review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/9780470122914.CH7 |
P953 | full work available at URL | https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F9780470122914.ch7 |
https://onlinelibrary.wiley.com/doi/full/10.1002/9780470122914.ch7 | ||
P698 | PubMed publication ID | 345770 |
P2093 | author name string | J. P. Klinman | |
P2860 | cites work | Journal of the American Chemical Society | Q898902 |
Journal of the Chemical Society | Q903605 | ||
Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect | Q24617542 | ||
Free-energy profile of the reaction catalyzed by triosephosphate isomerase | Q28297525 | ||
Mechanistic studies on the rat kidney flavoenzyme L-α-hydroxy acid oxidase | Q28338857 | ||
Dihydroxyacetone phosphate. Its structure and reactivity with -glycerophosphate dehydrogenase, aldolase and triose phosphate isomerase and some possible metabolic implications | Q28363056 | ||
A Correlation of Reaction Rates | Q30051437 | ||
Nuclear magnetic resonance studies of substrate interaction with cobalt substituted alcohol dehydrogenase from liver | Q33234368 | ||
Application of secondary alpha-deuterium kinetic isotope effects to studies of enzyme catalysis. Glycoside hydrolysis by lysozyme and beta-glucosidase | Q34232772 | ||
The catalytic mechanism of carbonic anhydrase | Q34732308 | ||
Radical mechanisms for 1,5-dihydroflavin reduction of carbonyl compounds | Q35078410 | ||
Carbon dioxide hydration activity of carbonic anhydrase: paradoxical consequences of the unusually rapid catalysis | Q35107661 | ||
The Catalytic Mechanism of Carbonic Anhydrase. Hydrogen-Isotope Effects on the Kinetic Parameters of the Human C Isoenzyme | Q39067712 | ||
A new reaction of glutamate dehydrogenase: the enzyme-catalyzed formation of trinitrobenzene from TNBS in the presence of reduced coenzyme | Q68744774 | ||
The rate-determining step in the oxidative decarboxylation of isocitric acid | Q68754571 | ||
Deuterium isotope effects and chemically modified coenzymes as mechanism probes of yeast glyoxalase-I | Q69351930 | ||
One-proton catalysis in the deacetylation of acetyl-a-chymotrypsin | Q69483724 | ||
The effects of 2H2O on mammary glucose-6-phosphate dehydrogenase | Q70050302 | ||
Kinetic isotope effects in the NAD- and NADP-specific isocitrate dehydrogenases of pig heart | Q70055544 | ||
Nitrogen isotope effects on the chymotrypsin-catalyzed hydrolysis of N-acetyl-L-tryptophanamide | Q70391222 | ||
Mechanism of action of aspartase. A kinetic study and isotope rate effects with 2 H | Q70410787 | ||
Acetoacetate decarboxylase. Identification of the rate-determining step in the primary amine catalyzed reaction and in the enzymic reaction | Q70452630 | ||
Rate-determining step in the acylation of papain by N-benzoly-L-argininamide | Q70452632 | ||
Stereochemistry of the interconversions of citrate and acetate catalyzed by citrate synthase, adenosine triphosphate citrate lyase, and citrate lyase | Q70727251 | ||
Secondary isotope effects in reactions catalyzed by yeast and muscle aldolase | Q71221674 | ||
Carbon isotope effects on the enzymatic decarboxylation of glutamic acid | Q71459492 | ||
Fate of chiral acetates in the citric acid cycle | Q71500092 | ||
Substrate concentration dependence of deuterium isotope effects on beef heart lactate dehydrogenase | Q71725481 | ||
l-amino acid oxidase. II. Deuterium isotope effects and the action mechanism for the reduction of l-amino acid oxidase by l-leucine | Q71757513 | ||
Participation of an Acidic Group in the Chymotrypsin Catalysis*** | Q72458017 | ||
Secondary isotope effects in the dehydration of malic acid by fumarate hydratase | Q72489673 | ||
KINETICS OF PAPAIN-CATALYZED HYDROLYSIS OF ALPHA-N-BENZOYL-L-ARGININE ETHYL ESTER AND ALPHA-N-BENZOYL-L-ARGININAMIDE | Q78358485 | ||
Fumarase activity in deuterium oxide | Q79081549 | ||
The formation of a stable aldolase-dihydroxyacetone phosphate complex | Q79400315 | ||
Divalent cation and pH-dependent primary isotope effects in the enolase reaction | Q93745730 | ||
Solvent isotope effect in inorganic pyrophosphatase-catalyzed hydrolysis of inorganic pyrophosphate | Q39084085 | ||
Participation of buffer in the catalytic mechanism of carbonic anhydrase | Q39097435 | ||
Dual divalent cation requirement for activation of pyruvate kinase: essential roles of both enzyme- and nucleotide-bound metal ions | Q39102308 | ||
Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies | Q39135502 | ||
Isotope effect studies of the role of the metal ions in isocitrate dehydrogenase | Q39139376 | ||
Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution | Q39990970 | ||
The effect of methanol and dioxan on the rates of the β-galactosidase-catalysed hydrolyses of some β-d-galactopyranosides: rate-limiting degalactosylation. The pH-dependence of galactosylation and degalactosylation | Q41825362 | ||
