Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding Mode.

scientific article

Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding Mode. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/ML200249H
P932PMC publication ID4025668
P698PubMed publication ID24900442

P50authorThierry FischmannQ67982013
P2093author name stringXiaohua Huang
Xianshu Yang
José S Duca
Matthew Richards
Cliff C Cheng
Gerald W Shipps
P2860cites workGlobal cancer statisticsQ22241238
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Targeting the replication checkpoint using SCH 900776, a potent and functionally selective CHK1 inhibitor identified via high content screeningQ39592286
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P433issue2
P407language of work or nameEnglishQ1860
P304page(s)123-128
P577publication date2012-01-20
P1433published inACS Medicinal Chemistry LettersQ2819061
P1476titleDiscovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding Mode
P478volume3

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cites work (P2860)
Q388416532-(3'-Indolyl)-N-arylthiazole-4-carboxamides: Synthesis and evaluation of antibacterial and anticancer activities
Q51251348Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: Amide⋅⋅⋅Heteroarene π-Stacking Interactions and Chalcogen Bonding in the S3 Pocket.
Q51545880Noticing the unnoticed: bridging structural data and drug design.
Q26864870Structure-based design, discovery and development of checkpoint kinase inhibitors as potential anticancer therapies

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