier Versteeg | |
| | Alessandro Verri | |
| | Annalisa Barla | |
| | Luigi Varesio | |
| | Paolo Fardin | |
| | Sofia Mosci | |
| | Alessandra Eva | |
| | Jan J Molenaar | |
| | Ingrid Ora | |
| | Maura Puppo | |
| P2860 | cites work | Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 | Q24320257 |
| | Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway | Q24336803 |
| | Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis | Q24608039 |
| | Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers | Q25255387 |
| | Targeting HIF-1 for cancer therapy | Q27860504 |
| | Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains | Q28114920 |
| | The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages | Q28143066 |
| | Identification of genes differentially induced by hypoxia in pancreatic cancer cells | Q28203155 |
| | Exploiting tumour hypoxia in cancer treatment | Q28264146 |
| | Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression | Q60457335 |
| | High levels of HIF-2α highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche | Q60993213 |
| | Biologic factors determine prognosis in infants with stage IV neuroblastoma: A prospective Children's Cancer Group study | Q64225639 |
| | Exposure of cultured primary rat astrocytes to hypoxia results in intracellular glucose depletion and induction of glycolytic enzymes | Q73368028 |
| | Prognostic significance of MYCN oncogene expression in childhood neuroblastoma | Q77435844 |
| | Why do tumors become resistant to antiangiogenesis drugs? | Q84826712 |
| | HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascularization | Q84878606 |
| | Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas | Q93621132 |
| | Hypoxia inducible factor-2alpha in cancer. | Q36778663 |
| | Targeting hypoxia cell signaling for cancer therapy | Q36784388 |
| | Hypoxia, gene expression, and metastasis | Q36801457 |
| | High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma | Q36893712 |
| | An integrated cross-platform prognosis study on neuroblastoma patients | Q36925601 |
| | Enzyme substrate recognition in oxygen sensing: how the HIF trap snaps | Q36996499 |
| | The role of hypoxia-inducible factors in tumorigenesis. | Q37079708 |
| | In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model | Q37165842 |
| | International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee | Q37222603 |
| | An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. | Q37298556 |
| | Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration | Q37300245 |
| | HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells | Q37349993 |
| | Regulation of cancer cell metabolism by hypoxia-inducible factor 1. | Q37359659 |
| | Differential expression of neuronal genes defines subtypes of disseminated neuroblastoma with favorable and unfavorable outcome | Q38517752 |
| | Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions | Q39799433 |
| | Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha | Q39958635 |
| | Impact of supervised gene signatures of early hypoxia on patient survival | Q40127249 |
| | Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma | Q40168010 |
| | Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage | Q40192622 |
| | Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway | Q40266970 |
| | Mxi1 is induced by hypoxia in a HIF-1-dependent manner and protects cells from c-Myc-induced apoptosis. | Q40345618 |
| | Engineering of macrophages to produce IFN-gamma in response to hypoxia | Q40811274 |
| | Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene | Q42739835 |
| | Improved survival of children with neuroblastoma between 1979 and 2005: a report of the Italian Neuroblastoma Registry. | Q43567729 |
| | Plasma midkine level is a prognostic factor for human neuroblastoma | Q44412281 |
| | The recurrence patterns of stages I, II and III neuroblastoma: experience with 77 relapsing patients | Q44468456 |
| | Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation | Q45205131 |
| | Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification | Q46527475 |
| | Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells | Q47858902 |
| | Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome | Q48256079 |
| | Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas. | Q51593173 |
| | Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene. | Q51980889 |
| | Neuroblastoma | Q54265665 |
| | Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation. | Q54524140 |
| | Characterization of the expression of the hypoxia-induced genes neuritin, TXNIP and IGFBP3 in cancer. | Q55042012 |
| | Plasma levels of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in patients with neuroblastoma | Q56997850 |
| | Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification | Q57270614 |
| | Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype | Q57517773 |
| | Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers | Q58211840 |
| | Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis | Q28279053 |
| | Hypoxia upregulates the histone demethylase JMJD1A via HIF-1 | Q28571015 |
| | Oxygen tension regulates the expression of a group of procollagen hydroxylases | Q28583010 |
| | Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha | Q28586044 |
| | Hypoxia--a key regulatory factor in tumour growth | Q29547318 |
| | Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis | Q29614537 |
| | N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis | Q30983520 |
| | Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes | Q33258311 |
| | HIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma | Q33291872 |
| | Subclassification and individual survival time prediction from gene expression data of neuroblastoma patients by using CASPAR. | Q33377405 |
| | Identification and characterization of hypoxia-induced genes in Carassius auratus blastulae embryonic cells using suppression subtractive hybridization | Q33391611 |
| | A compact VEGF signature associated with distant metastases and poor outcomes | Q33418745 |
| | Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction | Q33427301 |
| | A regularized method for selecting nested groups of relevant genes from microarray data | Q33443272 |
| | Modulation of angiogenic and inflammatory response in glioblastoma by hypoxia | Q33470265 |
| | The l1-l2 regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines | Q33510814 |
| | Regulation of glucose transport by hypoxia | Q33684400 |
| | Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group | Q33876841 |
| | Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma | Q34038480 |
| | Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype | Q34068218 |
| | Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma | Q34162893 |
| | Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology | Q34343405 |
| | Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation | Q34357440 |
| | Advances in the diagnosis and treatment of neuroblastoma | Q34534073 |
| | Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study | Q34606771 |
| | Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma | Q34733110 |
| | Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'. | Q35617266 |
| | The HIF pathway as a therapeutic target | Q35876589 |
| | The role of hypoxia-induced factors in tumor progression | Q35980392 |
| | Integration of oxygen signaling at the consensus HRE. | Q36290265 |
| | A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter | Q36365615 |
| | Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation | Q36530574 |
| | Role of hypoxia-inducible factor-1alpha as a cancer therapy target | Q36720704 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neuroblastoma | Q938205 |
| | patient | Q181600 |
| | hypoxia | Q105688 |
| P304 | page(s) | 185 | |
| P577 | publication date | 2010-07-12 | |
| P1433 | published in | Molecular Cancer | Q15724585 |
| P1476 | title | A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients | |
| P478 | volume | 9 | |