Proteasomal degradation unleashes the pro-death activity of androgen receptor

scientific article

Proteasomal degradation unleashes the pro-death activity of androgen receptor is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CR.2010.65
P932PMC publication ID5702544
P698PubMed publication ID20479785
P5875ResearchGate publication ID44608753

P2093author name stringJialing Xiang
Yuting Lin
Bradley Godfrey
Bonnie Haferkamp
Jeffery Larson
P2860cites workStructure and function of steroid receptor AF1 transactivation domains: induction of active conformationsQ24537137
Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cellsQ24675586
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sitesQ30309352
Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancerQ33180363
Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptorsQ33651363
Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.Q33961079
Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivityQ34433798
Androgen and its receptor promote Bax-mediated apoptosisQ34519663
The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancerQ35584838
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).Q35836715
Androgen receptor is a tumor suppressor and proliferator in prostate cancerQ36858442
Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptorQ36864165
The role of the polyglutamine tract in androgen receptor.Q36975170
Androgen receptor-mediated apoptosis is regulated by photoactivatable androgen receptor ligandsQ37073935
Diverse roles of androgen receptor (AR) domains in AR-mediated signalingQ37210875
Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/HrkQ37352951
Molecular cloning and structural analysis of complementary DNA of human and rat androgen receptorsQ38342620
Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cellsQ39947179
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independenceQ40073673
GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanismsQ40179207
Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cellsQ40218951
Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregatesQ40781435
Inhibiting proteasomes in human HepG2 and LNCaP cells increases endogenous androgen receptor levelsQ40852524
Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domainQ41157407
Activation of the human androgen receptor through a protein kinase A signaling pathwayQ41174500
Androgen receptors: structures, mutations, antibodies and cellular dynamicsQ43555554
The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence proteinQ43615480
Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicityQ46593765
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptorQ60594517
Identification of three proline-directed phosphorylation sites in the human androgen receptorQ71758582
Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tractQ73561135
Apoptosis: translating theory to therapy for prostate cancerQ74270601
Expression of extended polyglutamine sequentially activates initiator and effector caspasesQ77341954
Androgen Receptors in Prostate CancerQ79075118
P433issue10
P304page(s)1138-1147
P577publication date2010-05-18
P1433published inCell ResearchQ1524018
P1476titleProteasomal degradation unleashes the pro-death activity of androgen receptor
P478volume20

Reverse relations

cites work (P2860)
Q38951017AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy.
Q37322621Androgen receptor (AR) positive vs negative roles in prostate cancer cell deaths including apoptosis, anoikis, entosis, necrosis and autophagic cell death
Q39243442Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression
Q37357034Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters
Q36024044Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells
Q35100137Modulation of the tumor cell death pathway by androgen receptor in response to cytotoxic stimuli
Q36439635Nuclear export signal of androgen receptor (NESAR) regulation of androgen receptor level in human prostate cell lines via ubiquitination and proteasome-dependent degradation