Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern

scientific article published on 26 April 2010

Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1742-4658.2010.07658.X
P932PMC publication ID2901513
P698PubMed publication ID20456499
P5875ResearchGate publication ID44586402

P50authorJens WaschkeQ1687388
René P. ZahediQ42329557
P2093author name stringAlbert Sickmann
Michaela Kuhn
Michael Hartmann
Birgit Gassner
Juliane Schröter
Alexandra Gazinski
P2860cites workGlobal analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stabilityQ27937057
Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalizeQ28285604
A membrane form of guanylate cyclase is an atrial natriuretic peptide receptorQ28566956
Genome-wide association study identifies eight loci associated with blood pressureQ29614414
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometryQ29619562
Alternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signalingQ30371510
Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulationQ31816687
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.Q33784330
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptorQ33995684
Phosphoproteome of resting human plateletsQ34726895
Guanylyl cyclase-linked receptorsQ35254194
Structure, Regulation, and Function of Mammalian Membrane Guanylyl Cyclase Receptors, With a Focus on Guanylyl Cyclase-AQ35561813
Domain analysis of human transmembrane guanylyl cyclase receptors: implications for regulationQ36071657
Selected reaction monitoring for quantitative proteomics: a tutorialQ36973024
Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A.Q39750341
Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7.Q39828839
Role of extracellular domain dimerization in agonist-induced activation of natriuretic peptide receptor A.Q40061214
Homologous and lysophosphatidic acid-induced desensitization of the atrial natriuretic peptide receptor, guanylyl cyclase-A, in MA-10 leydig cells.Q40306783
The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatasesQ40753432
Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transductionQ41166663
Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptideQ41273237
Dephosphorylation of the guanylyl cyclase-A receptor causes desensitizationQ41613147
Expression, purification, and characterization of the intra-cellular domain of the ANP receptorQ42102703
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertensionQ42280521
Ligand binding-dependent limited proteolysis of the atrial natriuretic peptide receptor: juxtamembrane hinge structure essential for transmembrane signal transductionQ42615921
Metabolic radiolabeling: experimental tool or Trojan horse? (35)S-Methionine induces DNA fragmentation and p53-dependent ROS production.Q43654441
Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopyQ46136567
Enhanced activity of the myocardial Na+/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice.Q46745879
Physiological hydrostatic pressure protects endothelial monolayer integrityQ46918414
The protein kinase domain of the ANP receptor is required for signalingQ69374143
p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblastsQ77954392
Role of cyclic GMP and calcineurin in homologous and heterologous desensitization of natriuretic peptide receptor-AQ80094351
Fluorescent sensors for rapid monitoring of intracellular cGMPQ82043755
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
desensitizationQ2700499
atrial natriuretic peptideQ78185357
P304page(s)2440-2453
P577publication date2010-04-26
P1433published inFEBS JournalQ1388041
P1476titleHomologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern
P478volume277

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cites work (P2860)
Q51053075A Glutamate-Substituted Mutant Mimics the Phosphorylated and Active Form of Guanylyl Cyclase-A.
Q35546884A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide
Q34270975A functional screen provides evidence for a conserved, regulatory, juxtamembrane phosphorylation site in guanylyl cyclase a and B.
Q35622455ANP-induced signaling cascade and its implications in renal pathophysiology
Q64065395Active propagation of dendritic electrical signals in C. elegans
Q34626812Allosteric modification, the primary ATP activation mechanism of atrial natriuretic factor receptor guanylate cyclase
Q37827835Catch me if you can: mass spectrometry-based phosphoproteomics and quantification strategies.
Q38987185Chronic heart failure as a state of reduced effectiveness of the natriuretic peptide system: implications for therapy
Q36159149Endothelial actions of atrial and B-type natriuretic peptides
Q38620496Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice
Q41223771Mass Spectrometric Identification of Phosphorylation Sites in Guanylyl Cyclase A and B
Q38794203Molecular Physiology of Membrane Guanylyl Cyclase Receptors
Q53871284Mutation of a conserved lysine in the kinase homology domain reduces the natriuretic peptide-dependent activity and phosphorylation of guanylyl cyclase-A.
Q37917873Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling
Q34906523Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor
Q39103593Receptor Guanylyl Cyclases in Sensory Processing.
Q36867743Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases
Q91686461Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition
Q34990290Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase
Q45299510The good, the bad, the ugly: validating the mass spectrometric analysis of modified peptides