The beta-galactosidase-catalysed hydrolyses of beta-d-galactopyranosyl pyridium salts. Rate-limiting generation of an enzyme-bound galactopyranosyl cation in a process dependent only on aglycone acidity | Q42148666 | ||
Kinetics of the diamine oxidase reaction | Q42923293 | ||
The mechanism of action of beta-galactosidase. Effect of aglycone nature and -deuterium substitution on the hydrolysis of aryl galactosides | Q42923605 | ||
Mercaptide-imidazolium ion-pair: the reactive nucleophile in papain catalysis | Q43480902 | ||
Isotope effects and structure-reactivity correlations in the yeast alcohol dehydrogenase reaction. A study of the enzyme-catalyzed oxidation of aromatic alcohols | Q43542432 | ||
Energetics of triosephosphate isomerase: deuterium isotope effects in the enzyme-catalyzed reaction | Q43864102 | ||
Energetics of triosephosphate isomerase: the fate of the 1(R)-3H label of tritiated dihydroxyacetone phsophate in the isomerase reaction | Q44377698 | ||
Studies on the intramolecular and intermolecular kinetic isotope effects in pyruvate carboxylase catalysis | Q46947873 | ||
Mechanism for lysozyme-catalyzed hydrolysis. | Q52470610 | ||
Monovalent cation-induced association of formyltetrahydrofolate synthetase subunits. Solvent isotope effect | Q52864211 | ||
Equilibrium perturbation by isotope substitution | Q52864223 | ||
Partition analysis and concept of net rate constants as tools in enzyme kinetics | Q52872618 | ||
Steady-state analysis of kinetic isotope effects in enzymic reactions | Q52874671 | ||
Characterization and chemical modifications of toxins isolated from the venoms of the sea snake, Laticauda semifasciata, from Philippines | Q53809013 | ||
Model dehydrogenase reactions. Reduction of N-methylacridinium ion by reduced nicotinamide adenine dinucleotide and its derivatives. | Q53849794 | ||
The mechanism of the aminolysis of acetate esters. | Q54149332 | ||
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. | Q54642095 | ||
Use of Hydrogen Isotope Effects to Identify the Attacking Nucleophile in the Enolization of Ketones Catalyzed by Acetic Acid1-3 | Q56456392 | ||
Asymmetric Methyl Groups: Asymmetric Methyl Groups, and the Mechanism of Malate Synthase | Q58975577 | ||
Asymmetric Methyl Groups: Preparation and Detection of Chiral Methyl Groups | Q58975581 | ||
Kinetic Isotope Effects in the Acetolyses of Deuterated Cyclopentyl Tosylates1,2 | Q59663177 | ||
The Magnitude of the Primary Kinetic Isotope Effect for Compounds of Hydrogen and Deuterium | Q60059594 | ||
Model dehydrogenase reaction. Charge distribution in the transition state | Q66935044 | ||
Kinetic isotope effects for the chymotrypsin catalyzed hydrolysis of ethoxyl-18O labeled specific ester substrates | Q66935126 | ||
Secondary isotope effect in the phosphorylase reaction | Q67289646 | ||
Uncatalyzed rates of enolization of dihydroxyacetone phosphate and of glyceraldehyde 3-phosphate in neutral aqueous solution. Quantitative assessment of the effectiveness of an enzyme catalyst | Q67322504 | ||
SN2-like transition for methyl transfer catalyzed by catechol-O-methyltransferase | Q67444807 | ||
Carbon isotope effect of the enzymatic decarboxylation of pyruvic acid | Q67499466 | ||
A comparison of the glutamate dehydrogenase catalyzed oxidation of NADPH by trinitrobenzenesulfonate with the uncatalyzed reaction | Q67790473 | ||
Mechanism of action of serine proteases: tetrahedral intermediate and concerted proton transfer | Q67877036 | ||
Energetics of triosephosphate isomerase: the appearance of solvent tritium in substrate dihydroxyacetone phosphate and in product | Q67877040 | ||
Energetics of triosephosphate isomerase: the appearance of solvent tritium in substrate glyceraldehyde 3-phosphate and in product | Q67877042 | ||
Reactions of dihydronicotinamides. I. Evidence for an intermediate in the reduction of trifluoroacetophenone by 1-substituted dihydronicotinamides | Q68482730 | ||
[Kinetic studies of some mechanisms of lactate dehydrogenase with the tritium isotope effect] | Q68581126 | ||
Transients in the reactions of liver alcohol dehydrogenase | Q68616852 | ||
Mechanism of enzyme action | Q68667366 | ||
Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase reaction | Q68676340 | ||
Substituent effects on the pre-steady-state kinetics of oxidation of benzyl alcohols by liver alcohol dehydrogenase | Q68708102 | ||
Deuterium solvent isotope effects in reactions catalyzed | Q68733757 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | deuterium | Q102296 |
isotope of carbon | Q471790 | ||
P304 | page(s) | 415-494 | |
P577 | publication date | 1978-01-01 | |
P1433 | published in | Advances in Enzymology and Related Areas of Molecular Biology | Q15759701 |
P1476 | title | Kinetic isotope effects in enzymology | |
Kinetic Isotope Effects in Enzymology | |||
P478 | volume | 46 |