Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5).

scientific article published on 26 April 2010

Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/MOL.110.064055
P8608Fatcat IDrelease_hikipnyrmrg3jp7ph6mc2dcxwe
P932PMC publication ID2912054
P698PubMed publication ID20421347
P5875ResearchGate publication ID43345555

P50authorFarzin FarzanehQ40658885
Gwyn T WilliamsQ61054638
P2093author name stringMirna Mourtada-Maarabouni
Anwar M Hasan
P2860cites workmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4EQ24301780
Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genesQ24522827
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptorQ24650793
TOR signaling in growth and metabolismQ27860757
The Ki-67 protein: from the known and the unknownQ28143714
A mammalian gene with introns instead of exons generating stable RNA productsQ28273163
Upstream and downstream of mTORQ28277365
Immunopharmacology of rapamycinQ28285198
Genes specifically expressed at growth arrest of mammalian cellsQ28297811
Participation of p53 protein in the cellular response to DNA damageQ29618319
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycinQ29620399
Improved method for computing potential doubling time from flow cytometric dataQ30578502
Forward genetics in mammalian cells: functional approaches to gene discoveryQ30763509
The use of gene function to identify the rate-limiting steps controlling cell fateQ31035770
TemsirolimusQ33377310
The host gene for intronic U17 small nucleolar RNAs in mammals has no protein-coding potential and is a member of the 5'-terminal oligopyrimidine gene familyQ33775140
The coordinate regulation of the p53 and mTOR pathways in cellsQ33840457
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterizationQ33920766
The gas 5 gene shows four alternative splicing patterns without coding for a proteinQ33923333
Glucocorticoids in T cell development and function*.Q33932702
Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasisQ33992131
Synthesis of the translational apparatus is regulated at the translational levelQ34058830
Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA functionQ34658630
Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5).Q34763432
mTOR, translational control and human disease.Q36013966
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4EQ36827075
Role of mTOR in anticancer drug resistance: perspectives for improved drug treatmentQ36844334
Targeting the mTOR signaling network in cancer.Q36955694
Sarcophine-diol, a Chemopreventive Agent of Skin Cancer, Inhibits Cell Growth and Induces Apoptosis through Extrinsic Pathway in Human Epidermoid Carcinoma A431 CellsQ37109455
Mammalian target of rapamycin as a target in hematological malignanciesQ37227074
mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylationQ39969679
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.Q40054340
Effects of silymarin on the spontaneous proliferation and cell cycle of human peripheral blood leukemia T cellsQ40145522
Characterization of a glucocorticoid-sensitive human lymphoid cell lineQ40500344
Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting dosesQ40643579
Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and developmentQ40655817
Molecular failure of apoptosis: inappropriate cell survival and mutagenesis?Q40972997
Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycinQ41412030
Isolation of genes controlling apoptosis through their effects on cell survival.Q42225487
Effects of nutrient deprivation and differentiation on the expression of growth-arrest genes (gas and gadd) in F9 embryonal carcinoma cellsQ42989552
Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivinQ44189760
The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.Q45110090
The gas5 gene is disrupted by a frameshift mutation within its longest open reading frame in several inbred mouse strains and maps to murine chromosome 1.Q52531629
Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytesQ52833019
Activation of T and B lymphocytes by insoluble phytomitogensQ68991405
Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulationQ74595877
SnapShot: mTOR signalingQ80193487
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.Q105219584
P433issue1
P921main subjectsirolimusQ32089
P304page(s)19-28
P577publication date2010-04-26
P1433published inMolecular PharmacologyQ1943386
P1476titleInhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5).
P478volume78

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