Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience.

scientific article published on 26 March 2016

Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IJROBP.2016.03.011
P932PMC publication ID5199017
P698PubMed publication ID27212198

P50authorDavid I. RosenthalQ57015055
Voichita Bar-AdQ89259195
Adam S GardenQ90650674
P2093author name stringQuynh-Thu Le
Andy Trotti
Paul M Harari
Christopher U Jones
George Shenouda
Jonathan Harris
David Raben
Sharon A Spencer
Robert L Foote
Guobin Song
Rita Axelrod
Qiang Ed Zhang
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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancerQ28240089
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials GroupQ29619344
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.Q33178143
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survivalQ33515519
Clinical predictors of severe cetuximab-induced rash: observations from 933 patients enrolled in north central cancer treatment group study N0147.Q33722621
First-cycle rash and survival in patients with advanced non-small-cell lung cancer receiving cetuximab in combination with first-line chemotherapy: a subgroup analysis of data from the FLEX phase 3 study.Q33775197
Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.Q34171999
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Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidinesQ36628049
High-grade acute organ toxicity as positive prognostic factor in adjuvant radiation and chemotherapy for locally advanced head and neck cancerQ37845600
The effect of cytotoxic chemotherapy on the risk of high-grade acneiform rash to cetuximab in cancer patients: a meta-analysis.Q37852910
A proposed EGFR inhibitor dermatologic adverse event-specific grading scale from the MASCC skin toxicity study group.Q39901967
Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancerQ40493345
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Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.Q44260431
Radiotherapy with concomitant weekly docetaxel for Stages III/IV oropharynx carcinoma. Results of the 98-02 GORTEC Phase II trialQ44707465
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Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinomaQ46816802
Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer.Q46942430
How well does the MESTT correlate with CTCAE scale for the grading of dermatological toxicities associated with oral tyrosine kinase inhibitors?Q51752873
Correlation between efficacy and skin rash occurrence following treatment with the epidermal growth factor receptor inhibitor cetuximab: a single institution retrospective analysis.Q51768055
High-grade acute organ toxicity as a positive prognostic factor in primary radiochemotherapy for anal carcinoma.Q51812300
Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer.Q54668284
Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-BaseQ57949385
Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancersQ73145497
First-line single-agent cetuximab in patients with advanced colorectal cancerQ80180429
Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CQ84243064
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcetuximabQ420296
head and neck cancerQ1783924
head and neck carcinomaQ18554836
neck cancerQ18966654
P304page(s)1346-1354
P577publication date2016-03-26
P1433published inInternational Journal of Radiation Oncology Biology PhysicsQ2296252
P1476titleCorrelation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience
P478volume95