| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P50 | author | Richard Flavell | Q2149481 |
| P2093 | author name string | Chen Dong | |
| Roza I Nurieva | |||
| Piper Treuting | |||
| Julie Duong | |||
| P2860 | cites work | ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 | Q22001503 |
| Human IL-17: a novel cytokine derived from T cells | Q24304404 | ||
| IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis | Q24563235 | ||
| T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines | Q24678115 | ||
| T-cell co-stimulation through B7RP-1 and ICOS | Q28141589 | ||
| ICOS co-stimulatory receptor is essential for T-cell activation and function | Q28187985 | ||
| ICOS is critical for CD40-mediated antibody class switching | Q28589705 | ||
| Differential T cell costimulatory requirements in CD28-deficient mice | Q28590647 | ||
| ICOS is essential for effective T-helper-cell responses | Q28594859 | ||
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| The T cell activation molecule H4 and the CD28-like molecule ICOS are identical | Q40840282 | ||
| Collagen-induced arthritis, an animal model of autoimmunity | Q41639546 | ||
| Interleukin-17: A new bone acting cytokine in vitro | Q42476956 | ||
| Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction | Q43945860 | ||
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| CD28-deficient mice are highly resistant to collagen-induced arthritis. | Q54109027 | ||
| Cutting edge: critical role of inducible costimulator in germinal center reactions | Q56905311 | ||
| IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis | Q64379692 | ||
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| Rheumatoid arthritis | Q71046923 | ||
| Characterization of H4: a mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor | Q71785417 | ||
| Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells | Q73112924 | ||
| Interleukin-17 up-regulation of nitric oxide production in human osteoarthritis cartilage | Q73414178 | ||
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| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 701-706 | |
| P577 | publication date | 2003-03-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Inducible costimulator is essential for collagen-induced arthritis. | |
| P478 | volume | 111 |
| Q40726014 | A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis |
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| Q37243055 | An overview of IL-17 function and signaling |
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| Q35607509 | B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses |
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| Q81245701 | CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response |
| Q33809102 | Candida-elicited murine Th17 cells express high Ctla-4 compared with Th1 cells and are resistant to costimulation blockade |
| Q35644278 | Control of autoimmune diseases by the B7-CD28 family molecules. |
| Q28252911 | Costimulation blockade in the treatment of rheumatic diseases |
| Q56900516 | Critical role of activation-inducible lymphocyte immunomediatory molecule/inducible costimulator in the effector function of human T cells: a comparative in vitro study of effects of its blockade and CD28 blockade in human beings and monkeys |
| Q38333262 | Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cells |
| Q46085284 | Defining dose-response relationships in the therapeutic blockade of B7RP-1-dependent immune responses |
| Q42235704 | Development of kidney glomerular endothelial cells and their role in basement membrane assembly |
| Q24674584 | Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression |
| Q38357683 | Down-regulation of inducible co-stimulator (ICOS) by intravitreal injection of small interfering RNA (siRNA) plasmid suppresses ongoing experimental autoimmune uveoretinitis in rats |
| Q37360656 | Emergence of the Th17 pathway and its role in host defense. |
| Q34279731 | Evidence for ligand-independent multimerization of the IL-17 receptor |
| Q36449975 | Expanding the effector CD4 T-cell repertoire: the Th17 lineage. |
| Q34897236 | Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-gamma and anti-double-stranded DNA antibody production |
| Q43885391 | Expression of inducible co-stimulator on peripheral blood T lymphocytes in patients with lupus nephritis |
| Q79769520 | Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression |
| Q36302329 | Follicular B helper T cells in antibody responses and autoimmunity. |
| Q38812644 | Follicular helper T cell in immunity and autoimmunity |
| Q37992393 | Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: implication to clinical therapeutics |
| Q39101574 | Harnessing the immunotherapeutic potential of T-lymphocyte co-signaling molecules in transplantation |
| Q51985886 | Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency. |
| Q62734291 | ICOS and B7 costimulatory molecule expression identifies activated cellular subsets in rheumatoid arthritis |
