Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.

scientific article

Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2017/3270725
P932PMC publication ID5385220
P698PubMed publication ID28458925

P50authorFlavio RizzolioQ57544256
Carol F LippaQ87962401
Yuesong GongQ87962404
P2093author name stringTongzheng Liu
Shaohui Huang
Richard Tsai
Yungen Xu
Lingyan Xu
Silvia Boffo
Frances E Chow
Zhiyun Ren
P2860cites workMemory and mental status correlates of modified Braak staging.Q52170951
PIN1, the cell cycle and cancer.Q53561253
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau proteinQ22010198
A  Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's DiseaseQ22241518
Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyondQ22251042
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta productionQ24309767
Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteinsQ24329069
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disordersQ24337114
Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonismQ24530210
Shank3 mutant mice display autistic-like behaviours and striatal dysfunctionQ24597501
Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapsesQ24619395
Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autismQ24620573
Rapamycin fed late in life extends lifespan in genetically heterogeneous miceQ24647805
Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylationQ27934506
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptideQ28131750
The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor proteinQ28198177
Phosphorylation-specific prolyl isomerization: is there an underlying theme?Q28248256
Identification of novel phosphorylation sites on postsynaptic density proteinsQ28281343
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expressionQ28566984
Prolyl isomerase Pin1 regulates neuronal differentiation via β-cateninQ28586339
Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantineQ29465775
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesisQ29547501
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxinsQ29547593
Alzheimer's disease is a synaptic failureQ29547670
Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome systemQ29617400
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaquesQ30486499
PIN1 gene variants in Alzheimer's diseaseQ30883650
Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferationQ30885629
Comprehensive identification of phosphorylation sites in postsynaptic density preparationsQ33232861
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1Q34068097
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disordersQ34138025
Pin1 and PKMzeta sequentially control dendritic protein synthesisQ34274733
Alzheimer disease therapy: can the amyloid cascade be halted?Q34828328
Association of membrane rafts and postsynaptic density: proteomics, biochemical, and ultrastructural analysesQ35249037
Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory lossQ35918370
Extracellular level of GABA and Glu: in vivo microdialysis-HPLC measurementsQ36512995
The postsynaptic densityQ36545830
Pin1 in Alzheimer's diseaseQ36582738
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and diseaseQ36945537
Extracellular glutamate concentration in hippocampal sliceQ37163189
Review: disruption of the postsynaptic density in Alzheimer's disease and other neurodegenerative dementiasQ37790804
Preventing Alzheimer's diseaseQ39549596
Amyloid peptide attenuates the proteasome activity in neuronal cellsQ40375322
Neurotransmitters drive combinatorial multistate postsynaptic density networks.Q41184685
Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitabilityQ41892623
Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's diseaseQ42558615
Characterization of the proteome, diseases and evolution of the human postsynaptic density.Q42610204
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.Q44532915
Postsynaptic density assembly is fundamentally different from presynaptic active zone assembly.Q44762697
Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.Q46425942
Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cellsQ46466667
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.Q47763676
Continual remodeling of postsynaptic density and its regulation by synaptic activityQ48128407
Diagnostic criteria for neuropathologic assessment of Alzheimer's diseaseQ48662480
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysisQ48858833
A rapid method for preparing synaptosomes: comparison, with alternative proceduresQ49135145
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
synaptic plasticityQ1551556
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1Q21116190
P304page(s)3270725
P577publication date2017-03-26
P1433published inNeural PlasticityQ15716605
P1476titlePathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease
P478volume2017

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cites work (P2860)
Q89972068Downregulation of miR-33 Has Protective Effect Against Aβ₂₅₋₃₅-Induced Injury in SH-SH-SY5Y Cells
Q90722392Liraglutide Treatment Ameliorates Neurotoxicity Induced by Stable Silencing of Pin1
Q97521007Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?
Q96155773Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer's Disease
Q58795095Pin1 Modulation in Physiological Status and Neurodegeneration. Any Contribution to the Pathogenesis of Type 3 Diabetes?
Q59812522Prolyl Isomerase Pin1 Directly Regulates Calcium/Calmodulin-Dependent Protein Kinase II Activity in Mouse Brains

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