Fibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells

scientific article published on 29 March 2010

Fibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/LABINVEST.2010.71
P698PubMed publication ID20351696

P50authorYoshikazu KinoshitaQ108291777
P2093author name stringShunji Ishihara
Hiroshi Imaoka
Yuji Amano
Hiroyuki Fukuhara
Kenji Furuta
Hiroshi Tobita
Yasunori Kadowaki
Md Monowar Aziz
Farzana B Rahman
P2860cites workInflammation and cancerQ24649640
Putting tumours in contextQ28207789
The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cellsQ28262541
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent mannerQ28275516
Stromal fibroblasts in cancer initiation and progressionQ29618873
Cdx2 as a Marker of Epithelial Intestinal Differentiation in the EsophagusQ30311906
Know thy neighbor: stromal cells can contribute oncogenic signalsQ34132830
Cellular transformation by SV40 large T antigen: interaction with host proteinsQ34177960
Correlation between manometric and pH tests for gastro-oesophageal refluxQ34473232
Reflux, Barrett's oesophagus and adenocarcinoma: burning questionsQ35210012
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiationQ36098246
Fibroblast-mediated acceleration of human epithelial tumor growth in vivoQ37657276
Presence of simian virus 40 DNA sequences in diffuse large B-cell lymphomas in Tunisia correlates with aberrant promoter hypermethylation of multiple tumor suppressor genes.Q38872031
Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation modelQ39773312
Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagusQ40752328
Cdx1 and cdx2 expression during intestinal developmentQ40847809
Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junctionQ40871662
DNA tumor virus transforming proteins and the cell cycleQ40886495
Fibroblasts can modulate the phenotype of malignant epithelial cells in vitroQ41092884
Expression of cyclooxygenase 2, microsomal prostaglandin E synthase 1, and EP receptors is increased in rat oesophageal squamous cell dysplasia and Barrett's metaplasia induced by duodenal contents refluxQ42008475
Enhanced expression of interleukin-8 and activation of nuclear factor kappa-B in endoscopy-negative gastroesophageal reflux diseaseQ42460374
Mutual induction of growth factor gene expression by epidermal-dermal cell interactionQ42769779
Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epitheliumQ42844302
Concentration of refluxed acid and esophageal mucosal injuryQ46158663
Multifocal heterogeneity in villin and Ep-CAM expression in Barrett's esophagus.Q53455769
HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation.Q54650079
Barrett's metaplasiaQ58105006
Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal AdenocarcinomaQ58204833
Cytokeratin and CDX-2 expression in Barrett's esophagusQ61814039
Differential activation of cytokine secretion in primary human colonic fibroblast/myofibroblast culturesQ73834082
Cytokeratin subsets can reliably distinguish Barrett's esophagus from intestinal metaplasia of the stomachQ74628028
Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosaQ78865239
Roles of caudal-related homeobox gene Cdx1 in oesophageal epithelial cells in Barrett's epithelium developmentQ83172283
P433issue7
P304page(s)1033-1048
P577publication date2010-03-29
P1433published inLaboratory InvestigationQ6467260
P1476titleFibroblast-derived HB-EGF promotes Cdx2 expression in esophageal squamous cells
P478volume90

Reverse relations

cites work (P2860)
Q53169856Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins.
Q37809363Cdx genes, inflammation, and the pathogenesis of intestinal metaplasia
Q53067339Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.
Q35638683Genomic signatures reveal new evidences for selection of important traits in domestic cattle.
Q26766641Role of nitric oxide in the pathogenesis of Barrett's-associated carcinogenesis
Q28073714The role of cancer-associated fibroblasts in esophageal cancer
Q39307834The role of nitric oxide in the induction of caudal-type homeobox 2 through epidermal growth factor receptor in the development of Barrett's esophagus.
Q42119412Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.

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