| Q51765773 | ICOS deficiency results in exacerbated IL-17 mediated experimental autoimmune encephalomyelitis. |
| Q44987186 | ICOS is essential for the development of experimental autoimmune myasthenia gravis |
| Q80752705 | ICOS mediates the development of insulin-dependent diabetes mellitus in nonobese diabetic mice |
| Q33615233 | ICOS promotes IL-17 synthesis in colonic intraepithelial lymphocytes in IL-10-/- mice |
| Q81434987 | ICOS-B7 homologous protein interactions are necessary for mercury-induced autoimmunity |
| Q46023260 | ICOS-induced B7h shedding on B cells is inhibited by TLR7/8 and TLR9. |
| Q35907840 | IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis |
| Q35951805 | IL-12 and IL-23: master regulators of innate and adaptive immunity. |
| Q29547525 | IL-23 drives a pathogenic T cell population that induces autoimmune inflammation |
| Q39488557 | Immunoreactivity of two novel monoclonal antibodies against human inducible co-stimulator ligand |
| Q36699777 | In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells |
| Q54609816 | Inducible co-stimulator (ICOS) is upregulated in experimental autoimmune uveoretinitis. |
| Q92190807 | Interleukin (IL)-21 in Inflammation and Immunity During Parasitic Diseases |
| Q79461211 | Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4 |
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| Q56900336 | JTA-009, a fully human antibody against human AILIM/ICOS, ameliorates graft-vs-host reaction in SCID mice grafted with human PBMCs |
| Q35911103 | Molecular targets in immune-mediated diseases: focus on rheumatoid arthritis |
| Q80022540 | Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice |
| Q36059553 | Novel treatments for systemic lupus erythematosus |
| Q53619773 | Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. |
| Q37781913 | Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets |
| Q54444518 | Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity. |
| Q36228311 | Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis |
| Q28247470 | Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? |
| Q53912899 | Regulation of immune and autoimmune responses by ICOS. |
| Q47725412 | Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway |
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| Q91407378 | Role of Co-stimulatory Molecules in T Helper Cell Differentiation |
| Q35720250 | Role of FAS in HIV infection |
| Q46624594 | Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis |
| Q51983263 | Role of inducible costimulator in the development of lupus in MRL/lpr mice. |
| Q34229305 | Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon |
| Q51043312 | Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis. |
| Q38856510 | Synovial fluid proteome in rheumatoid arthritis |
| Q36972497 | T-cell co-stimulatory pathways in autoimmunity |
| Q40218688 | T-cell costimulation blockade in immunologic diseases: role of CD28 family members |
| Q35753672 | T-cell regulation in rheumatoid arthritis |
| Q44417403 | TLR2 and TLR4 differentially regulate B7-1 resulting in distinct cytokine responses to the mycoplasma superantigen MAM as well as to disease induced by Mycoplasma arthritidis |
| Q42427813 | TLR9-dependent IL-23/IL-17 is required for the generation of Stachybotrys chartarum-induced hypersensitivity pneumonitis |
| Q38150101 | Targeting co-stimulatory pathways: transplantation and autoimmunity |
| Q37739486 | Targeting lymphocyte co-stimulation: from bench to bedside |
| Q33854453 | Targeting the Human T-Cell Inducible COStimulator Molecule with a Monoclonal Antibody Prevents Graft-vs-Host Disease and Preserves Graft vs Leukemia in a Xenograft Murine Model |
| Q34973340 | Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice |
| Q28240070 | The B7 family revisited |
| Q35998858 | The balance of immune responses: costimulation verse coinhibition |
| Q35581696 | The immunological synapse for B-cell memory: the role of the ICOS and its ligand for the longevity of humoral immunity |
| Q36317934 | The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target |
| Q36664672 | The role of B cells in animal models of rheumatoid arthritis |
| Q37474910 | The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency. |
| Q39785791 | The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. |
| Q79236386 | The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis |
| Q36638912 | The therapeutic potential of positive and negative immune cell co-stimulation during inflammation |
| Q30991375 | Therapeutic opportunities in the B7/CD28 family of ligands and receptors |
| Q87274147 | Thymic TFH cells involved in the pathogenesis of myasthenia gravis with thymoma |
| Q35603065 | Transgenic animals in inflammatory disease models |
| Q37974990 | Treatment of systemic lupus erythematosus: new advances in targeted therapy |
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