Database of mutations within the adenovirus 5 E1A oncogene

scientific article published on January 1, 1998

Database of mutations within the adenovirus 5 E1A oncogene is …
instance of (P31):
scholarly articleQ13442814

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P8978DBLP publication IDjournals/nar/Mymryk98
P356DOI10.1093/NAR/26.1.292
P953full work available at URLhttp://academic.oup.com/nar/article-pdf/26/1/292/7048218/26-1-292.pdf
https://academic.oup.com/nar/article-pdf/26/1/292/7048218/26-1-292.pdf
https://europepmc.org/articles/PMC147177
https://europepmc.org/articles/PMC147177?pdf=render
P932PMC publication ID147177
P698PubMed publication ID9399857
P5875ResearchGate publication ID13830034

P2093author name stringJ. S. Mymryk
P2860cites workRegulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma proteinQ38319003
Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cellsQ40788858
Identification and analysis of a retinoblastoma binding motif in the replication protein of a plant DNA virus: requirement for efficient viral DNA replicationQ40789160
Adenovirus-E1A proteins transform cells by sequestering regulatory proteinsQ40823566
Tumour suppressive properties of the adenovirus 5 E1A oncogeneQ41191473
Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein.Q41576846
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.Q42648852
Definition of adenovirus type 5 functions involved in the induction of chromosomal aberrations in human cellsQ43693588
An adenovirus E1a protein region required for transformation and transcriptional repressionQ44198736
Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activationQ44516091
Structure of two spliced mRNAs from the transforming region of human subgroup C adenovirusesQ53580928
A region of SV40 large T antigen can substitute for a transforming domain of the adenovirus E1A productsQ59044880
Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanismQ64377862
Isolation and characterization of insertion mutants in E1A of adenovirus type 5Q64378407
Comparison of nucleotide sequences of the early E1a regions for subgroups A, B and C of human adenovirusesQ64381687
Inhibition of IFN-stimulated gene expression and IFN induction of cytolytic resistance to natural killer cell lysis correlate with E1A-p300 bindingQ64382957
Adenovirus 5 E1A induced differentiation of P19 embryonal carcinoma cells requires binding to p300Q64383279
HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma familyQ24319768
A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasisQ24321630
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shockQ24648784
Physical interaction of the retinoblastoma protein with human D cyclinsQ28269103
Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene productQ28284880
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptorQ28286827
Interaction of rat Cdc37-related protein with retinoblastoma gene productQ28564915
Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformationQ30311302
Cyclic AMP signaling is required for function of the N-terminal and CR1 domains of adenovirus E1A in Saccharomyces cerevisiae.Q30463702
Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteinsQ33929346
A novel adenovirus-2 E1A mRNA encoding a protein with transcription activation propertiesQ33929351
Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cellsQ34436312
Cellular targets for transformation by the adenovirus E1A proteinsQ34438094
Adenovirus E1A targets key regulators of cell proliferationQ35260997
Adenovirus E1a as a tumor-suppressor geneQ35882444
Mapping of the mAb73 epitope on Ad2 E1A proteins with random peptide libraries and deletion mutantsQ36673708
The amino-terminal portion of CD1 of the adenovirus E1A proteins is required to induce susceptibility to tumor necrosis factor cytolysis in adenovirus-infected mouse cellsQ36681830
E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteinsQ36694428
E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma productsQ36729356
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activityQ36783092
Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle productsQ36835368
Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.Q36845795
E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely relatedQ36897529
Transcriptional and Transforming Activities of the Adenovirus E1A ProteinsQ37113939
Ability of adenovirus 5 E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300 kDa cellular proteinQ37374420
Repression of the interferon signal transduction pathway by the adenovirus E1A oncogeneQ37590901
Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.Q37686223
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
fact databaseQ1393704
databaseQ8513
P304page(s)292-294
P577publication date1998-01-01
P1433published inNucleic Acids ResearchQ135122
P1476titleDatabase of mutations within the adenovirus 5 E1A oncogene
P478volume26

Reverse relations

cites work (P2860)
Q40392107Accumulation of p53 in response to adenovirus early region 1A sensitizes human cells to tumor necrosis factor alpha-induced apoptosis
Q28566098Interaction between the HPV E7 oncoprotein and the transcriptional coactivator p300
Q28213526NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction
Q40571413The targeting of the proteasomal regulatory subunit S2 by adenovirus E1A causes inhibition of proteasomal activity and increased p53 expression
Q41488880p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing

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